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Platinum(II)-catalyzed cyclizations forming quaternary carbon centers, using enesulfonamides, enecarbamates, or enamides as nucleophiles

TitlePlatinum(II)-catalyzed cyclizations forming quaternary carbon centers, using enesulfonamides, enecarbamates, or enamides as nucleophiles
Publication TypeJournal Article
Year of Publication2007
AuthorsHarrison, TJ, Patrick, BO, Dake, GR
JournalOrganic Letters
Volume9
Pagination367-370
Date PublishedJan
ISBN Number1523-7060
Abstract

Cyclic enesulfonamides, enecarbamates, or enamides tethered to an alkyne cyclize readily with use of platinum(II) chloride. This reaction generates quaternary-substituted carbon centers within simple spiro-fused or more complex tri- and tetracyclic heterocyclic ring systems. The yields for this process range from 50% to 83%.

URL<Go to ISI>://000243389000050