Title | Substituted glycals as probes of glycosidase mechanisms |
Publication Type | Journal Article |
Year of Publication | 1996 |
Authors | Lai, ECK, Morris, SA, STREET, IP, Withers, SG |
Journal | BIOORGANIC & MEDICINAL CHEMISTRY |
Volume | 4 |
Pagination | 1929-1937 |
Date Published | NOV |
ISSN | 0968-0896 |
Abstract | {D-Glucal and a series of substituted derivatives have been tested as substrates, inhibitors and inactivators of the Agrobacterium faecalis beta-glucosidase in order to probe structure/function relationships in this enzyme. D-Glucal is shown to be a substrate (k(cat)=2.3 min(-1) |
DOI | 10.1016/S0968-0896(96)00175-7 |
