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Boneratamides A-C, new sesquiterpenoids isolated from the marine sponge Axinyssa aplysinoides

TitleBoneratamides A-C, new sesquiterpenoids isolated from the marine sponge Axinyssa aplysinoides
Publication TypeJournal Article
Year of Publication2004
AuthorsWilliams, DE, Patrick, BO, Tahir, A, Van Soest, R, Roberge, M, Andersen, RJ
JournalJournal of Natural Products
Volume67
Pagination1752-1754
Date PublishedOct
Type of ArticleArticle
ISBN Number0163-3864
KeywordsAGENT, ANALOGS, BINDING, HEMIASTERLIN, NATURAL-PRODUCTS, PACLITAXEL, TUBULIN
Abstract

Three new sesquiterpenoids, boneratamides A (1)-C (3), have been isolated as their methyl esters 4-6 from extracts of the marine sponge Axinyssa aplysinoides collected in Indonesia. The structures of methyl esters 4-6 were elucidated by analysis of spectroscopic data and confirmed by single-crystal X-ray diffraction analysis of 4.
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