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  3. Vanadium complexes as insulin mimetic agents: Coordination chemistry and in vivo studies of oxovanadium(IV) and dioxovanadate(V) complexes formed from naturally occurring chelating oxazolinate, thiazolinate, or picolinate units

Vanadium complexes as insulin mimetic agents: Coordination chemistry and in vivo studies of oxovanadium(IV) and dioxovanadate(V) complexes formed from naturally occurring chelating oxazolinate, thiazolinate, or picolinate units

TitleVanadium complexes as insulin mimetic agents: Coordination chemistry and in vivo studies of oxovanadium(IV) and dioxovanadate(V) complexes formed from naturally occurring chelating oxazolinate, thiazolinate, or picolinate units
Publication TypeJournal Article
Year of Publication1999
AuthorsMelchior, M, Thompson, KH, Jong, JM, Rettig, SJ, Shuter, E, Yuen, VG, Zhou, Y, McNeill, JH, Orvig, C
JournalInorganic Chemistry
Volume38
Pagination2288-2293
Date PublishedMay
Type of ArticleArticle
ISBN Number0020-1669
KeywordsBIS(MALTOLATO)OXOVANADIUM(IV), BMOV, CRYSTAL-STRUCTURE, DIABETIC RATS, GLUCOSE, NMR, SIDEROPHORE, SULFATE, SYSTEM, VANADATE
Abstract

{The synthesis and characterization of four complexes containing naturally occurring binding groups are reported: VO(pic)(2). H2O (Hpic = picolinic or pyridine-2-carboxylic acid), NH4[VO2(pic)(2)]. 2H(2)O, VO(oz)(2) (Hoz = 2-(2’- hydroxyphenyl)-2-oxazoline), and VO(thoz)(2) (Hthoz = 2-(2’-hydroxyphenyl)-2-thiazoline). The X-ray structures of [NH4[VO2(pic)(2)]. 2H(2)O, VO(oz)(2), and VO(thoz)(2) have been determined. Crystals of NH4[VO2(pic)(2)]. 2H(2)O (C12H12N3O6V . 2H(2)O) are monoclinic, space group Cc, a 10.347(2) Angstrom
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