Research & Teaching Faculty

  1. Research & Teaching Faculty
  2. Department Publications
  3. Studies toward soraphen A: An aldol-metathesis avenue to the macrocyclic framework

Studies toward soraphen A: An aldol-metathesis avenue to the macrocyclic framework

TitleStudies toward soraphen A: An aldol-metathesis avenue to the macrocyclic framework
Publication TypeJournal Article
Year of Publication2006
AuthorsVincent, G, Mansfield, DJ, Vors, JP, Ciufolini, MA
JournalOrganic Letters
Volume8
Pagination2791-2794
Date PublishedJun
Type of ArticleArticle
ISBN Number1523-7060
KeywordsALPHA-HYDROXYALLYLATION, ANTIFUNGAL, CARBONYL-COMPOUNDS, CHIRAL ALDEHYDES, ENANTIOSELECTIVE SYNTHESIS, GLIDING BACTERIA, MACROLIDE, OLEFIN METATHESIS, ORGANIC-SYNTHESIS, SILYL ETHERS, STEREOSELECTIVE SYNTHESIS
Abstract

We describe a convergent approach to soraphen A, 1, that involves coupling of two fragments by an aldol condensation - olefin metathesis sequence. This route permits rapid access to congeners of 1.
URL<Go to ISI>://000238284500034