| Title | (55)Cobalt complexes with pendant carbohydrates as potential PET imaging agents |
| Publication Type | Journal Article |
| Year of Publication | 2007 |
| Authors | Ferreira, CL, Lapi, S, Steele, J, Green, DE, Ruth, TJ, Adam, MJ, Orvig, C |
| Journal | Applied Radiation and Isotopes |
| Volume | 65 |
| Pagination | 1303-1308 |
| Date Published | Dec |
| ISBN Number | 0969-8043 |
| Abstract | Bis-ligand cobalt(II) complexes of four 3-hydroxy-4-pyridinone ligands with pendant carbohydrates were synthesized and examined for their potential as radiopharmaceuticals. Non-radioactive complexes were prepared on the macroscopic scale and characterized by elemental analysis, mass spectrometry, IR and UV/visible spectroscopy. Facile radiolabeling produced the (CO)-C-55 complexes in high radiochemical yields (> 95%). Identification of the radiolabeled compounds was accomplished by HPLC comparison with the corresponding non-radioactive complexes. (c) 2007 Elsevier Ltd. All rights reserved. |
| URL | <Go to ISI>://000251536900001 |
