@article {2389,
	title = {Cytotoxicity of the traditional chinese medicine (TCM) plumbagin in its copper chemistry},
	journal = {Dalton Transactions},
	number = {48},
	year = {2009},
	note = {ISI Document Delivery No.: 527IETimes Cited: 3Cited Reference Count: 96Chen, Zhen-Feng Tan, Ming-Xiong Liu, Li-Min Liu, Yan-Cheng Wang, Heng-Shan Yang, Bin Peng, Yan Liu, Hua-Gang Liang, Hong Orvig, Chris},
	pages = {10824-10833},
	type = {Article},
	abstract = {The anticancer traditional Chinese medicine (TCM), plumbagin (PLN), was isolated from Plumbago Zeylanica. Reaction of plumbagin with Cu-II salt, afforded [Cu(PLN)(2)]center dot 2H(2)O (1). With 2,2{\textquoteright}-bipyridine (bipy) as a co-ligand, PLN reacts with Cu-II to give [Cu(PLN)(bipy)(H2O)](2)(NO3)(2)center dot 4H(2)O (2). 1 and 2 were characterized by elemental analysis, IR, ESI-MS spectra. Their crystal structures were determined by single crystal X-ray diffraction methods. The in vitro cytotoxicity of PLN, 1 and 2 against seven human tumour cell lines was assayed. The metal-based compounds exhibit enhanced cytotoxicity vs. that of free PLN, suggesting that these compounds display synergy in the combination of metal ions with PLN. The binding properties of PLN, 1 and 2 to DNA were investigated through UV-vis, fluorescence, CD spectra, and gel mobility shift assay, which indicated that 1 and 2 were non-covalent binding and mainly intercalated the neighboring base pairs of DNA. PLN, 1 and 2 exhibit inhibition activity to topoisomerase I (TOPO I), but 1 and 2 were more effective than PLN.},
	keywords = {BIOLOGICAL-ACTIVITY, CALF-THYMUS DNA, CANCER-CELLS, CRYSTAL-STRUCTURE, DNA CLEAVAGE ACTIVITY, IRON(II) COMPLEXES, METAL-COMPLEXES, N-PROPYL-NORFLOXACIN, PLATINUM ANTICANCER AGENTS, TOPOISOMERASE-I},
	isbn = {1477-9226},
	url = {<Go to ISI>://000272359900024},
	author = {Chen, Z. F. and Tan, M. X. and Liu, L. M. and Liu, Y. C. and Wang, H. S. and Yang, B. and Peng, Y. and Liu, H. G. and Liang, H. and Orvig, Chris}
}
@article {2370,
	title = {Glucosamine conjugates bearing N,N,O-donors: potential imaging agents utilizing the [M(CO)(3)](+) core (M = Re, Tc)},
	journal = {Dalton Transactions},
	number = {42},
	year = {2009},
	note = {ISI Document Delivery No.: 508YBTimes Cited: 2Cited Reference Count: 32Bowen, Meryn L. Lim, Nathaniel C. Ewart, Charles B. Misri, Ripen Ferreira, Cara L. Haefeli, Urs Adam, Michael J. Orvig, Chris},
	pages = {9216-9227},
	type = {Article},
	abstract = {The design rationale, synthesis and radiolabeling evaluation of four glucosamine conjugated ligands for the [Tc-99m(CO)(3)](+) core is described. The capability to bind the tricarbonyl core is initially demonstrated using the cold surrogate [Re(CO)(3)](+). The four compounds are competent chelates in binding [Tc-99m(CO)(3)](+) as labeling studies show, with yields ranging from 79 to 96\% and the resulting complexes showing stability in the presence of competing chelates for 24 h at 37 degrees C. The rhenium complexes were tested for hexokinase-catalysed phosphorylation, and the technetium complexes were tested for GLUT-1 mediated cell uptake - they showed a small amount of uptake but it was not glucose dependent, suggesting that it was not via the GLUT-1 transporters.},
	keywords = {BIOMOLECULES, EXPRESSION, GLUT-1, HEXOKINASE, IN-VITRO, METAL-COMPLEXES, TC-99M, technetium, TRANSPORTERS, TRICARBONYL COMPLEXES},
	isbn = {1477-9226},
	url = {<Go to ISI>://000270973800020},
	author = {Bowen, M. L. and Lim, N. C. and Ewart, C. B. and Misri, R. and Ferreira, C. L. and Hafeli, U. and Adam,Michael J. and Orvig, Chris}
}
@article {2370,
	title = {Glucosamine conjugates bearing N,N,O-donors: potential imaging agents utilizing the [M(CO)(3)](+) core (M = Re, Tc)},
	journal = {Dalton Transactions},
	number = {42},
	year = {2009},
	note = {ISI Document Delivery No.: 508YBTimes Cited: 2Cited Reference Count: 32Bowen, Meryn L. Lim, Nathaniel C. Ewart, Charles B. Misri, Ripen Ferreira, Cara L. Haefeli, Urs Adam, Michael J. Orvig, Chris},
	pages = {9216-9227},
	type = {Article},
