@article {doi:10.1002/anie.201709532,
	title = {An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy},
	journal = {Angewandte Chemie International Edition},
	volume = {56},
	number = {46},
	year = {2017},
	pages = {14712-14717},
	abstract = {Abstract The 18-membered macrocycle H2macropa was investigated for 225Ac chelation in targeted alpha therapy (TAT). Radiolabeling studies showed that macropa, at submicromolar concentration, complexed all 225Ac (26 kBq) in 5 min at RT. [225Ac(macropa)]+ remained intact over 7 to 8 days when challenged with either excess La3+ ions or human serum, and did not accumulate in any organ after 5 h in healthy mice. A bifunctional analogue, macropa-NCS, was conjugated to trastuzumab as well as to the prostate-specific membrane antigen-targeting compound RPS-070. Both constructs rapidly radiolabeled 225Ac in just minutes at RT, and macropa-Tmab retained >99 \% of its 225Ac in human serum after 7 days. In LNCaP xenograft mice, 225Ac-macropa-RPS-070 was selectively targeted to tumors and did not release free 225Ac over 96 h. These findings establish macropa to be a highly promising ligand for 225Ac chelation that will facilitate the clinical development of 225Ac TAT for the treatment of soft-tissue metastases.},
	keywords = {actinium, CANCER, Chelates, macrocycles, RADIOPHARMACEUTICALS},
	doi = {10.1002/anie.201709532},
	url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201709532},
	author = {Thiele, Nikki A. and Brown, Victoria and Kelly, James M. and Amor-Coarasa, Alejandro and Jermilova, Una and MacMillan, Samantha N. and Nikolopoulou, Anastasia and Ponnala, Shashikanth and Ramogida, Caterina F. and Robertson, Andrew K. H. and Rodr{\'\i}guez-Rodr{\'\i}guez, Cristina and Schaffer, Paul and Williams Jr., Clarence and Babich, John W. and Radchenko, Valery and Wilson, Justin J.}
}
@article {1265,
	title = {A glucosamine dipicolylamine conjugate of Tc-99m(I) and Re-186(I) for use in imaging and therapy},
	journal = {Dalton Transactions},
	number = {4},
	year = {2005},
	note = {ISI Document Delivery No.: 895EYTimes Cited: 32Cited Reference Count: 16},
	pages = {654-655},
	type = {Article},
	abstract = {The synthesis and metal complexation of a glucosamine-appended 2,2{\textquoteright}-dipicolylamine ligand to the tricarbonyls of Tc-99m and Re-186 is described; the ligand was found to bind in a tridentate fashion with the glucosamine function remaining pendant, and the Tc-99m complex was found to exhibit exceptional stability towards in vitro ligand exchange experiments.},
	keywords = {ACID, BIOMOLECULES, COMPLEXES, RADIOPHARMACEUTICALS, RE},
	isbn = {1477-9226},
	url = {<Go to ISI>://000226844900003},
	author = {Storr, T. and Fisher, C. L. and Mikata, Y. and Yano, S. and Adam,Michael J. and Orvig, Chris}
}
@article {1265,
	title = {A glucosamine dipicolylamine conjugate of Tc-99m(I) and Re-186(I) for use in imaging and therapy},
	journal = {Dalton Transactions},
	number = {4},
	year = {2005},
	note = {ISI Document Delivery No.: 895EYTimes Cited: 32Cited Reference Count: 16},
	pages = {654-655},
	type = {Article},
	abstract = {The synthesis and metal complexation of a glucosamine-appended 2,2{\textquoteright}-dipicolylamine ligand to the tricarbonyls of Tc-99m and Re-186 is described; the ligand was found to bind in a tridentate fashion with the glucosamine function remaining pendant, and the Tc-99m complex was found to exhibit exceptional stability towards in vitro ligand exchange experiments.},
