Research & Faculty

Default Header Image

Determination of shapes and maximums of analyte peaks based on solute mobilitiess in capillary electrophoresis

TitleDetermination of shapes and maximums of analyte peaks based on solute mobilitiess in capillary electrophoresis
Publication TypeJournal Article
Year of Publication2004
AuthorsFang, N, Ting, E, Chen, DDY
JournalAnalytical Chemistry
Volume76
Pagination1708-1714
Date PublishedMar
Type of ArticleArticle
ISBN Number0003-2700
KeywordsDISPERSION, DYNAMIC COMPLEXATION, FLOW, MIGRATION BEHAVIOR, NUMERICAL-SIMULATION, pressure, QUANTITATIVE DESCRIPTION, SEPARATIONS, ZONE-ELECTROPHORESIS
Abstract

In capillary electrophoresis, the relative orders of mobilities of analyte, additive, and the complex formed determine the analyte peak shape in a way similar to the way the binding isotherms determine the peak shapes in chromatography. The three mobilities allow six possible orders; each produces a characteristic peak shape in CE. Equations describing the analyte migration in a CE system with the presence of mobility-changing additives can be implemented into computer programs to predict the migration times of the analyte peak maximums, and the predicted migration times agree well with the experimental results.

URL<Go to ISI>://000220225200023