	abstract = {The design rationale, synthesis and radiolabeling evaluation of four glucosamine conjugated ligands for the [Tc-99m(CO)(3)](+) core is described. The capability to bind the tricarbonyl core is initially demonstrated using the cold surrogate [Re(CO)(3)](+). The four compounds are competent chelates in binding [Tc-99m(CO)(3)](+) as labeling studies show, with yields ranging from 79 to 96\% and the resulting complexes showing stability in the presence of competing chelates for 24 h at 37 degrees C. The rhenium complexes were tested for hexokinase-catalysed phosphorylation, and the technetium complexes were tested for GLUT-1 mediated cell uptake - they showed a small amount of uptake but it was not glucose dependent, suggesting that it was not via the GLUT-1 transporters.},
	keywords = {BIOMOLECULES, EXPRESSION, GLUT-1, HEXOKINASE, IN-VITRO, METAL-COMPLEXES, TC-99M, technetium, TRANSPORTERS, TRICARBONYL COMPLEXES},
	isbn = {1477-9226},
	url = {<Go to ISI>://000270973800020},
	author = {Bowen, M. L. and Lim, N. C. and Ewart, C. B. and Misri, R. and Ferreira, C. L. and Hafeli, U. and Adam,Michael J. and Orvig, Chris}
}
@article {2369,
	title = {Long-chain rhenium and technetium glucosamine conjugates},
	journal = {Dalton Transactions},
	number = {42},
	year = {2009},
	note = {ISI Document Delivery No.: 508YBTimes Cited: 0Cited Reference Count: 44Bowen, Meryn L. Chen, Zhen-Feng Roos, Adrienne M. Misri, Ripen Haefeli, Urs Adam, Michael J. Orvig, Chris},
	pages = {9228-9236},
	type = {Article},
	abstract = {A series of five glucosamine-conjugated organometallic complexes of the tricarbonyl cores of technetium-99m and rhenium were made. Glucosamine was derivatized at the C-2 nitrogen with long chain alkyl spacers linked to either pyridyl-tert-nitrogen-phenol tridentate chelates or cyclopentadienyl ligating groups. The metal complexes of the tridentate ligands were formed by refluxing with [Re(CO)(3)(H2O)(3)]Br, or with a base and [Tc-99m(CO)(3)(H2O)(3)](+). These ligands were found to be competent chelates in binding the [Tc-99m(CO)(3)](+) core as radiolabeling yields ranged from 87 to 93\% and the resulting complexes are stable to cysteine and histidine challenges for 24 h. The cyclopentadienyl analogues were formed using a double ligand transfer reaction for the rhenium complexes and a single ligand transfer for the technetium-99m complexes. All five rhenium complexes were tested as substrates of hexokinase; two of these complexes were tested as hexokinase inhibitors and they were found to be competent inhibitors, suggesting that they may be able to interact with hexokinase. MTT cytotoxicity studies were performed and the complexes tested were found to be non-toxic to the concentrations tested (100 mu M or 1 mM). GLUT-1 mediated cell uptake studies were performed on all five technetium-99m complexes, and their cell entry was found to parallel their lipophilicities, suggesting that cellular uptake is by passive diffusion and is not mediated by GLUT-1.},
	keywords = {99M-TECHNETIUM, BIOMOLECULES, BREAST-CANCER, DERIVATIVES, HEXOKINASE, IN-VITRO, METAL-COMPLEXES, RE, TC-99M, TRANSPORT},
	isbn = {1477-9226},
	url = {<Go to ISI>://000270973800021},
	author = {Bowen, M. L. and Chen, Z. F. and Roos, A. M. and Misri, R. and Hafeli, U. and Adam,Michael J. and Orvig, Chris}
}
@article {2369,
	title = {Long-chain rhenium and technetium glucosamine conjugates},
	journal = {Dalton Transactions},
	number = {42},
	year = {2009},
	note = {ISI Document Delivery No.: 508YBTimes Cited: 0Cited Reference Count: 44Bowen, Meryn L. Chen, Zhen-Feng Roos, Adrienne M. Misri, Ripen Haefeli, Urs Adam, Michael J. Orvig, Chris},
	pages = {9228-9236},
	type = {Article},