	keywords = {ACID, BIOMOLECULES, COMPLEXES, RADIOPHARMACEUTICALS, RE},
	isbn = {1477-9226},
	url = {<Go to ISI>://000226844900003},
	author = {Storr, T. and Fisher, C. L. and Mikata, Y. and Yano, S. and Adam,Michael J. and Orvig, Chris}
}
@article {1208,
	title = {Group 13 and lanthanide complexes with mixed O,S anionic ligands derived from maltol},
	journal = {Inorganic Chemistry},
	volume = {44},
	number = {8},
	year = {2005},
	note = {ISI Document Delivery No.: 916GWTimes Cited: 23Cited Reference Count: 61},
	month = {Apr},
	pages = {2666-2677},
	type = {Article},
	abstract = {Four mixed O,S binding ligand precursors derived from maltol (3-hydroxy-2-methyl-4-pyrone) have been chelated to gallium(III), indium(III), and lanthanide(III) ions to yield a series of metal complexes. The four ligand precursors include two pyranthiones, 3-hydroxy-2-methyl-4-pyranthione, commonly known as thiomaltol (Htma), and 2-ethyl-3-hydroxy-4-pyranthione, commonly known as ethylthiornaltol (Hetma), and two pyridinethiones, 3-hydroxy-2-methyl-4(H)-pyridinethione (Hmppt) and 3-hydroxy-1,2-dimethyl-4-pyridinethione (Hdppt). Dimeric forms of the pyridinethiones, Hmppt dimer and Hdppt dimer, were also isolated and characterized. Complete characterization of the monomeric organic compounds is reported including acidity constants and crystal structures of Htma, Hetma, and Hdppt dimer. Reacting the four monomeric ligand precursors with Ga3+ and In3+ ions yielded new tris(bidentate ligand) complexes. X-ray-quality crystals of the fac isomer of Ga(tma)(3) were also obtained. New complexes with a range of anthanicles (Ln(3+)) were also synthesized with the two pyranthiones, Htma and Hetma. The synthesis reactions yielded complexes of the type LnL(3)center dot xH(2)O and LnL(2)(OH)center dot xH(2)O, as indicated by elemental analysis and spectroscopic evidence such as mass spectral data and IR and NMR spectra.},
	keywords = {ACID, aluminum, CHELATE COMPLEXES, CHEMISTRY, CRYSTAL-STRUCTURE, DIAGNOSTIC-TOOLS, gallium, indium, METAL-COMPLEXES, RADIOPHARMACEUTICALS},
	isbn = {0020-1669},
	url = {<Go to ISI>://000228374400017},
	author = {Monga, V. and Patrick, B. O. and Orvig, Chris}
}
@article {1208,
	title = {Group 13 and lanthanide complexes with mixed O,S anionic ligands derived from maltol},
	journal = {Inorganic Chemistry},
	volume = {44},
	number = {8},
	year = {2005},
	note = {ISI Document Delivery No.: 916GWTimes Cited: 23Cited Reference Count: 61},
	month = {Apr},
	pages = {2666-2677},
	type = {Article},
	abstract = {Four mixed O,S binding ligand precursors derived from maltol (3-hydroxy-2-methyl-4-pyrone) have been chelated to gallium(III), indium(III), and lanthanide(III) ions to yield a series of metal complexes. The four ligand precursors include two pyranthiones, 3-hydroxy-2-methyl-4-pyranthione, commonly known as thiomaltol (Htma), and 2-ethyl-3-hydroxy-4-pyranthione, commonly known as ethylthiornaltol (Hetma), and two pyridinethiones, 3-hydroxy-2-methyl-4(H)-pyridinethione (Hmppt) and 3-hydroxy-1,2-dimethyl-4-pyridinethione (Hdppt). Dimeric forms of the pyridinethiones, Hmppt dimer and Hdppt dimer, were also isolated and characterized. Complete characterization of the monomeric organic compounds is reported including acidity constants and crystal structures of Htma, Hetma, and Hdppt dimer. Reacting the four monomeric ligand precursors with Ga3+ and In3+ ions yielded new tris(bidentate ligand) complexes. X-ray-quality crystals of the fac isomer of Ga(tma)(3) were also obtained. New complexes with a range of anthanicles (Ln(3+)) were also synthesized with the two pyranthiones, Htma and Hetma. The synthesis reactions yielded complexes of the type LnL(3)center dot xH(2)O and LnL(2)(OH)center dot xH(2)O, as indicated by elemental analysis and spectroscopic evidence such as mass spectral data and IR and NMR spectra.},
