| Title | Synthesis of 5-Amino-oxazole-4-carboxylates from α-Chloroglycinates. |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Zhang, J, Coqueron, P-Y, Vors, J-P, Ciufolini, MA |
| Journal | Organic Letters |
| Volume | 12 |
| Pagination | 3942 - 3945 |
| Date Published | 2010/// |
| ISBN Number | 1523-7060 |
| Keywords | aluminum Lewis acid cyclocondensation promoter, aminooxazole carboxylate prepn, cyanide ion chloroglycinate cyclocondensation aluminum Lewis acid, isonitrile chloroglycinate cyclocondensation aluminum Lewis acid |
| Abstract | Aluminum-based Lewis acids are effective promoters of the condensation of α-chloroglycinates with isonitriles or with cyanide ion, leading to the formation of 5-amino-oxazoles, e.g., I (R1 = Me, Ph; R2 = H, n-Bu, t-Bu, PhCH2). [on SciFinder(R)] |