	abstract = {A series of five glucosamine-conjugated organometallic complexes of the tricarbonyl cores of technetium-99m and rhenium were made. Glucosamine was derivatized at the C-2 nitrogen with long chain alkyl spacers linked to either pyridyl-tert-nitrogen-phenol tridentate chelates or cyclopentadienyl ligating groups. The metal complexes of the tridentate ligands were formed by refluxing with [Re(CO)(3)(H2O)(3)]Br, or with a base and [Tc-99m(CO)(3)(H2O)(3)](+). These ligands were found to be competent chelates in binding the [Tc-99m(CO)(3)](+) core as radiolabeling yields ranged from 87 to 93\% and the resulting complexes are stable to cysteine and histidine challenges for 24 h. The cyclopentadienyl analogues were formed using a double ligand transfer reaction for the rhenium complexes and a single ligand transfer for the technetium-99m complexes. All five rhenium complexes were tested as substrates of hexokinase; two of these complexes were tested as hexokinase inhibitors and they were found to be competent inhibitors, suggesting that they may be able to interact with hexokinase. MTT cytotoxicity studies were performed and the complexes tested were found to be non-toxic to the concentrations tested (100 mu M or 1 mM). GLUT-1 mediated cell uptake studies were performed on all five technetium-99m complexes, and their cell entry was found to parallel their lipophilicities, suggesting that cellular uptake is by passive diffusion and is not mediated by GLUT-1.},
	keywords = {99M-TECHNETIUM, BIOMOLECULES, BREAST-CANCER, DERIVATIVES, HEXOKINASE, IN-VITRO, METAL-COMPLEXES, RE, TC-99M, TRANSPORT},
	isbn = {1477-9226},
	url = {<Go to ISI>://000270973800021},
	author = {Bowen, M. L. and Chen, Z. F. and Roos, A. M. and Misri, R. and Hafeli, U. and Adam,Michael J. and Orvig, Chris}
}
@article {2528,
	title = {Synthesis and Characterization of a New Thiophene-Bridged Diamidophosphine [NPN] Donor Set and Its Coordination Chemistry with Zirconium(IV): Unexpected Deprotonation-Lithiation Sequence with a Mesitylaminothiophene Precursor},
	journal = {Organometallics},
	volume = {28},
	number = {17},
	year = {2009},
	note = {ISI Document Delivery No.: 489MMTimes Cited: 1Cited Reference Count: 43Menard, Gabriel Jong, Howard Fryzuk, Michael D.},
	month = {Sep},
	pages = {5253-5260},
	type = {Article},
	abstract = {The synthesis and characterization of the thiophene-bridged diamidophosphine proligand [NPN]H-S(2) (2) (where [NPN]H-S(2) = {[N-(2,4,6-Me3C6H2)(3-NH-SC4H2-2-)](2)PPh}) along with several [NPN](ZrX2)-Zr-S (X = NMe2, Cl, I) complexes are presented. The ligand precursor [NPN]H-S(2) was prepared from N-(2,4,6-Me3C6H2)(3-NH-4-Br-SC4H2) (1),(BuLi)-Bu-t, and PhPCl2 in Et2O in 50\% yield; the stereochemistry of the ligand precursor was unexpected and likely resulted from a competitive bromine-lithium exchange and deprotonation sequence with the thiophene starting material I and (BuLi)-Bu-t. A mechanism to rationalize the observed stercochemistry of the product is proposed following deuteration experiments. [NPN]Zr-S(NMe2)(2) (8) can be prepared in 80\% yield by the direct reaction of [NPN]H-S(2) and Zr(NMe2)(4) in toluene. Both [NPN](ZrCl2)-Zr-S (9) and [NPN](ZrI2)-Zr-S (10) are prepared in high yield by the reaction of 8 with excess Me3SiCl or Me3SiI, respectively.},
	keywords = {DIARYLAMIDO-PHOSPHINE-LIGANDS, DIRECTED ORTHO-LITHIATION, END-ON, hafnium, HALOGEN EXCHANGE, lithium, METAL-COMPLEXES, MOLECULAR NITROGEN, ON-BOUND DINITROGEN, PALLADIUM-CATALYZED AMINATION, SIDE-ON},
	isbn = {0276-7333},
	url = {<Go to ISI>://000269424200046},
	author = {Menard, G. and Jong, H. and Fryzuk,Michael D.}
}
@article {2637,
	title = {Vanadium treatment of type 2 diabetes: A view to the future},
	journal = {Journal of Inorganic Biochemistry},
	volume = {103},
	number = {4},
	year = {2009},
	note = {ISI Document Delivery No.: 429EUTimes Cited: 20Cited Reference Count: 41Thompson, Katherine H. Lichter, Jay LeBel, Carl Scaife, Michael C. McNeill, John H. Orvig, Chris6th International Vanadium SymposiumJUL 17-19, 2008Lisbon, PORTUGALSp. Iss. SI},
	month = {Apr},
	pages = {554-558},
	type = {Proceedings Paper},
	abstract = {3-Hydroxy-2-methyl-4-pryone and 2-ethyl 3-hydroxy-4-pyrone (maltol and ethyl maltol, respectively) have proven especially suitable a ligands for vanadyl tons, fit potential insulin enhancing agents for diabetes mellitus. Both bis(maltolato)oxovanadium(IV) (BMOV), and the ethylmaltol analog, bis(ethylmaltolato)oxovanadium(IV) (BEOV), have the desired intermediate stability for pro-drug use, and have undergone extensive pie-clinical testing for safety and efficacy. Pharmacokinetic evaluation indicates a pattern of biodistribution consistent with fairly rapid dissociation and uptake, binding to serum transferrin for systemic circulation and transport to tissues, with preferential uptake in bone. These bis-ligand oxovanadium(IV) (VOL2) compounds have a clear advantage over inorganic vanadyl sulfate in terms of bioavailability and pharmaceutical efficacy. BEOV has now completed Phase I and has advanced to Phase II clinical trials. In the Phase I trial, a ran-e of doses horn 10 mg, to 90 mg BEOV, given orally to non-diabetic volunteers, resulted in no adverse effects, all biochemical parameters remained within normal limits. In the Phase IIa trial, BEOV (AKP-020). 