@article {829,
	title = {Investigations of alpha-siloxy-epoxide ring expansions forming 1-azaspirocyclic ketones},
	journal = {Journal of Organic Chemistry},
	volume = {69},
	number = {17},
	year = {2004},
	note = {ISI Document Delivery No.: 845XHTimes Cited: 13Cited Reference Count: 97},
	month = {Aug},
	pages = {5676-5683},
	type = {Article},
	abstract = {The construction of 1-azaspirocyclic cycloalkanones using a siloxy-epoxide semipinacol ring expansion process was examined. Functionalized 1-azaspiro[5.5]undecan-7-ones (1-azaspirocyclic cyclohexanones) proceeded in high chemical yields with complete diastereoselectivity using titanium tetrachloride as the Lewis acid promoter. The formation of functionalized 6-azaspiro[5.4]-decan-1-ones (1-azaspirocyclic cyclopentanones) proceeded in high chemical yield with little diastereoselectivity. Modification of reaction parameters such as the Lewis acid promoter or the nature of the silyl ether allowed for the preferential formation of either ("anti" or "syn" 1,2 alkyl shift) diastereomeric product. An explanation for the different reactivity profiles between the cyclobutanol silyl ethers and cyclopentanol silyl ethers is provided.},
	keywords = {1ST TOTAL-SYNTHESIS, ALDOL ALDOL PROCESS, ASYMMETRIC-SYNTHESIS, BAEYER-VILLIGER OXIDATION, LEWIS-ACIDS, ORGANIC-SYNTHESIS, PRACTICAL, QUATERNARY CARBON CENTERS, REARRANGEMENT, SEMI-PINACOL, SILYL ETHER REARRANGEMENTS, STEREOSELECTIVE CONSTRUCTION},
	isbn = {0022-3263},
	url = {<Go to ISI>://000223278200021},
	author = {Dake, G. R. and Fenster, M. D. B. and Fleury, M. and Patrick, B. O.}
}
@article {612,
	title = {A formal construction of fasicularin},
	journal = {Organic Letters},
	volume = {5},
	number = {23},
	year = {2003},
	note = {ISI Document Delivery No.: 741QDTimes Cited: 23Cited Reference Count: 42},
	month = {Nov},
	pages = {4313-4316},
	type = {Article},
	abstract = {Our synthetic approach toward fasicularin is presented. Key steps in this construction are a siloxy-epoxide semipinacol rearrangement, a B-alkyl Suzuki reaction and an intramolecular S(N)2 reaction.},
	keywords = {(+/-)-LEPADIFORMINE, CROSS-COUPLING, CYLINDRICINE, DIELS-ALDER REACTION, DIPOLAR CYCLOADDITION, ENANTIOMER, KETONES, MARINE ALKALOID LEPADIFORMINE, NATURAL, reaction, REARRANGEMENT, STEREOSELECTIVE CONSTRUCTION},
	isbn = {1523-7060},
	url = {<Go to ISI>://000186468000019},
	author = {Fenster, M. D. B. and Dake, G. R.}
}
