Research & Teaching Faculty

  1. Research & Teaching Faculty
  2. Department Publications

Department Publications

Submitted

Yang, C. ; Xiaozhu, W. ; Xiaolei, S. ; M., C. Susanne; L., M. G. Patrick; O., W. Michael; Chris, O. Biological Imaging With Medium-Sensitive Bichromatic Flexible Fluorescent Dyes. Angewandte Chemie International Edition Submitted, 56, 15603-15606.
Saadati, F. ; Griffin, S. E. ; Schafer, L. L. Guanidinate Early-Transition-Metal Complexes: Efficient And Selective Hydroaminoalkylation Of Alkenes. Organometallics Submitted, null.
Submitted.

2026

Javeria, H. ; Yahaya, N. ; Mohamed, A. Husaini; Kamaruzaman, S. ; Zain, N. Nadhirah M. ; Herzog, G. ; Chen, D. ; Hong, L. Sheh Stimuli-Responsive (Switchable) Deep Eutectic Solvents In Microextraction: Status, Challenges And Prospects In Food Safety And Environmental Analysis. Talanta 2026, 130863.
Geng, X. ; Qiu, Z. ; Zhang, C. ; Li, H. ; Chen, D. D. Y. Survey Of Volatile Organic Compounds Released At Different Temperatures From Tea By Direct Analysis In Real Time Mass Spectrometry. Food Chemistry 2026, 148128.
Yang, C. ; Shannon, C. P. ; Assadian, S. ; Hui, A. ; Checkervarty, A. ; Zheng, A. ; Kim, E. ; Espín, E. ; Rajasekaran, A. ; Toma, M. ; Huan, T. ; Tebbutt, S. J. Metabolomic Biomarkers Predict Early Cardiac Allograft Vasculopathy: A Pilot Study. The Journal of Heart and Lung Transplantation 2026, 45, 73.
Xu, L. ; Zhang, C. ; Li, H. ; Chen, D. Da Yong Direct Characterization Of Polysaccharides With In-Source Derivatization And Tandem Mass Spectrometry. Analytical Chemistry 2026.
Wang, H. ; Zhang, Y. ; Bi, W. ; Chen, D. D. Y. Sustainable And High Efficiency Natural Hydrophobic Deep Eutectic Solvents In Analytical Chemistry. TrAC Trends in Analytical Chemistry 2026, 198, 118736.
Kuhlmann, A. - S. ; Hamlin, D. K. ; Li, Y. ; Wang, X. ; Li, L. ; Orvig, C. ; Kiem, H. - P. ; Sandmaier, B. M. ; D. Wilbur, S. ; Pincus, S. ; Harrington, R. D. In Vitro Evaluation Of Anti-Hiv Radioimmunoconjugates Labeled With Astatine-211, Thorium-227 And Actinium-225. Nucl. Med. Biol. 2026, 154-155, 109602.
Fernández-Pavón, D. ; de Blas, A. ; Martínez-Cabanas, M. ; Barriada, J. L. ; Patrick, B. O. ; Orvig, C. ; Bénard, F. ; Yang, H. ; Wharton, L. ; Jaraquemada-Pelaez, Mde Guadalu; Rodríguez-Blas, T. Challenging The Macrocycle Paradigm: Four-Arm, High-Denticity Acyclic Chelators For Radiopharmaceuticals Incorporating Actinium And Lanthanides. Inorg. Chem. 2026, 65, 6836-6860.
Qiu, Z. ; Xu, L. ; Geng, X. ; Li, H. ; Chen, D. D. Y. Online Monitoring Of Maillard Reaction Dynamics Using A Custom Reaction-Transfer Device And Direct Analysis In Real Time Mass Spectrometry. Food Chemistry 2026, 525, 150511.
