| Title | A glucosamine dipicolylamine conjugate of Tc-99m(I) and Re-186(I) for use in imaging and therapy |
| Publication Type | Journal Article |
| Year of Publication | 2005 |
| Authors | Storr, T, Fisher, CL, Mikata, Y, Yano, S, Adam, MJ, Orvig, C |
| Journal | Dalton Transactions |
| Pagination | 654-655 |
| Type of Article | Article |
| ISBN Number | 1477-9226 |
| Keywords | ACID, BIOMOLECULES, COMPLEXES, RADIOPHARMACEUTICALS, RE |
| Abstract | The synthesis and metal complexation of a glucosamine-appended 2,2’-dipicolylamine ligand to the tricarbonyls of Tc-99m and Re-186 is described; the ligand was found to bind in a tridentate fashion with the glucosamine function remaining pendant, and the Tc-99m complex was found to exhibit exceptional stability towards in vitro ligand exchange experiments. |
| URL | <Go to ISI>://000226844900003 |