|Title||THE METHYLATION OF ARSENATE BY A MARINE ALGA POLYPHYSA-PENICULUS IN THE PRESENCE OF L-METHIONINE-METHYL-D(3)|
|Publication Type||Journal Article|
|Year of Publication||1994|
|Authors||Cullen, WR, Li, H, Pergantis, SA, Eigendorf, GK, Harrison, LG|
|Type of Article||Article|
|Keywords||ALGAE, arsenic, COMPOUNDS, CONTAINING RIBOFURANOSIDES, ENVIRONMENT, GENERATION GAS CHROMATOGRAPHY MASS SPECTROMETRY (HG-GC-MS), hydride, IDENTIFICATION, KELP ECKLONIA-RADIATA, L-METHIONINE-METHYL-D(3), METHYLARSENIC COMPOUNDS, METHYLATION, NATURAL-WATERS, ORGANOARSENIC, REDUCTION, SPECIATION, SPECTROMETRY|
Polyphysa peniculus growing in artificial seawater methylates arsenate to produce a dimethylarsenic derivative, probably dimethylarsinate. When L-methionine-methyl-d3 is added to the culture the CD3 label is incorporated intact in the dimethylarsenic compound to a considerable extent, indicating that S-adenosylmethionine, or some related sulphonium compound, is involved in the biological methylation. Conclusive evidence of the CD3 incorporation was provided by using a specially developed hydride generation-gas chromatography-mass spectrometry methodology.
|URL||<Go to ISI>://A1994NC95900016|