Martinez-Blanco, G. ; Baker, D. V. ; Py, B. ; Rassachack, E. ; Ciucci, F. ; Bizzotto, D. Redox Active Dna Sams Investigated Using A Probabilistic Approach For Estimating Distribution Of Differential Capacity. Electrochimica Acta 2026, 575, 149451.
Voskoboinyk, D. ; Tanner, M. E. Murnac-Based Electrophilic Inhibitors Of O-Acetylpeptidoglycan Esterase (Ape): Design, Synthesis, And Kinetic Evaluation. Chem. Eur. J. 2026, in press.
Teindl, K. ; Jacobs, D. ; Panetier, J. A. ; Nichols, E. M. Highly Acidic Second Coordination Spheres Promote In Situ Formation Of Iron Phlorins Exhibiting Fast And Selective Co2 Reduction. Journal of the American Chemical Society 2026.
Chandra, S. Deo; Gunasekera, S. ; n, T́n Trung; Froelich, J. ; Miao, S. ; Morin, G. B. ; Chen, D. D. Y. ; Patrick, B. O. ; Perrin, D. M. Unlocking Potent Amatoxin Antibody−Drug Conjugates Using Structure−Activity Studies On Δ-Substituted-Γ-Hydroxy Isoleucine. Journal of Medicinal Chemistry 2026, 69, in press.
Wang, Y. ; Xu, L. ; Gu, T. ; Li, H. ; Chen, D. D. Y. Direct Identification And Quantification Of Flavonoids And Their Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry. Rapid Communications in Mass Spectrometry 2026, 40, e10169.
Yu, H. ; Biswas, P. ; Rideout, E. ; Cao, Y. ; Fiehn, O. ; Huan, T. Bago: A Self-Optimizing Tool For Lc-Ms Gradient Design In Metabolomics. Analytical Chemistry 2026, 98, 18660–18672.
Xu, L. ; Gao, S. ; Wang, Y. ; Zhang, L. ; Li, H. ; Wang, Y. ; Chen, D. D. Y. Characterization Of Gas-Phase Charge-Site Isomerism In Flavonoids And Flavonoid Glycosides By Cyclic Ion Mobility-Mass Spectrometry With Computational Validation. Analytical Chemistry 2026, 98, 3871 - 3879.
Low, B. ; Nguyen, C. ; Huan, T. The Multifaceted Challenge Of Normalizing Mass Spectrometry-Based Metabolomics Data. Analytical Chemistry 2026, 98, 13967–13974.
Huan, T. ; Li, X. Disinfection Byproducts In The Long-Tail Exposome: Unmet Challenges For Water Quality And Human Health. Environmental Science & Technology 2026, 60, 13255–13258.
Xu, L. ; Sha, D. ; Ren, R. ; Li, H. ; Chen, D. D. Y. Methylation In Ambient Ion Source Enables Direct Isomer Differentiation Of Oligosaccharides By Tandem Mass Spectrometry. Carbohydrate Polymers 2026, 373, 124493.
Espín, E. ; Yang, C. ; Shannon, C. P. ; Checkervarty, A. K. ; Kim, S. ; Lapp, L. ; Assadian, S. ; Grunau, B. ; Goldfarb, D. M. ; Hutton, J. ; Huan, T. ; Tebbutt, S. J. Pilot Longitudinal Integrated Transcriptomic–Metabolomic Study Reveals Immune And Metabolic Signatures In Non-Hospitalized Healthcare Workers With Long Covid. Frontiers in Cellular and Infection Microbiology 2026, 16, 1808564.

