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SYNTHESIS OF 2-DEOXY-2-[F-18]-FLUORO-BETA-MANNOSYL [F-18] FLUORIDE AS A POTENTIAL IMAGING PROBE FOR GLYCOSIDASES

TitleSYNTHESIS OF 2-DEOXY-2-[F-18]-FLUORO-BETA-MANNOSYL [F-18] FLUORIDE AS A POTENTIAL IMAGING PROBE FOR GLYCOSIDASES
Publication TypeJournal Article
Year of Publication1992
AuthorsMCCARTER, JD, ADAM, MJ, Withers, SG
JournalJOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
Volume31
Pagination1005-1009
Date PublishedDEC
ISSN0362-4803
Abstract

The mechanism-based glycosidase inhibitor 2-deoxy-2-{[}F-18]-fluoro-beta-mannosyl {[}F-18]-fluoride was synthesized and its covalent binding to Agrobacterium beta-glucosidase was demonstrated in vitro.

DOI10.1002/jlcr.2580311207