| Title | Quantitative assay fdr epinephrine in dental anesthetic solutions by capillary electrophoresis |
| Publication Type | Journal Article |
| Year of Publication | 1998 |
| Authors | Britz-McKibbin, P, Kranack, AR, Paprica, A, Chen, DDY |
| Journal | Analyst |
| Volume | 123 |
| Pagination | 1461-1463 |
| Date Published | Jul |
| Type of Article | Article |
| ISBN Number | 0003-2654 |
| Keywords | analyte focusing, capillary electrophoresis, CHROMATOGRAPHY, dental anesthetic solutions, EPINEPHRINE, INJECTION, LIDOCAINE, SAMPLES, STACKING, TETRACAINE, ZONE ELECTROPHORESIS |
| Abstract | A simple and robust method for the separation and quantification of epinephrine in dental anesthetic solutions was developed. The method allows the direct injection of high salt solutions without Sample pre-treatment. Large sample plugs (5.7% of the total capillary length) are used for epinephrine determination by selective analyte focusing in capillary electrophoresis, The concentration detection limit for epinephrine is about 5.0 x 10(-7) M (90 ng ml(-1)) with a commercial UV detector. The separation protocol was validated in terms of its precision, linearity, accuracy and specificity. |
| URL | <Go to ISI>://000074920200007 |
