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Scalarane-Based Sesterterpenoid RCE-Protease Inhibitors Isolated from the Indonesian Marine Sponge Carteriospongia foliascens

TitleScalarane-Based Sesterterpenoid RCE-Protease Inhibitors Isolated from the Indonesian Marine Sponge Carteriospongia foliascens
Publication TypeJournal Article
Year of Publication2009
AuthorsWilliams, DE, Hollander, I, Feldberg, L, Frommer, E, Mallon, R, Tahir, A, Van Soest, R, Andersen, RJ
JournalJournal of Natural Products
Volume72
Pagination1106-1109
Date PublishedJun
Type of ArticleArticle
ISBN Number0163-3864
KeywordsPHYLLOSPONGIA
Abstract

Two new 20,24-bishomo-25-norscalaranes, compounds 1 and 2, and two new and two known 20,24-bishomoscalaranes, compounds 3-6, have been isolated from the Indonesian marine sponge Carteriospongia foliascens. The structures of 1-6 were determined by spectroscopic analysis. Compounds 1 and 3-6 inhibit RCE-protease activity.

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