| Title | Total synthesis of topopyrones B and D |
| Publication Type | Journal Article |
| Year of Publication | 2006 |
| Authors | Tan, JS, Ciufolini, MA |
| Journal | Organic Letters |
| Volume | 8 |
| Pagination | 4771-4774 |
| Date Published | Oct |
| Type of Article | Article |
| ISBN Number | 1523-7060 |
| Keywords | DIRECTED ORTHO METALATION, HYPOXYXYLERONE, TOPOISOMERASE-I INHIBITORS |
| Abstract | We describe a straightforward synthesis of topopyrones B and D, which are potent and selective inhibitors of topoisomerase I. The chemistry should be suitable for additional structure-activity relationship (SAR) work. |
| URL | <Go to ISI>://000241030900026 |