20 mg, daily for 28 clays, per os, in seven type 2 diabetic Subjects, was associated with reductions in fasting blood and glucose and \%HbA1c; improved responses to oral glucose tolerance testing, versus, the observed worsening of diabetic symptoms in the two placebo controls. (C) 2009 Elsevier Inc. All rights reserved.},
	keywords = {BIODISTRIBUTION, bis(ethylmaltolato)oxovanadium(IV), BIS(MALTOLATO)OXOVANADIUM(IV), CHEMISTRY, Diabetes mellitus, IN-VIVO, INSULIN SENSITIVITY, MALTOL, METAL-COMPLEXES, RATS, SERUM, SKELETAL-MUSCLE, SULFATE, VANADIUM},
	isbn = {0162-0134},
	url = {<Go to ISI>://000264904400011},
	author = {Thompson, K. H. and Lichter, J. and Lebel, C. and Scaife, M. C. and McNeill, J. H. and Orvig, Chris}
}
@article {2024,
	title = {99m-Technetium carbohydrate conjugates as potential agents in molecular imaging},
	journal = {Chemical Communications},
	number = {41},
	year = {2008},
	note = {ISI Document Delivery No.: 365LHTimes Cited: 19Cited Reference Count: 97Bowen, Meryn L. Orvig, Chris},
	pages = {5077-5091},
	type = {Article},
	abstract = {This feature article covers recent reports of work towards the development of Tc-99m-carbohydrate based agents for use in SPECT imaging, particularly of cancerous tissue. An outline of some of the key biological functions and coordination chemistry of carbohydrates is given, along with an introduction to bioconjugation and molecular imaging. Technetium coordination chemistry and the subset of this involving bioconjugates are discussed before moving into the focus of the article: glycoconjugates of Tc-99m(v) and the more recently developed [Tc-99m(I)(CO)(3)](+). Significant work in the last decade has featured the very attractive [Tc-99m(CO)(3)](+) core, and the ligand sets designed for this core are discussed in detail.},
	keywords = {ANTITUMOR-ACTIVITY, BIFUNCTIONAL CHELATORS, BIOLOGICAL EVALUATION, D-GLUCOSE, IN-VITRO, ISOSTRUCTURAL RE, METAL-COMPLEXES, STRUCTURAL-CHARACTERIZATION, TC-99M COMPLEXES, TRICARBONYL COMPLEXES},
	isbn = {1359-7345},
	url = {<Go to ISI>://000260407400002},
	author = {Bowen, M. L. and Orvig, Chris}
}
@article {1390,
	title = {Carbohydrate-appended 3-hydroxy-4-pyridinone complexes of the [M(CO)(3)](+) core (M) Re, Tc-99m, Re-186)},
	journal = {Bioconjugate Chemistry},
	volume = {17},
	number = {5},
	year = {2006},
	note = {ISI Document Delivery No.: 085LXTimes Cited: 21Cited Reference Count: 69Ferreira, Cara L. Bayly, Simon R. Green, David E. Storr, Tim Barta, Cheri A. Steele, Jennifer Adam, Michael J. Orvig, Chris},
	month = {Sep},
	pages = {1321-1329},
	type = {Article},
	abstract = {This work describes the use of 3-hydroxy-4-pyridinone ligands for binding the [M(CO)(3)](+) core ( M) Re, Tc) in the context of preparing novel Tc( I) and Re( I) glucose conjugates. Five pyridinone ligands bearing pendent carbohydrate moieties, HL1-5, were coordinated to the [M(CO)(3)](+0) core on the macroscopic scale ( M) Re) and on the tracer scale (M) = Tc-99m, Re-186). On the macroscopic scale the complexes, ReL1-5(CO)(3)(H{\O}-2), were thoroughly characterized by mass spectrometry, IR spectroscopy, UV-visible spectroscopy, elemental analysis, and 1D/2D NMR spectroscopy. Characterization confirmed the bidentate coordination of the pyridinone and the pendent nature of the carbohydrate and suggests the presence of a water molecule in the sixth coordination site. In preliminary biological evaluation, both the ligands and complexes were assessed as potential substrates or inhibitors of hexokinase, but showed no activity. Labeling via the [Tc-99m(CO)(3)(H2O)(3)](+) precursor gave the tracer species (TcL1-5)-Tc-99m(CO)(3)(H2O) in high radiochemical yields. Similar high radiochemical yields when labeling with Re-186 were facilitated by in situ preparation of the [Re-186( CO)(3)(H2O)(3)](+) species in the presence of HL1-5 to give (ReL1-5)-Re-186(CO)(3)(H2O). Stability challenges, incubating (TcL1-5)-Tc-99m(CO)(3)(H2O) in the presence of excess cysteine and histidine, confirmed complex stability up to 24 h.},