	keywords = {ACID, aluminum, CHELATE COMPLEXES, CHEMISTRY, CRYSTAL-STRUCTURE, DIAGNOSTIC-TOOLS, gallium, indium, METAL-COMPLEXES, RADIOPHARMACEUTICALS},
	isbn = {0020-1669},
	url = {<Go to ISI>://000228374400017},
	author = {Monga, V. and Patrick, B. O. and Orvig, Chris}
}
@article {1266,
	title = {Novel carbohydrate-appended metal complexes for potential use in molecular imaging},
	journal = {Chemistry-a European Journal},
	volume = {11},
	number = {1},
	year = {2005},
	note = {ISI Document Delivery No.: 887BZTimes Cited: 27Cited Reference Count: 60},
	month = {Dec},
	pages = {195-203},
	type = {Article},
	abstract = {Seven discrete sugar-pendant diamines were complexed to the {M(CO)(3)}(+) (Tc-99m/Re) core: 1,3-diamino-2-propyl beta-D-glucopyranoside (L-1), 1,3-diamino-2-propyl beta-D-xylopyranoside (L-2), 1,3-diamino-2-propyl alpha-D-mannopyranoside (L-3), 1,3-diamino-2-propyl alpha-D-galactopyranoside (L-4), 1,3diamino-2-propyl beta-D-galactopyranoside (L-5), 1,3-diamino-2-propyl beta-(alpha-D-glucopyranosyl-(1,4)-D-glucopyrano- side) (L-6), and bis(aminomethyl)bis[(beta-D-glucopyranosyloxy)methyl]methane (L-7). The Re complexes [Re((LL7)-L-1)(Br)(CO)(3)] were characterized by H-1 and C-13 1D/2D NMR spectroscopy which confirmed the pendant nature of the carbohydrate moieties in solution. Additional characterization was provided by IR spectroscopy, elemental analysis, and mass spectrometry. Two analogues, [Re(L-2)(CO)(3)Br] and [Re(L-3)(CO)(3)Br], were characterized in the solid state by X-ray crystallography and represent the first reported structures of Re organometallic carbohydrate compounds. Conductivity measurements in H2O established that the complexes exist as [Re(L-1-L-7)- (H2O)(CO)(3)]Br in aqueous conditions. Radiolabelling of V-L 7 with [Tc-99m(H2O)(3)(CO)(3)](+) afforded in high yield compounds of identical character to the Re analogues. The radiolabelled compounds were determined to exhibit high in vitro stability towards ligand exchange in the presence of an excess of either cysteine or histidine over a 24 h period.},
	keywords = {AMINO-SUGARS, ANTITUMOR-ACTIVITY, carbohydrates, CRYSTAL-STRUCTURES, D-GLUCOSE, HIGH-AFFINITY, IN-VITRO, molecular imaging, PALLADIUM(II) COMPLEXES, RADIOPHARMACEUTICALS, rhenium, STRUCTURAL-CHARACTERIZATION, SUGAR-PENDANT, TC-99M, technetium},
	isbn = {0947-6539},
	url = {<Go to ISI>://000226278700018},
	author = {Storr, T. and Obata, M. and Fisher, C. L. and Bayly, S. R. and Green, D. E. and Brudzinska, I. and Mikata, Y. and Patrick, B. O. and Adam,Michael J. and Yano, S. and Orvig, Chris}
}
@article {1266,
	title = {Novel carbohydrate-appended metal complexes for potential use in molecular imaging},
	journal = {Chemistry-a European Journal},
	volume = {11},
	number = {1},
	year = {2005},
	note = {ISI Document Delivery No.: 887BZTimes Cited: 27Cited Reference Count: 60},
	month = {Dec},
	pages = {195-203},
	type = {Article},