2025

Xu, L. ; Bai, Z. ; Li, H. ; Chen, D. D. Y. Instrumental Analysis Experiment: Direct Surface Analysis Of Personal Protective Equipment. Journal of Chemical Education 2025.
Miyamoto, Y. ; Tsubouchi, M. ; Momose, T. Exploring Nuclear Spin Conservation In The Ch2 + H2 Reaction. The Journal of Physical Chemistry Letters 2025, 16, 1739–1745.
Hedges, J. B. ; Marchand, J. A. ; Calvó-Tusell, C. ; Wei, Z. - W. ; Millar, D. C. ; Garcia-Borràs, M. ; C Y Chang, M. ; Ryan, K. S. Terminal Alkyne Formation By A Pyridoxal Phosphate-Dependent Enzyme. Nat. Chem. Biol. 2025.
Tan, J. ; Negri, G. L. ; Morin, G. B. ; Chen, D. D. Y. Attribute-Weighted Aggregation Of Tandem Mass Reporter Ion Intensity For Protein Quantification Using Isobaric Labeling. Journal of Proteome Research 2025, 24, 4875-4887.
Kim, E. ; Huan, T. Disentangling Method-Induced Differences In Metabolomics: Single- Versus Dual-Phase Extraction. Analyst 2025, 151, 2842–2851.
Akbari, R. ; Alves, B. X. R. ; Baker, C. J. ; Baquero-Ruiz, M. ; Bertsche, W. ; Butler, E. ; Burrows, C. ; Capra, A. ; Cesar, C. L. ; Charlton, M. ; Collister, R. ; Cridland, A. ; Eriksson, S. ; Evans, A. ; Evans, L. T. ; Evetts, N. ; Fajans, J. ; Friesen, T. ; Fujiwara, M. C. ; Gill, D. R. ; Grandemange, P. ; Granum, P. ; Gutierrez, A. ; Hangst, J. S. ; Hayden, M. E. ; Hodgkinson, D. ; Isaac, C. A. ; Ishida, A. ; Johnson, M. A. ; Jones, J. M. ; Jones, S. A. ; Jonsell, S. ; Khramov, A. ; Kurchaninov, L. ; Little, A. ; Madsen, N. ; Maxwell, D. ; McKenna, J. T. K. ; Menary, S. ; Michan, J. M. ; Momose, T. ; Mullan, P. S. ; Olchanski, K. ; Olin, A. ; Peszka, J. ; Povilus, A. ; Powell, A. ; Pusa, P. ; Rasmussen, C. Ø. ; Sacramento, R. L. ; Sameed, M. ; Sarid, E. ; Silveira, D. M. ; So, C. ; Stracka, S. ; Stutter, G. ; Tharp, T. D. ; Thompson, R. I. ; Torkzaban, C. ; van der Werf, D. P. ; Wurtele, J. S. The Alpha-2 Apparatus - Facilitating Experimentation With Trapped Antihydrogen. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 2025, 1072, 170194.
Rothchild, K. W. ; Berry, D. ; Hagar, M. ; Mirotadze, N. ; Ryan, K. S. Fungal Sulfotransferase From Metarhizium Majus Catalyzes The Formation Of Ppz Pathway Intermediate Peramine-8-O-Sulfate. Org. Lett. 2025, 27, 7261–7265.
Wei, Z. - W. ; Daniel-Ivad, P. ; Zhang, L. ; Ryan, K. S. Structure And Mechanism Of The Azomycin Biosynthetic Enzyme Rohq That Catalyzes A Spontaneous Cyclodehydration. J. Am. Chem. Soc. 2025, 147, 25117–25122.
Zhao, C. ; Zhao, T. ; Shen, Q. ; Tang, Z. ; Li, X. ; Huan, T. Practical Guidance For Training Machine Learning Models In Metabolomics And Mass Spectrometry Research. Analytical Chemistry 2025, 97, 23005–23013.
Baker, C. J. ; Bertsche, W. ; Capra, A. ; Carruth, C. ; Cesar, C. L. ; Charlton, M. ; Christensen, A. ; Collister, R. ; A. Mathad, C. ; Eriksson, S. ; Evans, A. ; Evetts, N. ; Fajans, J. ; Friesen, T. ; Fujiwara, M. C. ; Gill, D. R. ; Grandemange, P. ; Granum, P. ; Hangst, J. S. ; Hardy, W. N. ; Hayden, M. E. ; Hodgkinson, D. ; Hunter, E. ; Isaac, C. A. ; Johnson, M. A. ; Jones, J. M. ; Jones, S. A. ; Jonsell, S. ; Khramov, A. ; Kurchaninov, L. ; Madsen, N. ; Maxwell, D. ; McKenna, J. T. K. ; Menary, S. ; Momose, T. ; Mullan, P. S. ; Munich, J. J. ; Olchanski, K. ; Olin, A. ; Peszka, J. ; Powell, A. ; Pusa, P. ; Rasmussen, C. Ø. ; Robicheaux, F. ; Sacramento, R. L. ; Sameed, M. ; Sarid, E. ; Silveira, D. M. ; So, C. ; Stutter, G. ; Tharp, T. D. ; Thompson, R. I. ; van der Werf, D. P. ; Wurtele, J. S. ; Shore, G. M. Precision Spectroscopy Of The Hyperfine Components Of The 1S–2S Transition In Antihydrogen. Nature Physics 2025, 21, 201–207.
Edwards, K. E. K. ; Wolf, M. E. ; Eltis, L. D. ; Ryan, K. S. Milm From Mildiomycin Biosynthesis Is An Oxygen-, Pyridoxal Phosphate-Dependent Arginine Hydroxylase. J. Biol. Chem. 2025, 110605.
