@article {338,
	title = {De Novo terpenoid biosynthesis by the dendronotid nudibranch Melibe leonina},
	journal = {Chemoecology},
	volume = {12},
	number = {4},
	year = {2002},
	note = {ISI Document Delivery No.: 635GATimes Cited: 6Cited Reference Count: 23},
	pages = {199-202},
	type = {Article},
	abstract = {Stable isotope feeding studies using [1,2-C-13(2)]-sodium acetate have demonstrated that 2,6-dimetbyl-5-heptenal (1), a putative defensive allomone, is made by the Dendronotid nudibranch Melibe leonina via de novo biosynthesis.},
	keywords = {biosynthesis, CADLINA-LUTEOMARGINATA, chemical, CHEMICAL DEFENSE, defense nudibranch, DORID-NUDIBRANCHS, ECOLOGY, ISOTOPE INCORPORATION EVIDENCE, OPISTHOBRANCH MOLLUSK, ORIGIN, terpenoid, TRIOPHAMINE},
	isbn = {0937-7409},
	url = {<Go to ISI>://000180389600006},
	author = {Barsby, T. and Linington, R. G. and Andersen, R. J.}
}
@article {4857,
	title = {Geographic variation and tissue distribution of endogenous terpenoids in the Northeastern Pacific Ocean dorid nudibranch Cadlina luteomarginata: Implications for the regulation of de novo biosynthesis},
	journal = {Journal of Chemical Ecology},
	volume = {26},
	number = {2},
	year = {2000},
	note = {ISI Document Delivery No.: 285PTTimes Cited: 6Cited Reference Count: 14},
	month = {Feb},
	pages = {377-389},
	type = {Article},
	abstract = {Gas chromatography (GC) analyses of whole animal skin extracts and individual tissue extracts obtained from specimens of Cadlina luteo-marginata collected in British Columbia and southern California were used to determine if concentrations of the nudibranch{\textquoteright}s biosynthetic products-albicanyl acetate (1), cadlinaldehyde (2), and luteone (3)-vary significantly between two populations, among individuals of a population, and among body tissues of individual specimens. The major biosynthetic product, albicanyl acetate (1), has the same concentration in both British Columbia and California populations, while the British Columbia population contains greater total amounts of 2 and 3 than the California population. Within individuals from one population, the largest proportion of endogenous metabolites is in the dorsum, specifically in the mantle dermal formations and margins. The GC analyses show that across geographically separated populations and within geographically localized populations the concentration of endogenous metabolites is inversely correlated with availability of structurally similar compounds from dietary sources. This suggests that the de novo biosynthesis of defensive compounds might be regulated according to need.},
	keywords = {Cadlina luteomarginata, CHEMICAL DEFENSE, de novo biosynthesis, instraspecific variation, MOLLUSKS, nudibranch, opistobranch, terpenes},
	isbn = {0098-0331},
	url = {<Go to ISI>://000085398000005},
	author = {Kubanek, J. and Faulkner, D. J. and Andersen, R. J.}
}
@article {4034,
	title = {Investigations of terpenoid biosynthesis by the dorid nudibranch Cadlina luteomarginata},
	journal = {Journal of Organic Chemistry},
	volume = {62},
	number = {21},
	year = {1997},
	note = {ISI Document Delivery No.: YC657Times Cited: 16Cited Reference Count: 21},
	month = {Oct},
	pages = {7239-7246},
	type = {Article},
	abstract = {Stable isotope incorporation studies with [1,2-C-13(2)]acetate, [1,2-C-13(2),O-18(1)]acetate, [1,2-C-13],mevalonolactone, and [2-C-13]mevalonolactone have been used to investigate the biosynthesis of the terpenoids albicanyl acetate (1), cadlinaldehyde (2), and luteone (3) by the dorid nudibranch Cadlina luteomarginata. The results have shown that all three terpenoids are synthesized de novo by C, luteomarginata and the incorporation patterns are consistent with the biogenetic proposal that the new cadlinalane and luteane carbon skeletons are formed by degradation of a sesterterpenoid precursor. This represents the first demonstration of sesterterpenoid biosynthesis by a marine mollusc. Quantitative analysis has shown that only a small turnover of metabolites takes place during the feeding experiments but that the newly formed molecules have extremely high levels of incorporation of labeled precursors.},
