| Title | Nucleophilic additions of lactam-derived enol triflates to aldehydes mediated by nickel(II) and chromium(II) salts |
| Publication Type | Journal Article |
| Year of Publication | 2004 |
| Authors | Easton, LP, Dake, GR |
| Journal | Canadian Journal of Chemistry-Revue Canadienne De Chimie |
| Volume | 82 |
| Pagination | 139-144 |
| Date Published | Feb |
| Type of Article | Article |
| ISBN Number | 0008-4042 |
| Keywords | BOND FORMATIONS, BREVETOXIN-B, carbonyl addition, CATALYSIS, chromium(II) chloride, CONSTRUCTION, CYCLIZATION, DERIVATIVES, DYNEMICIN-A, ENANTIOSELECTIVE, lactam-derived enol triflate, LEPADIN B, NI(II)/CR(II)-MEDIATED COUPLING REACTION, nickel(II) chloride, TOTAL-SYNTHESIS |
| Abstract | Enol trifluoromethanesulfonates (triflates) derived from N-protected lactams undergo nickel(II)-chloride- and chromium(II)-chloride-promoted carbonyl additions to aldehydes. The yields of this process range from 42%-84%. |
| URL | <Go to ISI>://000220138500010 |
