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Ambewelamides A and B, antineoplastic epidithiapiperazinediones isolated from the lichen Usnea sp

TitleAmbewelamides A and B, antineoplastic epidithiapiperazinediones isolated from the lichen Usnea sp
Publication TypeJournal Article
Year of Publication1998
AuthorsWilliams, DE, Bombuwala, K, Lobkovsky, E, De Silva, ED, Karunaratne, V, Allen, TM, Clardy, J, Andersen, RJ
JournalTetrahedron Letters
Volume39
Pagination9579-9582
Date PublishedDec
Type of ArticleArticle
ISBN Number0040-4039
Keywordsmicrotubules, TAXOL
Abstract

Two potently cytotoxic epidithiapiperazinediones, ambewelamides A (1) and B (2), have been isolated from the lichen Usnea sp. collected in Sri Lanka. The structures were determined by a combination of X-ray crystallographic and spectroscopic analyses. (C) 1998 Elsevier Science Ltd. All rights reserved.
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