| Title | Pyrrole synthesis catalyzed by AgOTf or cationic Au(I) complexes |
| Publication Type | Journal Article |
| Year of Publication | 2006 |
| Authors | Harrison, TJ, Kozak, JA, Corbella-Pane, M, Dake, GR |
| Journal | Journal of Organic Chemistry |
| Volume | 71 |
| Pagination | 4525-4529 |
| Date Published | Jun |
| Type of Article | Article |
| ISBN Number | 0022-3263 |
| Keywords | 2-PROPYNYL-1, 3-DICARBONYL COMPOUNDS, AMINATION/ANNULATION REACTIONS, C-H BONDS, CARBOXYLIC-ACIDS, DERIVATIVES, EFFICIENT SYNTHESIS, FURANS, ONE-POT, PYRROLES, REGIOSELECTIVE SYNTHESIS, SUBSTITUTED |
| Abstract | Either silver trifluoromethanesulfonate or a mixture of gold( I) chloride, silver trifluoromethanesulfonate, and triphenylphosphine catalyze the formation of pyrroles from substituted beta-alkynyl ketones and amines. The reactions proceed by using 5 mol % of catalyst with yields of isolated pyrroles ranging from 13% to 92%. Sixteen examples are used to compare the effectiveness of each catalyst. |
| URL | <Go to ISI>://000238029300023 |