	abstract = {Seven discrete sugar-pendant diamines were complexed to the {M(CO)(3)}(+) (Tc-99m/Re) core: 1,3-diamino-2-propyl beta-D-glucopyranoside (L-1), 1,3-diamino-2-propyl beta-D-xylopyranoside (L-2), 1,3-diamino-2-propyl alpha-D-mannopyranoside (L-3), 1,3-diamino-2-propyl alpha-D-galactopyranoside (L-4), 1,3diamino-2-propyl beta-D-galactopyranoside (L-5), 1,3-diamino-2-propyl beta-(alpha-D-glucopyranosyl-(1,4)-D-glucopyrano- side) (L-6), and bis(aminomethyl)bis[(beta-D-glucopyranosyloxy)methyl]methane (L-7). The Re complexes [Re((LL7)-L-1)(Br)(CO)(3)] were characterized by H-1 and C-13 1D/2D NMR spectroscopy which confirmed the pendant nature of the carbohydrate moieties in solution. Additional characterization was provided by IR spectroscopy, elemental analysis, and mass spectrometry. Two analogues, [Re(L-2)(CO)(3)Br] and [Re(L-3)(CO)(3)Br], were characterized in the solid state by X-ray crystallography and represent the first reported structures of Re organometallic carbohydrate compounds. Conductivity measurements in H2O established that the complexes exist as [Re(L-1-L-7)- (H2O)(CO)(3)]Br in aqueous conditions. Radiolabelling of V-L 7 with [Tc-99m(H2O)(3)(CO)(3)](+) afforded in high yield compounds of identical character to the Re analogues. The radiolabelled compounds were determined to exhibit high in vitro stability towards ligand exchange in the presence of an excess of either cysteine or histidine over a 24 h period.},
	keywords = {AMINO-SUGARS, ANTITUMOR-ACTIVITY, carbohydrates, CRYSTAL-STRUCTURES, D-GLUCOSE, HIGH-AFFINITY, IN-VITRO, molecular imaging, PALLADIUM(II) COMPLEXES, RADIOPHARMACEUTICALS, rhenium, STRUCTURAL-CHARACTERIZATION, SUGAR-PENDANT, TC-99M, technetium},
	isbn = {0947-6539},
	url = {<Go to ISI>://000226278700018},
	author = {Storr, T. and Obata, M. and Fisher, C. L. and Bayly, S. R. and Green, D. E. and Brudzinska, I. and Mikata, Y. and Patrick, B. O. and Adam,Michael J. and Yano, S. and Orvig, Chris}
}
@article {805,
	title = {Carbohydrate conjugates for molecular imaging and radiotherapy: Tc-99m(I) and Re-186(I) tricarbonyl complexes of N-(2 {\textquoteright}-hydroxybenzyl)-2-amino-2-deoxy-D-glucose},
	journal = {Bioconjugate Chemistry},
	volume = {15},
	number = {4},
	year = {2004},
	note = {ISI Document Delivery No.: 840SWTimes Cited: 39Cited Reference Count: 17},
	month = {Jul-Aug},
	pages = {923-926},
	type = {Article},
	abstract = {An approach to a new class of potential radiopharmaceuticals is demonstrated by the labeling of a glucosamine derivative with the tricarbonyls of Tc-99m and Re-186. The proligand HL2 (N-(2{\textquoteright}-hydroxybenzyl)-2-amino-2-deoxy-d-glucose) was produced by hydrogenation of the corresponding Schiff base and reacted with [NEt4](2)[Re(CO)(3)Br-3] to form the neutral complex [(L-2)Re(CO)(3)] in 40\% yield. H-1 and C-13 NMR spectra indicate that the {Re(CO)(3)} core is bound in a tridentate fashion via the amino N, phenolato O, and C-3 hydroxyl O atoms of the ligand. At the tracer-level, labeling of HL2 with [Tc-99m(CO)(3)(H2O)(3)](+) and [Re-186(CO)(3)(H2O)(3)](+) was achieved in aqueous conditions in 95 +/- 2\% and 94 +/- 3\% average radiochemical yields, respectively.},
	keywords = {BIOMOLECULES, GLUCOSE, LIGAND SYSTEMS, RADIOPHARMACEUTICALS, SUGARS},
	isbn = {1043-1802},
	url = {<Go to ISI>://000222880900032},
	author = {Bayly, S. R. and Fisher, C. L. and Storr, T. and Adam,Michael J. and Orvig, Chris}
}
@article {805,
