| Title | Glycosphingolipid synthesis employing a combination of recombinant glycosyltransferases and an endoglycoceramidase glycosynthase |
| Publication Type | Journal Article |
| Year of Publication | 2011 |
| Authors | Rich, JR, Cunningham, A-M, Gilbert, M, Withers, SG |
| Journal | CHEMICAL COMMUNICATIONS |
| Volume | 47 |
| Pagination | 10806-10808 |
| ISSN | 1359-7345 |
| Abstract | Glycosynthase mutants of Rhodococcus sp. endo-glycoceramidase II efficiently synthesize complex glycosphingolipids. Glycosyl fluoride donors may be assembled via sequential glycosyltransferase-catalysed glycosylation of lactosyl fluoride. Alternatively, lactosyl fluoride may be coupled to sphingosine prior to subsequent glycosylation steps. |
| DOI | 10.1039/c1cc13885e |
