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GLACIASTEROL-A AND GLACIASTEROL-B, 9,11-SECOSTEROIDS FROM THE MARINE SPONGE APLYSILLA-GLACIALIS

TitleGLACIASTEROL-A AND GLACIASTEROL-B, 9,11-SECOSTEROIDS FROM THE MARINE SPONGE APLYSILLA-GLACIALIS
Publication TypeJournal Article
Year of Publication1992
AuthorsPika, J, Tischler, M, Andersen, RJ
JournalCanadian Journal of Chemistry-Revue Canadienne De Chimie
Volume70
Pagination1506-1510
Date PublishedMay
Type of ArticleArticle
ISBN Number0008-4042
KeywordsSTEROLS
Abstract

The glaciasterols, a family of cytotoxic 9,11-secosteroids, have been isolated from extracts of the northeastern Pacific sponge Aplysilla glacialis. The structures of glaciasterol A (2) and glaciasterol B (3) were elucidated by a combination of spectroscopic analysis and chemical interconversions on the native steroid 2 and the diacetate 5 of glaciasterol B (3).
URL<Go to ISI>://A1992JL87000028