Course Level:
Third Year
Academic Year:
2024/2025
Instructor: Dr. John Sherman
Office: A243
604-822-2305
sherman@chem.ubc.ca
Course Outline (Subject to Change):
A. Amino acids and peptides (3-4 weeks)
- Amino acids-structure, acid/base properties, review of electronic effects
- Reactions of amino acids
- Peptides-structure determination, synthesis of peptides
B. Carbohydrates (3-4 weeks)
- Monosaccharides-structure, conformations (review)
- Reactions of monosaccharides
- Protecting groups
- Glycoside couplings
- Oligosaccharide structures
C. Organophosphate esters (1-2 weeks)
- Acid/base properties, hydrolysis mechanisms, synthesis of
- DNA/RNA synthesis
D. Pyridoxal phosphate and Thiamin (1-2 weeks)
- Structure, function
- Mechanisms of catalytic reactions