Please note: The following outline is subject to change - it may reflect a previous term's offering of the course, ie. last year (2025-2026). Please check again soon for any update - this note will not appear once the following outline has been updated / finalized.
Diffusion and Transport Phenomena
• Diffusion in one, two, and three dimensions
Random walk (Brownian motion)
Fick's laws
Stokes-Einstein equation and molecular shapes
• Electrophoresis
• Sedimentation
Svedberg equation
Equilibrium and velocity sedimentation
• Mass spectrometry
Macromolecular Interactions
• Thermodynamics and kinetics of macromolecular binding
• Analytical methods
Biochemical/genetic approaches
Spectroscopy (absorbance, fluorescence, circular/linear dichroism)
Isothermal titration calorimetry
Surface plasmon resonance
• Structure and dynamics
• Allostery and co-operativity
• Single molecule approaches