| Title | ``Extreme'' Ugi Reactions With Some Complex alpha-Amino Acids |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Turner, CDylan, Ciufolini, MA |
| Journal | ORGANIC LETTERS |
| Volume | 14 |
| Pagination | 4970-4973 |
| Date Published | SEP 21 |
| ISSN | 1523-7060 |
| Abstract | The Ti(IV)-catalyzed Ugi condensation of alpha-amino acids with electron-rich aromatic aldehydes performs adequately even with sterically demanding alpha-amino carboxylate salts. The reaction occurs diastereoselectively, in some cases with virtually complete diastereoselectivity. A stereochemical rationale for the reaction is proposed. |
| DOI | 10.1021/ol302379a |
