@article {2209, title = {Phosphorus-containing block copolymer templates can control the size and shape of gold nanostructures}, journal = {Journal of the American Chemical Society}, volume = {130}, number = {39}, year = {2008}, note = {ISI Document Delivery No.: 353GITimes Cited: 17Cited Reference Count: 31Noonan, Kevin J. T. Gillon, Bronwyn H. Cappello, Vittorio Gates, Derek P.}, month = {Oct}, pages = {12876-+}, type = {Article}, abstract = {{Amphiphilic block copolymers containing phosphine moieties in the main chain are employed as macromolecular ligands for gold (1). The sequential living anionic copolymerization of isoprene (1) and the phosphaalkene}, keywords = {ARCHITECTURE, CROSS-LINKING, DIBLOCK COPOLYMER, HOMOPOLYMERS, LIVING ANIONIC-POLYMERIZATION, micelles, MORPHOLOGIES, multiple, NANOPARTICLES, nanotechnology, POLYMERS}, isbn = {0002-7863}, url = {://000259553700020}, author = {Noonan, K. J. T. and Gillon, B. H. and Cappello, V. and Gates, D. P.} } @article {399, title = {Studies of a benzoporphyrin derivative with Pluronics}, journal = {Canadian Journal of Chemistry-Revue Canadienne De Chimie}, volume = {80}, number = {10}, year = {2002}, note = {ISI Document Delivery No.: 623LCTimes Cited: 14Cited Reference Count: 22}, month = {Oct}, pages = {1321-1326}, type = {Article}, abstract = {The synthetic route for the benzoporphyrin derivatives produces two regioisomers in equimolar quantities (ring A and B isomers). A derivative of the A-ring product, BPD-MA (benzoporphyrin-derivative monoacid ring A, verteporfin), has recently been approved in North America and Europe for the treatment of age-related macular degeneration. The B-ring isomers, contrary to the A-ring isomers, exhibit high aggregation in many formulations, which results in inadequate drug delivery for clinical uses. To avoid aggregation, a non-ionic surfactant polymer such as a Pluronic - poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) - may be used as a formulation excipient. The triblock polymer investigated here is designated P123 (or poloxamer 403). When used to formulate a monoacid benzoporphyrin B-ring derivative (2), a critical micelle concentration of P123 in water occurred at approximately 0.015 to 0.03\%. The apparent pK(a) of compound 2 was dependent on its concentration in P123, and decreased as the molar ratio (P123:2) increased. High concentrations of P123 and neutral pH were found to be the best conditions to maintain the drug in its monomeric form. Kinetic studies suggest that the aggregate of 2 contains several molecules, and is formed by a catalyzed self-assembly process. Samples with 1 mg mL(-1) of drug, at pH = 7.4, and 4.8\% of Pluronic showed satisfactory capacity to load and keep monomers stable. This formulation has potential PDT applications.}, keywords = {AGGREGATION, AQUEOUS-SOLUTIONS, block copolymers, BPD, COPOLYMERS, DYNAMICS, formulation, micelles, PHOTODYNAMIC THERAPY, photodynamic therapy (PDT), PHOTOSENSITIZERS, photosensitizing drug, Pluronic, poloxamers, porphyrins, SURFACTANTS, THERMODYNAMICS}, isbn = {0008-4042}, url = {://000179703700007}, author = {Hioka, N. and Chowdhary, R. K. and Chansarkar, N. and Delmarre, D. and Sternberg, E. and Dolphin, D.} } @article {4732, title = {Colloid-catalysed arene hydrogenation in aqueous/supercritical fluid biphasic media}, journal = {Chemical Communications}, number = {11}, year = {2000}, note = {ISI Document Delivery No.: 316JJTimes Cited: 59Cited Reference Count: 24}, pages = {941-942}, type = {Article}, abstract = {Hydrogenation of arenes, including the lignin model compound 2-methoxy-4-propylphenol, has been effected using a Rh colloid in biphasic aqueous/supercritical ethane reaction media; this is the first successful example of an unsupported colloid-catalysed hydrogenation of a substrate in a supercritical fluid; the same reaction does not proceed in aqueous/supercritical carbon dioxide or ionic liquid/supercritical fluid media.}, keywords = {CO2, micelles, MILD, model compounds, PRESSURES, rhodium, SOLUBLE METAL-COMPLEXES, SPECTROSCOPY, SUPERCRITICAL CARBON-DIOXIDE, SYSTEMS}, isbn = {1359-7345}, url = {://000087163600026}, author = {Bonilla, R. J. and James, Brian R. and Jessop, P. G.} }