	keywords = {5-HT1A RECEPTOR, BIFUNCTIONAL LIGAND, BIOMOLECULES, GLUCOSE, IMAGING AGENTS, IN-VITRO, METAL-COMPLEXES, STRUCTURAL-CHARACTERIZATION, TRICARBONYL COMPLEXES, TRIDENTATE LIGANDS},
	isbn = {1043-1802},
	url = {<Go to ISI>://000240606700027},
	author = {Ferreira, C. L. and Bayly, S. R. and Green, D. E. and Storr, T. and Barta, C. A. and Steele, J. and Adam,Michael J. and Orvig, Chris}
}
@article {1390,
	title = {Carbohydrate-appended 3-hydroxy-4-pyridinone complexes of the [M(CO)(3)](+) core (M) Re, Tc-99m, Re-186)},
	journal = {Bioconjugate Chemistry},
	volume = {17},
	number = {5},
	year = {2006},
	note = {ISI Document Delivery No.: 085LXTimes Cited: 21Cited Reference Count: 69Ferreira, Cara L. Bayly, Simon R. Green, David E. Storr, Tim Barta, Cheri A. Steele, Jennifer Adam, Michael J. Orvig, Chris},
	month = {Sep},
	pages = {1321-1329},
	type = {Article},
	abstract = {This work describes the use of 3-hydroxy-4-pyridinone ligands for binding the [M(CO)(3)](+) core ( M) Re, Tc) in the context of preparing novel Tc( I) and Re( I) glucose conjugates. Five pyridinone ligands bearing pendent carbohydrate moieties, HL1-5, were coordinated to the [M(CO)(3)](+0) core on the macroscopic scale ( M) Re) and on the tracer scale (M) = Tc-99m, Re-186). On the macroscopic scale the complexes, ReL1-5(CO)(3)(H{\O}-2), were thoroughly characterized by mass spectrometry, IR spectroscopy, UV-visible spectroscopy, elemental analysis, and 1D/2D NMR spectroscopy. Characterization confirmed the bidentate coordination of the pyridinone and the pendent nature of the carbohydrate and suggests the presence of a water molecule in the sixth coordination site. In preliminary biological evaluation, both the ligands and complexes were assessed as potential substrates or inhibitors of hexokinase, but showed no activity. Labeling via the [Tc-99m(CO)(3)(H2O)(3)](+) precursor gave the tracer species (TcL1-5)-Tc-99m(CO)(3)(H2O) in high radiochemical yields. Similar high radiochemical yields when labeling with Re-186 were facilitated by in situ preparation of the [Re-186( CO)(3)(H2O)(3)](+) species in the presence of HL1-5 to give (ReL1-5)-Re-186(CO)(3)(H2O). Stability challenges, incubating (TcL1-5)-Tc-99m(CO)(3)(H2O) in the presence of excess cysteine and histidine, confirmed complex stability up to 24 h.},
	keywords = {5-HT1A RECEPTOR, BIFUNCTIONAL LIGAND, BIOMOLECULES, GLUCOSE, IMAGING AGENTS, IN-VITRO, METAL-COMPLEXES, STRUCTURAL-CHARACTERIZATION, TRICARBONYL COMPLEXES, TRIDENTATE LIGANDS},
	isbn = {1043-1802},
	url = {<Go to ISI>://000240606700027},
	author = {Ferreira, C. L. and Bayly, S. R. and Green, D. E. and Storr, T. and Barta, C. A. and Steele, J. and Adam,Michael J. and Orvig, Chris}
}
@article {1392,
	title = {Glucosamine conjugates of tricarbonylcyclopentadienyl rhenium(I) and technetium(I) cores},
	journal = {Inorganic Chemistry},
	volume = {45},
	number = {17},
	year = {2006},
	note = {ISI Document Delivery No.: 073DPTimes Cited: 13Cited Reference Count: 43Ferreira, Cara L. Ewart, Charles B. Bayly, Simon R. Patrick, Brian O. Steele, Jennifer Adam, Michael J. Orvig, Chris},
	month = {Aug},
	pages = {6979-6987},
	type = {Article},
	abstract = {To obtain a Tc-99m glucose conjugate for imaging, double-ligand transfer (DLT) and related reactions were examined for the preparation of CpM(CO)(3) (Cp = cyclopentadienyl; M = Re, Tc) complexes with pendant carbohydrates at Cp. Tricarbonyl {N-(1,3,4,6-tetra-O-acetyl-2-amino-2-deoxy-beta-D-glucopyranose) cyclopentadienyl carboxamide} rhenium(I) (1a) and tricarbonyl {N-(2-amino-2-deoxy-beta-D-glucopyranose) cyclopentadienyl carboxamide} rhenium(I) (2a) were prepared. The compounds were fully characterized by mass spectrometry, elemental analysis, IR, and NMR spectroscopy. Full assignment of the NMR spectra verified the pendant nature of