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Ruthenium(III) maltolato-nitroimidazole complexes: Synthesis and biological activity

TitleRuthenium(III) maltolato-nitroimidazole complexes: Synthesis and biological activity
Publication TypeJournal Article
Year of Publication2006
AuthorsKennedy, DC, Wu, A, Patrick, BO, James, BR
JournalJournal of Inorganic Biochemistry
Volume100
Pagination1974-1982
Date PublishedDec
ISBN Number0162-0134
Abstract

{The Ru(III) metronidazole-maltolato and -ethylmaltolato complexes, trans-[R-uL(2)(metro)(2)]CF3SO3 (L = ma (1a) or etma (1b)), have been synthesized and tested for potential anti-tumour activity against the human breast cancer cell line MDA-MB-435S using a so-called MTT assay in phosphate-buffered saline; ma = 3-hydroxy-2-methylpyran-4-onato

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