| Title | Syntheses of new ruthenium (II and III)-nitroimidazole complexes |
| Publication Type | Journal Article |
| Year of Publication | 2019 |
| Authors | Baird, IR, Skov, KA, James, BR |
| Journal | Inorganica Chimica Acta |
| Volume | 489 |
| Pagination | 100 - 107 |
| ISSN | 0020-1693 |
| Keywords | EF5, Etanidazole, Metronidazole, NITROIMIDAZOLES, Ru complexes |
| Abstract | Reactions of [Ru(DMF)6]Tf3 with 2- and 5-nitroimidzoles, including the so-called metronidazole (metro), etanidazole (SR2508), and EF5, of known biological value, have been used to synthesize: (a) hydrates of the three new RuII complexes [RuL6]Tf2,(L = 2NO2Im, 5NO2Im), and [Ru(2Me5NO2Im)5]Tf2; and (b) the two new RuIII complexes [Ru(DMF)4(SR2508)2]Tf3 and [Ru(DMF)2(EF5)2(EtOH)2]Tf3. Use of RuCl3٠3H2O as precursor generates hydrates of the complexes: fac- and mer-RuCl3(2NO2Im)3, mer-RuCl3(metro)3, RuCl3(SR2508)2(EtOH), RuCl3(EF5)2(EtOH), and trans-RuCl2(metro)4; a less well characterized complex is formulated RuCl3(2Me5NO2Im)3٠3CO2 containing what appears to be adsorbed CO2. |
| URL | http://www.sciencedirect.com/science/article/pii/S0020169318318577 |
| DOI | 10.1016/j.ica.2019.01.033 |