	title = {Carbohydrate conjugates for molecular imaging and radiotherapy: Tc-99m(I) and Re-186(I) tricarbonyl complexes of N-(2 {\textquoteright}-hydroxybenzyl)-2-amino-2-deoxy-D-glucose},
	journal = {Bioconjugate Chemistry},
	volume = {15},
	number = {4},
	year = {2004},
	note = {ISI Document Delivery No.: 840SWTimes Cited: 39Cited Reference Count: 17},
	month = {Jul-Aug},
	pages = {923-926},
	type = {Article},
	abstract = {An approach to a new class of potential radiopharmaceuticals is demonstrated by the labeling of a glucosamine derivative with the tricarbonyls of Tc-99m and Re-186. The proligand HL2 (N-(2{\textquoteright}-hydroxybenzyl)-2-amino-2-deoxy-d-glucose) was produced by hydrogenation of the corresponding Schiff base and reacted with [NEt4](2)[Re(CO)(3)Br-3] to form the neutral complex [(L-2)Re(CO)(3)] in 40\% yield. H-1 and C-13 NMR spectra indicate that the {Re(CO)(3)} core is bound in a tridentate fashion via the amino N, phenolato O, and C-3 hydroxyl O atoms of the ligand. At the tracer-level, labeling of HL2 with [Tc-99m(CO)(3)(H2O)(3)](+) and [Re-186(CO)(3)(H2O)(3)](+) was achieved in aqueous conditions in 95 +/- 2\% and 94 +/- 3\% average radiochemical yields, respectively.},
	keywords = {BIOMOLECULES, GLUCOSE, LIGAND SYSTEMS, RADIOPHARMACEUTICALS, SUGARS},
	isbn = {1043-1802},
	url = {<Go to ISI>://000222880900032},
	author = {Bayly, S. R. and Fisher, C. L. and Storr, T. and Adam,Michael J. and Orvig, Chris}
}
@article {758,
	title = {Boon and bane of metal ions in medicine},
	journal = {Science},
	volume = {300},
	number = {5621},
	year = {2003},
	note = {ISI Document Delivery No.: 675WDTimes Cited: 99Cited Reference Count: 30},
	month = {May},
	pages = {936-939},
	type = {Review},
	abstract = {In biological systems metal ions promote responses that range from deficiency to toxicity. Some, such as iron and zinc, have a known optimal intake range for normal, healthy individuals. Metal ions contained within well-designed molecules already constitute a great boon for the medicinal pharmacopoeia. However, whether essential or not, the threshold for toxicity can be very low. One of the challenges of designing metal-based drugs is to balance the potential toxicity of an active formulation with the substantial positive impact of these increasingly common therapeutic and diagnostic aids.},
	keywords = {AGENTS, COMPLEXES, RADIOPHARMACEUTICALS},
	isbn = {0036-8075},
	url = {<Go to ISI>://000182719800043},
	author = {Thompson, K. H. and Orvig, Chris}
}
@article {5232,
	title = {Chemistry of Re with N,N {\textquoteright}-bis(2-pyridylmethyl)ethylenediamine (H(2)pmen): Hydrolysis, dehydrogenation, and ternary complexes},
	journal = {Inorganic Chemistry},
	volume = {40},
	number = {9},
	year = {2001},
	note = {ISI Document Delivery No.: 423DBTimes Cited: 13Cited Reference Count: 49},
	month = {Apr},
	pages = {2005-2010},
	type = {Article},
	abstract = {A number of Re complexes with N,N {\textquoteright} -bis(2-pyridylmethyl)ethylenediamine (H(2)pmen) have been made from [NH4]-[ReO4]. . [ReOCl(2)H(2)pmen)]Cl, [ReOCl(Hpmen)][ReO4], and [ReO2(H(2)pmen)] [ReO4] are related by hydrolysis/HCl substitution [ReOCl(Hpmen)] [ReO4] was structurally characterized and found to contain a water-stable amido-Re bend. Dehydrogenation of the N-donor ligand from each amine to imine with concomitant two-electron reduction of the Re center occurs readily in these systems. With suitable 3-hydroxy-4-pyrones, ternary complexes such as [(ReCl)-Cl-III(ma)(C14H14N4)][ReO4]. CH3OH, 5, were made from [NH4][ReO4], H(2)pmen . 4HCl and pyrones in one-pot syntheses. 5, a seven-coordinate Re-III complex, was structurally characterized.},
