|Title||An effective synthetic route to EF5|
|Publication Type||Journal Article|
|Year of Publication||1998|
|Authors||Baird, IR, Skov, KA, James, BR, Rettig, SJ, Koch, CJ|
|Type of Article||Article|
|Keywords||ANTIBODIES, BINDING, CELLS, COMPLEXES, CRYSTAL, HYPOXIA, TUMORS|
EF5 (a 2-nitroimidazole containing an N-(pentafluoropropyl) acetamide substituent) is a very sensitive probe for quantifying the amount of hypoxia within cells; a much improved, short step, synthetic procedure is described for EF5, whose X-ray structure is also presented.
|URL||<Go to ISI>://000075780100021|