@article {749,
	title = {Briarane, erythrane, and aquariane diterpenoids from the Caribbean gorgonian Erythropodium caribaeorum},
	journal = {European Journal of Organic Chemistry},
	number = {18},
	year = {2003},
	note = {ISI Document Delivery No.: 726HFTimes Cited: 5Cited Reference Count: 15},
	month = {Sep},
	pages = {3515-3523},
	type = {Article},
	abstract = {Seven new diterpenoids belonging to the briarane [erythrolides R (5), S (6), T (7), and U (8)], erythrane [erythrolide V (9)], and aquariane [aquariolides B (10) and C (11)] skeletal classes have been isolated from the encrusting gorgonian Erythropodium caribaeorum. The structures of the new compounds were elucidated by spectroscopic analysis and chemical interconversions. A biogenetic proposal that links carbon skeletons found in E. caribaeorum diterpenoids is presented. (C) Wiley-VCH Verlag GmbH Co.},
	keywords = {asymmetric, bioorganic chemistry, ELEUTHEROBIN, ERYTHROLIDES, natural products, structure elucidation, SYNTHESIS, terpenoids},
	isbn = {1434-193X},
	url = {<Go to ISI>://000185592300005},
	author = {Taglialatela-Scafati, O. and Craig, K. S. and Reberioux, D. and Roberge, M. and Andersen, R. J.}
}
@article {701,
	title = {Synthesis and antimitotic/cytotoxic activity of hemiasterlin analogues},
	journal = {Journal of Natural Products},
	volume = {66},
	number = {2},
	year = {2003},
	note = {ISI Document Delivery No.: 652JHTimes Cited: 45Cited Reference Count: 37},
	month = {Feb},
	pages = {183-199},
	type = {Article},
	abstract = {The antimitotic sponge tripeptide hemiasterlin (1) and a number of structural analogues have been synthesized and evaluated in cell-based assays for both cytotoxic and antimitotic activity in order to explore the SAR for this promising anticancer drug lead. One synthetic analogue, SPA110 (8), showed more potent in vitro cytotoxicty and antimitotic activity than the natural product hemiasterlin (1), and consequently it has been subjected to thorough preclinical evaluation and targeted for clinical evaluation. The details of the synthesis of hemiasterlin (1) and the analogues and a discussion of how their biological activities vary with their structures are presented in this paper.},
	keywords = {(-)-HEMIASTERLIN, AGENTS, ALPHA-AMINO-ACIDS, ASYMMETRIC-SYNTHESIS, AZIDATION, CYTOTOXIC PEPTIDES, ELEUTHEROBIN, TRIPEPTIDE, TUBULIN},
	isbn = {0163-3864},
	url = {<Go to ISI>://000181375700005},
	author = {Nieman, J. A. and Coleman, J. E. and Wallace, D. J. and Piers, E. and Lim, L. Y. and Roberge, M. and Andersen, R. J.}
}
@article {516,
	title = {Diterpenoids from cultured Erythropodium caribaeorum},
	journal = {Organic Letters},
	volume = {4},
	number = {23},
	year = {2002},
	note = {ISI Document Delivery No.: 614DUTimes Cited: 16Cited Reference Count: 19},
	month = {Nov},
	pages = {4085-4088},
	type = {Article},
	abstract = {[GRAPHICS] The known antimitotic agent eleutherobin and the briarane diterpenoids erythrolides A and B have been isolated from cultured specimens of Erythropodium caribaeorum in amounts,comparable to those reported from wild-harvested reef animals. The novel diterpenoid aquariolide A, having an unprecedented highly-rearranged carbon skeleton (named aquariane), has also been found. The aquariane skeleton can be formally derived from the briarane-skeleton by sequential di-pi-methane and vinyl-cyclopropane rearrangements.},
	keywords = {ELEUTHEROBIN, ERYTHROLIDES, HALICHONDRIN-B, PHARMACOPHORE, REARRANGEMENT},
	isbn = {1523-7060},
	url = {<Go to ISI>://000179173700025},
	author = {Taglialatela-Scafati, O. and Deo-Jangra, U. and Campbell, M. and Roberge, M. and Andersen, R. J.}
}
@article {5025,
	title = {Antimitotic diterpenoids from Erythropodium caribaeorum: isolation artifacts and putative biosynthetic intermediates},
	journal = {Tetrahedron Letters},
	volume = {42},
	number = {16},
	year = {2001},
	note = {ISI Document Delivery No.: 421EJTimes Cited: 18Cited Reference Count: 6},
	month = {Apr},
	pages = {2953-2956},
	type = {Article},
	abstract = {Two new natural products, caribaeorane (12) and 15-hydroxycaribaeorane (11), have been identified in Erythropodium caribaeorum extracts by isolation of their C-4 methylketals 10 and 9. It has been demonstrated that eleutherobin (1) is an isolation artifact. A proposal for the late stages of the biosynthetic pathway to the E. calibaeorum antimitotic diterpenoids is presented. (C) 2001 Published by Elsevier Science Ltd.},
	keywords = {ELEUTHEROBIN, PACLITAXEL, SARCODICTYIN-A},
	isbn = {0040-4039},
	url = {<Go to ISI>://000168048900007},
	author = {Britton, R. and Roberge, M. and Berisch, H. and Andersen, R. J.}
}
@article {4775,
	title = {Antimitotic diterpenes from Erythropodium caribaeorum test pharmacophore models for microtubule stabilization},
	journal = {Organic Letters},
	volume = {2},
	number = {3},
	year = {2000},
	note = {ISI Document Delivery No.: 282UXTimes Cited: 36Cited Reference Count: 17},
	month = {Feb},
	pages = {257-260},
	type = {Article},
	abstract = {[GRAPHICS] Six new antimitotic diterpenes, 2-7, have been isolated from the Caribbean octocoral Erythropodium caribaeorum, Structural variations encountered in this group of natural products test recently proposed pharmacophore models for microtubule stabilizing compounds.},
	keywords = {AGENTS, ELEUTHEROBIN, TAXOL, TUBULIN},
	isbn = {1523-7060},
	url = {<Go to ISI>://000085238900007},
	author = {Cinel, B. and Roberge, M. and Behrisch, H. and van Ofwegen, L. P. and Castro, C. B. and Andersen, R. J.}
}
