| Title | Selective reactivity of electron-rich aryl iodides in the Heck arylation of disubstituted alkenes catalyzed by palladium-arylurea complexes |
| Publication Type | Journal Article |
| Year of Publication | 2013 |
| Authors | Smith, MR, Jang, YJin, Kim, JYun, Ciufolini, MA |
| Journal | TETRAHEDRON |
| Volume | 69 |
| Pagination | 10139-10151 |
| Date Published | NOV 25 |
| ISSN | 0040-4020 |
| Abstract | A catalyst consisting of 1 mol % of the 1:2 complex of Pd(OAc)(2) with N-(4-carbethoxyphenyl)urea promotes the Heck arylation of 2- or 3-substituted, conjugated esters, nitriles, aldehydes, and ketones (an uncharacteristically broad range of substrates), but only with electron-rich aryl iodides (an uncharacteristically narrow range of halides). (C) 2013 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tet.2013.09.019 |