	keywords = {aluminum, CHELATE COMPLEXES, COORDINATION-COMPOUNDS, gallium, LIGANDS, RADIOPHARMACEUTICALS, RAY CRYSTAL-STRUCTURE, Rhenium complexes, technetium, TRIS(2-PYRIDYLMETHYL)AMINE},
	isbn = {0020-1669},
	url = {<Go to ISI>://000168159200007},
	author = {Xu, L. and Pierreroy, J. and Patrick, B. O. and Orvig, Chris}
}
@article {5231,
	title = {[ReO(N2O2)X] complexes: "4+1"?},
	journal = {Inorganic Chemistry},
	volume = {40},
	number = {18},
	year = {2001},
	note = {ISI Document Delivery No.: 466JNTimes Cited: 3Cited Reference Count: 36},
	month = {Aug},
	pages = {4623-4626},
	type = {Article},
	abstract = {{[ReO(ppme)X] (where ppme(2-) is 2,5-diazo-N,N {\textquoteright} -dimethylhexyl-1,6-bis(phenylphosphinate)},
	keywords = {CHEMISTRY, OXO-COMPLEXES, PEPTIDES, RADIOPHARMACEUTICALS, RHENIUM(V), SCHIFF-BASE LIGANDS, STABILITY, TC-99M, TECHNETIUM COMPLEXES, X-ray structures},
	isbn = {0020-1669},
	url = {<Go to ISI>://000170642600019},
	author = {Xu, L. and Lowe, M. P. and Rettig, S. J. and Orvig, Chris}
}
@article {4983,
	title = {Seven-coordinate [(ReON4X2)-O-V](+) complexes (X = O and Cl)},
	journal = {Inorganic Chemistry},
	volume = {39},
	number = {26},
	year = {2000},
	note = {ISI Document Delivery No.: 385TFTimes Cited: 10Cited Reference Count: 29},
	month = {Dec},
	pages = {5958-5963},
	type = {Article},
	abstract = {The oxorhenium(V) complexes with ligands containing N-4 (H(2)pmen) and N4O2 (H(2)bbpen, H(2)Clbbpen, and H(2)bped) donor atom sets have been synthesized. X-ray crystallographic analyses of the [ReO(H(2)pmen)Cl-2](+), [ReO(bbpen)](+), and [ReO(bped)](+) complexes showed that all three cations share a rate seven-coordinate structure with a distorted pentagonal bipyramidal geometry, which represents a novel and potentially general structural motif in Re-V=O complexes. H-1 NMR spectroscopy shows that the structures of the complexes are retained in the solution.},
	keywords = {CHELATION, CHEMISTRY, LIGANDS, N3O2, pyridyl, RADIOPHARMACEUTICALS, rhenium, technetium, TRIS(2-PYRIDYLMETHYL)AMINE},
	isbn = {0020-1669},
	url = {<Go to ISI>://000166019200010},
	author = {Xu, L. and Setyawati, I. A. and Pierreroy, J. and Pink, M. and Young, V. G. and Patrick, B. O. and Rettig, S. J. and Orvig, Chris}
}
@article {4410,
	title = {Complexation of gallium(III) by 2-hydroxynicotinic acid and 3-hydroxypicolinic acid in aqueous solution},
	journal = {Inorganica Chimica Acta},
	volume = {273},
	number = {1-2},
	year = {1998},
	note = {ISI Document Delivery No.: ZP204Times Cited: 17Cited Reference Count: 27XXXIII International Conference on Coordination ChemistryAUG 30-SEP 04, 1998FLORENCE, ITALY},
	month = {May},
	pages = {47-53},
	type = {Proceedings Paper},
	abstract = {The deprotonations of 2-hydroxynicotinic acid (H(2)nic) and 3-hydroxypicolinic acid (H(2)pic) and the complexation of these molecules with Ga3+ were studied by H-1 NMR, UV-Vis spectrophotometry and potentiometric titration. Both ligands bind Ga3+ at very low pH; the ligand binds in the monodeprotonated form. The stability constants of the [Ga(HL)(n)]((3-n)+) (L = nic or pic; n = 1, 2, or 3) complexes were measured at 25 degrees C, 1.0 M NaCl (for beta(1)) and 0.16 M NaCl (for beta(2) and beta(3)); for H(2)nic (H(2)pic), log beta(1) = 6.78 (7.04), log beta(2) = 12.43 (13.09) and log beta(3) = 16.20 (17.74). At higher pH, polynuclear mixed ligand-hydroxo species form, although their composition and stability could not be determined. These complexes undergo hydrolysis to form [Ga(OH)(4)](-) above pH 7. (C) 1998 Elsevier Science S.A. All rights reserved.},