	keywords = {CARBON SKELETON, CHEMICAL DEFENSE, MARINE NATURAL-PRODUCTS, SPONGE APLYSILLA-GLACIALIS},
	isbn = {0022-3263},
	url = {<Go to ISI>://A1997YC65700039},
	author = {Kubanek, J. and Graziani, E. I. and Andersen, R. J.}
}
@article {3946,
	title = {New terpenoid metabolites from the skin extracts, an egg mass, and dietary sponges of the Northeastern Pacific dorid nudibranch Cadlina luteomarginata},
	journal = {Canadian Journal of Chemistry-Revue Canadienne De Chimie},
	volume = {75},
	number = {6},
	year = {1997},
	note = {ISI Document Delivery No.: XL704Times Cited: 27Cited Reference Count: 26},
	month = {Jun},
	pages = {773-789},
	type = {Article},
	abstract = {Chemical investigations of Cadlina luteomarginata skin extracts, egg masses, and dietary sponges have led to the identification of the novel terpenoids cadlinaldehyde (30), spongian 32, seco-spongian 35, 20-acetoxy-12-marginatone (38), and lutenolide (39) from the nudibranch skin extracts, the new drimane sesquiterpenoid 1 alpha,2 alpha-diacetoxyalbicanyl acetate (40) from the nudibranch{\textquoteright}s egg mass, and the new sesquiterpenoids O-methyl-9-oxofurodysininlactone (47), 2-oxomicrocionin-2-lactone (48), and O-methyl-2-oxomicrocionin-2-lactone (49), from the dietary sponge Pleraplysilla sp. The known terpenoids furodysinin (1), furodysin (16), marginatafuran (21), and 9,11-dihydrogracillin A (37), which have been frequently isolated from C. luteomarginata skin extracts, were found for the first time in extracts of the dietary sponges Pleraplysilla sp. and Aplysilla sp. One of the new terpenoids, cadlinaldehyde (30), has an unprecedented degraded sesterterpenoid skeleton.},
	keywords = {APLYSILLA-GLACIALIS, CHEMICAL DEFENSE, MOLLUSKS, nudibranch, SPONGE, structure elucidation, terpenoids},
	isbn = {0008-4042},
	url = {<Go to ISI>://A1997XL70400025},
	author = {Dumdei, E. J. and Kubanek, J. and Coleman, J. E. and Pika, J. and Andersen, R. J. and Steiner, J. R. and Clardy, J.}
}
@article {3818,
	title = {Feeding avoidance of balsam poplar by snowshoe hares is related to abundance of buds},
	journal = {Ecoscience},
	volume = {3},
	number = {2},
	year = {1996},
	note = {ISI Document Delivery No.: UP163Times Cited: 0Cited Reference Count: 12},
	pages = {223-225},
	type = {Article},
	abstract = {In boreal forests of North America balsam poplar (Populus balsamifera) stems contain several chemicals distasteful to snowshoe hares. Some chemicals occur in internodes, others in buds. We examined whether an antifeedant chemical in buds (2,4,6-trihydroxydihydrochalcone) also inhibited hares from feeding on internodes. This chemical was painted onto buds of palatable willow (Salix lucida) twigs which were presented to harts in cafeteria trials. Hares avoided twigs with painted buds and the degree of aversion was related to the abundance of painted buds. Although the number of buds per unit mass of balsam poplar stems declined from one to five years old, the remaining buds were sufficient to induce a feeding deterrence.},
	keywords = {ANTIFEEDANT, antifeedant chemicals, balsam poplar, CHEMICAL DEFENSE, GREEN ALDER, PINOSYLVIN METHYL-ETHER, snowshoe hare},
	isbn = {1195-6860},
	url = {<Go to ISI>://A1996UP16300013},
	author = {Sinclair, A. R. E. and Williams, D. E. and Andersen, R. J. and Pain, J.}
}
