|Title||Latonduines A and B, new alkaloids isolated from the marine sponge Stylissa carteri: Structure elucidation, synthesis, and biogenetic implications|
|Publication Type||Journal Article|
|Year of Publication||2003|
|Authors||Linington, RG, Williams, DE, Tahir, A, Van Soest, R, Andersen, RJ|
|Type of Article||Article|
|Keywords||COMPOUND, DEBROMOHYMENIALDISINE, HYMENIALDISINE, INHIBITION, STEVENSINE|
Latonduines A (6) and B (7), two new alkaloids with unprecedented heterocyclic skeletons, have been isolated from the Indonesian marine sponge Stylissa carted. The structures of the, latonduines were elucidated by analysis of spectroscopic data and confirmed by the total synthesis of latonduine A (6). It is proposed that ornithine is the biogenetic precursor to the aminopyrimidine fragment of the latonduines.
|URL||<Go to ISI>://000184257600039|