@article {2438, title = {A DNAzyme with Three Protein-Like Functional Groups: Enhancing Catalytic Efficiency of M2+-Independent RNA Cleavage}, journal = {Chembiochem}, volume = {10}, number = {12}, year = {2009}, note = {ISI Document Delivery No.: 487MWTimes Cited: 5Cited Reference Count: 76Hollenstein, Marcel Hipolito, Christopher J. Lam, Curtis H. Perrin, David M.}, month = {Aug}, pages = {1988-1992}, type = {Article}, keywords = {BEACON SENSOR, biology, CLEAVING DNA ENZYME, CYTOSOLIC FREE MAGNESIUM, DEOXYRIBOZYMES, DNAzymes, enzyme catalysis, EVOLUTION, HAIRPIN RIBOZYME, HIGH-DENSITY, IN-VITRO SELECTION, ION, nucleic acids, NUCLEIC-ACIDS, RNAse A mimics, synthetic}, isbn = {1439-4227}, url = {://000269279700012}, author = {Hollenstein, M. and Hipolito, C. J. and Lam, C. H. and Perrin,David M.} } @article {2104, title = {A highly selective DNAzyme sensor for mercuric ions}, journal = {Angewandte Chemie-International Edition}, volume = {47}, number = {23}, year = {2008}, note = {ISI Document Delivery No.: 308BXTimes Cited: 46Cited Reference Count: 93Hollenstein, Marcel Hipolito, Christopher Lam, Curtis Dietrich, David Perrin, David M.}, pages = {4346-4350}, type = {Article}, keywords = {AQUEOUS-MEDIA, BASE-PAIRS, CATALYTIC BEACON, DIVALENT, DNA, ENGINEERED ALLOSTERIC RIBOZYMES, enzyme catalysis, GOLD NANOPARTICLES, IN-VITRO SELECTION, mercury, MERR FAMILY PROTEINS, METAL-IONS, nucleic acids, NUCLEIC-ACID ENZYMES, SENSOR, sensors, TURN-ON}, isbn = {1433-7851}, url = {://000256364400014}, author = {Hollenstein, M. and Hipolito, C. and Lam, C. and Dietrich, D. and Perrin,David M.} } @article {5031, title = {Artificial nucleases}, journal = {Chembiochem}, volume = {2}, number = {10}, year = {2001}, note = {ISI Document Delivery No.: 479NGTimes Cited: 54Cited Reference Count: 25}, month = {Oct}, pages = {735-740}, type = {Article}, abstract = {The oxidation of DNA and RNA provides a facile approach for investigating the interaction of nucleic acids wit proteins and oligonucleotides In this article, we have outlined our understanding of the mechanism of DNA scission by 1,10-phenanthroline-copper(I) in the presence of hydrogen peroxide. We also discuss results obtained by using 1,10-phenanthroline - oligonucleotide conjugates in probing the size of the transcriptionally active open complex. Finally, we outline an effective method for converting DNA-binding proteins into site-specific modification agents by using 1,10-phenanthroline-copper(I).}, keywords = {1, 10-PHENANTHROLINE-COPPER ION, chemical, COLI RNA-POLYMERASE, COMPLEX, copper, DNA, DNA cleavage, DNA recognition, ESCHERICHIA-COLI, NUCLEASE, nucleic acids, OLIGONUCLEOTIDES, PROTEIN, SITE-SPECIFIC NUCLEASE, TRANSCRIPTION INITIATION}, isbn = {1439-4227}, url = {://000171410000003}, author = {Chen, C. H. B. and Milne, L. and Landgraf, R. and Perrin,David M. and Sigman, D. S.} }