the glucosamine moieties in the solution state and that 2a exists as both anomers. The solid-state structure of 2a was determined by X-ray crystallography, again confirming the pendant nature of the glucosamine, but differing from the solution state in that the, anomer crystallized preferentially (93\%). Compound 2a was determined to be a high-affinity competitive inhibitor (K-i = 330 +/- 70 mu M) of the glucose metabolism enzyme hexokinase, demonstrating that it retains certain biological activity. The Tc-99m analogues 1b and 2b were prepared in moderate radiochemical yields by means of the single-ligand transfer (SLT) route, which is more pertinent to radiopharmaceutical synthesis.},
	keywords = {BIOMOLECULES, COORDINATION, CYCLOPENTADIENYL-TRICARBONYL COMPLEXES, DERIVATIVES, FUNCTIONALIZATION, IN-VITRO, METAL-COMPLEXES, RE-186(I), RECEPTOR, TC-99M},
	isbn = {0020-1669},
	url = {<Go to ISI>://000239723300060},
	author = {Ferreira, C. L. and Ewart, C. B. and Bayly, S. R. and Patrick, B. O. and Steele, J. and Adam,Michael J. and Orvig, Chris}
}
@article {1392,
	title = {Glucosamine conjugates of tricarbonylcyclopentadienyl rhenium(I) and technetium(I) cores},
	journal = {Inorganic Chemistry},
	volume = {45},
	number = {17},
	year = {2006},
	note = {ISI Document Delivery No.: 073DPTimes Cited: 13Cited Reference Count: 43Ferreira, Cara L. Ewart, Charles B. Bayly, Simon R. Patrick, Brian O. Steele, Jennifer Adam, Michael J. Orvig, Chris},
	month = {Aug},
	pages = {6979-6987},
	type = {Article},
	abstract = {To obtain a Tc-99m glucose conjugate for imaging, double-ligand transfer (DLT) and related reactions were examined for the preparation of CpM(CO)(3) (Cp = cyclopentadienyl; M = Re, Tc) complexes with pendant carbohydrates at Cp. Tricarbonyl {N-(1,3,4,6-tetra-O-acetyl-2-amino-2-deoxy-beta-D-glucopyranose) cyclopentadienyl carboxamide} rhenium(I) (1a) and tricarbonyl {N-(2-amino-2-deoxy-beta-D-glucopyranose) cyclopentadienyl carboxamide} rhenium(I) (2a) were prepared. The compounds were fully characterized by mass spectrometry, elemental analysis, IR, and NMR spectroscopy. Full assignment of the NMR spectra verified the pendant nature of the glucosamine moieties in the solution state and that 2a exists as both anomers. The solid-state structure of 2a was determined by X-ray crystallography, again confirming the pendant nature of the glucosamine, but differing from the solution state in that the, anomer crystallized preferentially (93\%). Compound 2a was determined to be a high-affinity competitive inhibitor (K-i = 330 +/- 70 mu M) of the glucose metabolism enzyme hexokinase, demonstrating that it retains certain biological activity. The Tc-99m analogues 1b and 2b were prepared in moderate radiochemical yields by means of the single-ligand transfer (SLT) route, which is more pertinent to radiopharmaceutical synthesis.},
	keywords = {BIOMOLECULES, COORDINATION, CYCLOPENTADIENYL-TRICARBONYL COMPLEXES, DERIVATIVES, FUNCTIONALIZATION, IN-VITRO, METAL-COMPLEXES, RE-186(I), RECEPTOR, TC-99M},
	isbn = {0020-1669},
	url = {<Go to ISI>://000239723300060},
	author = {Ferreira, C. L. and Ewart, C. B. and Bayly, S. R. and Patrick, B. O. and Steele, J. and Adam,Michael J. and Orvig, Chris}
}
@article {1573,
	title = {Inner-sphere two-electron reduction leads to cleavage and functionalization of coordinated dinitrogen},
	journal = {Proceedings of the National Academy of Sciences of the United States of America},
	volume = {103},
	number = {46},
	year = {2006},
	note = {ISI Document Delivery No.: 108OPTimes Cited: 14Cited Reference Count: 55Spencer, Liam P. MacKay, Bruce A. Patrick, Brian O. Fryzuk, Michael D.},
	month = {Nov},
	pages = {17094-17098},
	type = {Article},
