@article {WANG2024139004,
	title = {Strategies for using magnetic beads in enhanced deep eutectic solvent-mechanochemical extraction of natural products from orange peels},
	journal = {Food Chemistry},
	volume = {447},
	year = {2024},
	pages = {139004},
	abstract = {To address the challenges of low recovery, prolonged extraction times, and environmental pollution caused by toxic solvents in traditional extraction methods, magnetic bead-enhanced deep eutectic solvent mechanochemical extraction was developed for extracting natural products from orange peels. The extraction efficiencies of deep eutectic solvents were experimentally evaluated, and theoretical methods were used to guide solvent selection. Choline chloride-ethylene glycol demonstrated the highest efficiency under the optimal extraction conditions: a molar ratio of 1:2, no water content, a solid-liquid ratio of 0.08~g/mL, and an extraction time of 60~s. The synergy between the deep eutectic solvent and magnetic bead-enhanced the mechanochemical extraction efficiencies. The study also examined the effects of different magnetic bead types and orange peel powder particle sizes on extraction efficiency, finding that a 0.11~mm particle size combined with CIP@SiO2 yielded the best results. Overall, this study holds promise as an environmentally friendly and efficient extraction method.},
	keywords = {Deep eutectic solvents, Hydrogen bond donors and acceptors, Magnetic beads, Mechanochemical extraction, natural products, Orange peel},
	issn = {0308-8146},
	doi = {https://doi.org/10.1016/j.foodchem.2024.139004},
	url = {https://www.sciencedirect.com/science/article/pii/S0308814624006538},
	author = {Zhaoyang Wang and Wuxia Ge and Wentao Bi and David Da Yong Chen}
}
