Research & Teaching Faculty

NaH mediated isomerisation–allylation reaction of 1,3-substituted propenols

TitleNaH mediated isomerisation–allylation reaction of 1,3-substituted propenols
Publication TypeJournal Article
Year of Publication2013
AuthorsJohnston, AJS, McLaughlin, MG, Reid, JP, Cook, MJ
JournalOrg. Biomol. Chem.
Volume11
Pagination7662-7666
Abstract

A base mediated isomerisation–allylation protocol of 1{,}3-disubstituted propenols has been established. The use of diaryl and aryl-silyl substrates is reported alongside the use of substituted allyl bromides. Mechanistic experiments have also been conducted to elucidate the reaction pathway.

URLhttp://dx.doi.org/10.1039/C3OB41857J
DOI10.1039/C3OB41857J