	abstract = {Activation of molecular nitrogen by transition metal complexes is an area of current interest as investigations using the inert N-2 molecule to produce higher-value organonitrogen compounds intensify. In an attempt to extend the addition of hydride reagents E-H (where E = BR2, AIR(2), and SiR3) to the dinitrogen complex ([NPN]Ta)(2)(mu-H)(2)(mu-eta(2):eta(2)-N-2) [1; where NPN = (PhNSiMe2CH2)(2)PPh], the reaction with zirconocene chlorohydride, [Cp2Zr(Cl)H](x), was examined. The crystalline product formed in 35\% yield was determined to be ([NP(N)N]Ta)(mu-H)(2)(mu-N)(Ta[NPN])(ZrCP2) (2) in which the coordinated N-2 has been cleaved to form a phosphinimide bridging between Ta and Zr and a triply bridging nitride. The mechanism of this reaction was examined to determine the fate of the chloride and hydricle ligands attached to Zr in the starting zirconocene reagent. Using the zirconocene dihydride dimer ([Cp2ZrH2](2)), a higher yield of 2 was obtained (76\%), and H-2 was also observed by H-1 NMR spectroscopy. To probe the origin of the eliminated H-2, the dideuterated dinitrogen complex ([NPN]Ta)(2)(tLID)(2)(mu-eta(1):n(2)-N-2) (d(2)-1) was allowed to react with ([CP2ZrH2](2)), which resulted in the formation of ([NP(N)N]Ta)(mu-D)(2)(mu-N)(Ta[NPN]) (ZrCP2), (d(2)-2), with no evidence of hydrogen for deuterium scrambling between the starting zirconocene dihydride and the ditantalum dinitrogen complex. Studies into the use of preformed Zr(II) and Ti(II) reagents were also performed. The proposed mechanism involves initial adduct formation that facilitates inner-sphere electron transfer to cleave the N-N bond to form a species with bridging nitrides, one of which is transformed by nucleophilic attack of a phosphine donor to generate the observed phosphinimide.},
	keywords = {BOND-CLEAVAGE, BRIDGING N-2 UNIT, CLEAVAGE, COMPLEXES, dinitrogen coordination, END-ON, METAL-COMPLEXES, MOLECULAR, MOLYBDENUM-IRON PROTEIN, NITROGEN, nitrogen fixation, nitrogen-nitrogen bond, PHOSPHINIMIDE COMPLEXES, SIDE-ON, TANTALUM COMPLEX, TUNGSTEN},
	isbn = {0027-8424},
	url = {<Go to ISI>://000242249400008},
	author = {Spencer, L. P. and MacKay, B. A. and Patrick, B. O. and Fryzuk,Michael D.}
}
@article {1646,
	title = {New rhodium(I) carbene complexes from carbene transfer reactions},
	journal = {Organometallics},
	volume = {25},
	number = {9},
	year = {2006},
	note = {ISI Document Delivery No.: 035AZTimes Cited: 25Cited Reference Count: 41},
	month = {Apr},
	pages = {2359-2363},
	type = {Article},
	abstract = {The Rh(I) complexes RhCl(diene)(NHC) have been synthesized from Ag(I) carbene precursors, where NHC is one of the N-heterocyclic carbenes 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene (IPr), 1,3bis(2,4,6-trimethylphenyl)imidazol-2-ylidene (IMes), 3-methyl-1-phenacylimidazol-2-ylidene (MAI), and 3-methyl-1-picolylimidazol-2-ylidene (MPI), and diene is either NBD or COD. The complexes are characterized by elemental analysis, H-1 NMR and IR spectroscopies, mass spectrometry, and, in the case of RhCl(NBD)(IMes) and RhCl(COD)(MAI), X-ray crystallography. The new Ag(I) carbene complexes [Ag(IPr)(2)]PF6 and [Ag(IMeS)(2)]PF6 are also reported.},
	keywords = {APPLICATION, CATALYTIC, COUPLING, EFFICIENT CATALYSTS, IRIDIUM, LIGAND, METAL-COMPLEXES, N-heterocyclic carbene, NUCLEOPHILIC CARBENE, OLEFIN METATHESIS, REACTIONS, SILVER(I)},
	isbn = {0276-7333},
	url = {<Go to ISI>://000236973500033},
	author = {Yu, X. Y. and Patrick, B. O. and James, Brian R.}
}
@article {1605,
	title = {Ortho-selective C-Hactivation of substituted benzenes effected by a tungsten alkylidene complex without substituent coordination},
	journal = {Organometallics},
	volume = {25},
	number = {17},
	year = {2006},
	note = {ISI Document Delivery No.: 070PZTimes Cited: 13Cited Reference Count: 36Tsang, Jenkins Y. K. Buschhaus, Miriam S. A. Legzdins, Peter Patrick, Brian O.},
	month = {Aug},
	pages = {4215-4225},
	type = {Article},
	abstract = {{Gentle thermolysis of the bis(neopentyl) complex Cp*W(NO)(CH2CMe3)(2) (1) at 70 degrees C in various substituted benzenes results in the loss of neopentane and the generation of the transient alkylidene complex Cp*W(NO)(=CHCMe3) (A), which subsequently effects single C-H bond activations of the benzenes. These activations exhibit a pronounced selectivity for the C-H linkages ortho to the benzene substituents. Thus, thermal reactions of 1 with C6H5X lead to the preferential formation of the corresponding Cp*W( NO)(CH2CMe3)(o-C6H4X) complexes, the ortho-selectivity, i. e.},
	keywords = {CLEAVAGE, CRYSTAL-STRUCTURE, ELIMINATION, H BONDS, IRIDIUM, MECHANISM, METAL-COMPLEXES, {ARYL},