	keywords = {3-HYDROXY-4-PYRIDINONES, aluminum, CHELATION, CHEMISTRY, COMPLEXES, EQUILIBRIUM, GA-68, gallium complexes, hydroxynicotinic acid, hydroxypicolinic acid complexes, INDIUM COMPLEXES, INVIVO, LIGANDS, RADIOPHARMACEUTICALS},
	isbn = {0020-1693},
	url = {<Go to ISI>://000073728200008},
	author = {Stephens, A. K. W. and Orvig, Chris}
}
@article {3815,
	title = {Bis(ligand) rhenium(V) and technetium(V) complexes of two naturally occurring binding moieties (oxazoline and thiazoline)},
	journal = {Inorganic Chemistry},
	volume = {35},
	number = {2},
	year = {1996},
	note = {ISI Document Delivery No.: TR240Times Cited: 39Cited Reference Count: 19},
	month = {Jan},
	pages = {368-372},
	type = {Article},
	abstract = {{Attempts to prepare tris(ligand) metal complexes of technetium in intermediate oxidation states with potentially bidentate oxazoline- and thiazoline-containing ligands were unsuccessful; when pertechnetate was reduced in the presence of excess ligand, TcO2 . xH(2)O was produced. Instead, by reaction with preformed M . O cores, a series of oxotechnetium(V) and oxorhenium(V) complexes of the formula MOXL(2) (M = Re},
	keywords = {COORDINATION CHEMISTRY, RADIOPHARMACEUTICALS, RAY CRYSTAL-STRUCTURE, SIDEROPHORE, TC-99M},
	isbn = {0020-1669},
	url = {<Go to ISI>://A1996TR24000018},
	author = {Shuter, E. and Hoveyda, H. R. and Karunaratne, V. and Rettig, S. J. and Orvig, Chris}
}
@article {3021,
	title = {CHARACTERIZATION OF TRIS(N-SUBSTITUTED-2-METHYL-3-HYDROXY-4-PYRIDINONATO)TECHNETIUM(IV) CATIONS},
	journal = {Inorganic Chemistry},
	volume = {33},
	number = {24},
	year = {1994},
	note = {ISI Document Delivery No.: PU080Times Cited: 14Cited Reference Count: 20},
	month = {Nov},
	pages = {5607-5609},
	type = {Note},
	keywords = {3-HYDROXY-4-PYRIDINONES, AGENTS, aluminum, CHEMISTRY, COMPLEXES, gallium, INVIVO, RADIOPHARMACEUTICALS, TC-99M, technetium},
	isbn = {0020-1669},
	url = {<Go to ISI>://A1994PU08000042},
	author = {Edwards, D. S. and Liu, S. and Poirier, M. J. and Zhang, Z. H. and Webb, G. A. and Orvig, Chris}
}
@article {2868,
	title = {RHENIUM(V) AND TECHNETIUM(V) COMPLEXES OF BIDENTATE (0, 0) MONOBASIC 3-OXY-4-PYRONATO AND -4-PYRIDINONATO LIGANDS - X-RAY STRUCTURES OF CIS-BROMOBIS(3-METHYL-2-OXY-4-PYRONATO)OXORHENIUM(V), TETRA-N-BUTYLAMMONIUM TRIBROMO(3-METHYL-2-OXY-4-PYRONATO)OXORHENA},
	journal = {Inorganic Chemistry},
	volume = {32},
	number = {21},
	year = {1993},
	note = {ISI Document Delivery No.: MC686Times Cited: 27Cited Reference Count: 39},
	month = {Oct},
	pages = {4491-4497},
	type = {Article},
	abstract = {{A series of technetium(V) and rhenium(V) complexes of the form [MOXL2], where L is a bidentate (0, 0) monobasic ligand, 2-methyl-3-oxy-4-pyronate (maltolate, ma-) or 1,2-dimethyl-3-oxy-4-pyridinonate (dpp-), and X is a halo ligand},
	keywords = {3-HYDROXY-4-PYRIDINONES, aluminum, CHEMISTRY, CRYSTAL-STRUCTURE, MALTOL, MATRIX, NUCLEAR-MEDICINE, RADIOPHARMACEUTICALS, REACTIVITY, SCHIFF-BASES},
	isbn = {0020-1669},
	url = {<Go to ISI>://A1993MC68600005},
	author = {Luo, H. Y. and Rettig, S. J. and Orvig, Chris}
}
