MWF 9-10 am, C124
Parisa Mehrkhodavandi
Office hours: B354, Thursdays 4-6 pm
Recommended Textbooks:
Elschenbroich and Salzer; Organometallics: A Concise Introduction
Crabtree; The Organometallic Chemistry of the Transition Metals
References Books:
Greenwood and Earnshaw; Chemistry of the Elements
Cotton and Wilkinson; Advanced Inorganic Chemistry
Collman and Hegadus and ...; Principles and Applications of Organotransition
Metal Chemistry
Spessard and Miessler; Organometallic Chemistry
Journals:
Journal of the American Chemical Society
Organometallics
Angewandte Chemie International Edition
Main Group Elements
Introduction
- General survey (i.e. introduction, nomenclature, stabilities of M-C bonds etc.)
- Methods of formation of metal-carbon bonds of the main group elements
The Alkali Metals
- Organolithium compounds, metallation reactions, electron-deficient bonding
- Sodium and the heavier alkalis, substitution and addition compounds
The Group 2 and 12 Elements
- Group trends, coordination complexes, methylene transfer processes, stereochemical nonrigidity
The Group 13 elements
- Hydroboration and hydroalumination, heterocyclic compounds, carboranes, coordination complexes, catalytic properties, lower valence states of the heavier elements
The Group 14 and 15 elements
- Their uses as transmetallating and reducing agents, heterocyclic compounds, silicone polymers, complexes containing metal-metal bonds
- Group trends, both formal valence states III and V, complexes containing metal-metal bonds
** Mid-term examination **
Transition Elements
Introduction
- Classification of ligands, the 18-electron rule and its applicability, molecular orbital description of bonding in organometallic complexes
σ-Donor Ligands
- Metal alkyls, aryls and hydrides
- Selected properties, σ-complexes
σ-Donor / π-Acceptor Ligands
- Metal complexes of CO, RNC, CS and NO
- Bonding and reactivity
π-Bound Ligands
- Alkene and alkyne complexes, allyl complexes
- Cyclopentadienyl complexes, arene complexes
- Properties, reactivity and bonding
Metal-Carbon Multiple Bonds
- Carbenes, alkylidenes, alkylidynes
- Reactions, metathesis and catalysis
Organometallic Reactions
- Ligand substitution
- Oxidative addition/reductive elimination
- Insertion and elimination
- Nucleophilic/electrophilic reactions
Selected Topics
- further applications in organic synthesis / catalysis
- C-H activation
- Organo-lanthanide/actinide chemistry
- Bioorganometallic chemistry
- Heterogeneous organometallic catalysis
Marks Breakdown:
| Midterm | 20 |
| Paper (topic to be discussed later) | 20 |
| PS/Participation (discussion of problem sets) | 10 |
| Final | 50 |
| Total | 100 |