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Pd-arylurea complexes for the Heck arylation of crotonic and cinnamic substrates

TitlePd-arylurea complexes for the Heck arylation of crotonic and cinnamic substrates
Publication TypeJournal Article
Year of Publication2013
AuthorsSmith, MR, Kim, JYun, Ciufolini, MA
JournalTETRAHEDRON LETTERS
Volume54
Pagination2042-2045
Date PublishedAPR 17
ISSN0040-4039
Abstract

A catalyst consisting of the 1:2 complex of Pd(OAc)(2) (1 mol %) with N-(4-carbethoxy)-phenylurea promotes the Heck arylation of a range of crotonic and cinnamic substrates, including aldehydes, ketones, esters, and nitriles, with electron-rich-but not electron-deficient-aryl iodides. (c) 2013 Elsevier Ltd. All rights reserved.

DOI10.1016/j.tetlet.2013.01.077