Liu, B. ; Tang, Z. ; Huan, T. Adduct-Induced Variability In Tandem Mass Spectrometry. Analytical Chemistry 2025, 97, 17058–17066.
Higgins, M. A. ; Mirotadze, N. ; Shi, X. ; Hoffarth, E. R. ; Du, Y. - L. ; Ryan, K. S. Conversion Of A Heme-Dependent Dehydratase To A Piperazate Synthase Reveals The Role Of The Heme Propionate Group In N-N Bond-Formation. J. Am. Chem. Soc. 2025.
Wang, S. ; Li, C. ; Wang, S. ; Li, H. ; Chen, D. D. Y. Characterization Of The Specific Binding Between Aptamers And Cytochrome C With Pressure-Assisted Capillary Electrophoresis Frontal Analysis. ELECTROPHORESIS 2025, 46, 1461-1470.
Low, B. ; Zhao, T. ; Li, X. ; Huan, T. Machine Learning-Assisted Recognition Of Environmental Sulfur-Containing Chemicals In Non-Targeted Mass Spectrometry Analysis Of Inadequate Mass Resolution. ACS Environmental Au 2025, 5, 573–582.
Baker, D. V. ; W. Algar, R. ; Bizzotto, D. Immobilization Of Quantum Dot-Dna Conjugates Templated By Dna Self-Assembled Monolayers On Single-Crystal Gold Bead Electrodes Toward Advanced Sensing. ACS Applied Nano Materials 2025, 8.
Liu, Y. ; Wang, Z. ; Bi, W. ; Jin, C. ; Chen, D. D. Y. Deep Eutectic Solvent-Assisted Valorization Of Bamboo Biomass Into Functional Biochar For Sustainable Wastewater Treatment. Separation and Purification Technology 2025, 378, 134775.
Zhao, T. ; Low, B. ; Shen, Q. ; Wang, Y. ; Delgado, D. H. ; Chau, K. N. M. ; Pang, Z. ; Li, X. ; Xia, J. ; Li, X. ; Huan, T. Exposome-Scale Investigation Of Cl-/br-Containing Chemicals Using High-Resolution Mass Spectrometry, Multi-Stage Machine Learning, And Cloud Computing. Analytical Chemistry 2025.
Gu, T. ; Sun, J. ; Wang, S. ; Duan, X. ; Li, H. ; Liu, C. ; Chen, D. D. Y. Real-Time Monitoring Of Tea Volatiles Using Soft Ionization By Chemical Reaction In Transfer With An Online Sampling Interface. Green Analytical Chemistry 2025, 100290.
Zhou, G. Chris; Ma, T. ; Baker, D. V. ; Bizzotto, D. On The Carbodiimide Conjugation Of Dna To Mercapto-Undecanoic Acid-Terminated Sams On Gold: An Electrochemical And Fluorescence Imaging Study. Canadian Journal of Chemistry 2025.
Chenyakin, Y. ; Chen, D. D. Y. Determination Of Critical Micelle Concentration Of Ionic And Non-Ionic Surfactants By Streaming Potential Measurements. ELECTROPHORESIS 2025, 46, 990-997.
Lee, K. ; Su, X. ; Huan, T. Metabolites Are Not Genes – Avoiding The Misuse Of Pathway Analysis In Metabolomics. Nature Metabolism 2025, 7, 858–861.
Hagar, M. ; Kang, S. ; Andersen, R. J. ; Oh, D. - C. ; Ryan, K. S. Targeted Isolation Of Piperazate-Containing Molecules: Bioinformatics And Spectroscopy. Curr. Opin. Microbiol. 2025, 84, 102584.
Wharton, L. ; McNeil, S. W. ; Meeres, H. ; Zhang, D. ; Ingham, A. ; Merkens, H. ; Osooly, M. ; Rodríguez-Rodríguez, C. ; Bénard, F. ; Yang, H. Chelating [227Th]Th4+ For Peptide Receptor Radionuclide Therapy Of Neuroendocrine Tumors. Bioconjugate Chemistry 2025, 36.
LeSage, N. E. ; Baker, D. V. ; Davies, E. ; Wilkinson, D. P. ; Bizzotto, D. Influence Of Potential On The Adsorption Of A Material Binding Peptide On Au Via Eis And In-Situ Fluorescence Imaging. Electrochimica Acta 2025, 531, 146311.
Zhao, T. ; Shen, Q. ; Li, X. ; Huan, T. Iodofinder: Machine Learning-Guided Recognition Of Iodinated Chemicals In Nontargeted Lc-Ms/ms Analysis. Environmental Science & Technology 2025, 59, 4530–4539.
Semail, N. - F. ; Yahaya, N. ; Mohamed, A. Husaini; Chen, D. D. Y. ; Zain, N. Nadhirah M. Advances And Applications Of Capillary Electrophoresis Mass Spectrometry In Food Analysis: Strategies For Online And Offline Preconcentration. ELECTROPHORESIS 2025.
Mangahas, R. S. ; Bertram, A. K. ; Weis, D. ; Cullen, J. T. ; Maldonado, M. T. Spatiotemporal Trends Of Aerosol Provenance And Trace Metal Concentrations In The Northeast Subarctic Pacific Ocean. SCIENCE OF THE TOTAL ENVIRONMENT 2025, 971, 178885.