	isbn = {0276-7333},
	url = {<Go to ISI>://000239536800028},
	author = {Tsang, J. Y. K. and Buschhaus, M. S. A. and Legzdins,Peter and Patrick, B. O.}
}
@article {1475,
	title = {Substituent effects in the hydrosilylation of coordinated dinitrogen in a ditantalum complex: Cleavage and functionalization of N-2},
	journal = {Journal of the American Chemical Society},
	volume = {128},
	number = {29},
	year = {2006},
	note = {ISI Document Delivery No.: 064WLTimes Cited: 19Cited Reference Count: 44MacKay, Bruce A. Munha, Rui F. Fryzuk, Michael D.},
	month = {Jul},
	pages = {9472-9483},
	type = {Article},
	abstract = {{The dinitrogen complex ([NPN]Ta)(2)(mu(1)-eta(2):eta(2)-N-2)(mu-H)(2), 1, (where [NPN] = (PhNSiMe2CH2)(2)PPh) undergoes hydrosilylation with primary and secondary alkyl- and arylsilanes, giving a new N-Si bond and a new terminal tantalum hydride derived from one Si-H unit. Various primary silanes can be employed to give isolable complexes of the general formula ([NPN]TaH)(mu-N-N-SiHnR3-n)(mu-H)(2)(Ta[NPN]) (5},
	keywords = {CATALYTIC-REDUCTION, END-ON, LIGAND, METAL-COMPLEXES, MOLECULAR NITROGEN, MOLYBDENUM, N BOND-CLEAVAGE, SIDE-ON, TERMINAL ALKYNES, TRIAMIDOAMINE COMPLEXES},
	isbn = {0002-7863},
	url = {<Go to ISI>://000239120700063},
	author = {MacKay, B. A. and Munha, R. F. and Fryzuk,Michael D.}
}
@article {1105,
	title = {Characterization of a rhodium(III)-imine-orthometalated imine complex: Reversible C-H activation of a coordinated imine},
	journal = {Organometallics},
	volume = {24},
	number = {15},
	year = {2005},
	note = {ISI Document Delivery No.: 945IGTimes Cited: 13Cited Reference Count: 40},
	month = {Jul},
	pages = {3753-3757},
	type = {Article},
	abstract = {Solutions of cis-[Rh(PPh3)(2)(solv)(2)]PF6 (solv = acetone or MeOH) react at room temperature under Ar with benzophenone imine to yield cis- [Rh(PPh3)(2)(eta(1)-NH=CPh2)(2)]PF6 (3), but depending on reaction conditions, one of the imine ligands undergoes orthometalation to give [RhH{NH=C(Ph)(o-C6H4)}(HN=CPh2)(PPh3)(2)]PF6 (2) with trans-phosphines; this is the first recorded complex containing an imine in its eta(1)-form and as an eta(2)-moiety formed via orthometalation. Complexes 2 and 3 are characterized by elemental analysis, H-1 and P-31-{H-1} NMR spectroscopy, and, in the case of 2, an X-ray crystal structure.},
	keywords = {BEHAVIOR, BONDS, CATIONIC COMPLEXES, COMPLEXES, HYDROGENATION, METAL-COMPLEXES, OXIDATIVE ADDITION, RHODIUM(III), semicarbazones, TERDENTATE NITROGEN LIGANDS, UNIT},
	isbn = {0276-7333},
	url = {<Go to ISI>://000230495600021},
	author = {Ezhova, M. B. and Patrick, B. O. and James, Brian R.}
}
@article {1252,
	title = {Cleavage of hydrazine and 1,1-dimethylhydrazine by dinuclear tantalum hydrides: Formation of imides, nitrides, and N,N-dimethylamine},
	journal = {Journal of the American Chemical Society},
	volume = {127},
	number = {2},
	year = {2005},
	note = {ISI Document Delivery No.: 887RZTimes Cited: 11Cited Reference Count: 21},
	month = {Jan},
	pages = {500-501},
	type = {Article},
	keywords = {BRIDGING N-2 UNIT, COORDINATION, DINITROGEN COMPLEX, END-ON, FUNCTIONALIZATION, LIGAND, METAL-COMPLEXES, N-N BOND, REDUCTIVE CLEAVAGE, SIDE-ON},
	isbn = {0002-7863},
	url = {<Go to ISI>://000226324500013},
	author = {Shaver, M. P. and Fryzuk,Michael D.}
}
@article {1185,
	title = {Functionalization and cleavage of coordinated dinitrogen via hydroboration using primary and secondary boranes},
	journal = {Canadian Journal of Chemistry-Revue Canadienne De Chimie},
	volume = {83},
	number = {4},
	year = {2005},
	note = {ISI Document Delivery No.: 921DLTimes Cited: 14Cited Reference Count: 30},
	month = {Apr},
	pages = {315-323},
	type = {Article},
	abstract = {The reaction of the side-on, end-on ditantalum dinitrogen complex ([NPN]Ta)(2)(mu-eta(1):eta(2)-N-2)(mu-H)(2) (where NPN = PhP(CH2SiMe2NPh)(2)) with a variety of secondary and primary boranes is reported. With 9-BBN, hydroboration of the Ta2N2 unit occurs via B-H addition, which in turn triggers a cascade of reactions that result in N-N bond cleavage, ancillary ligand rearrangement involving silicon group migration, and finally elimination of benzene from the N-Ph group and a B-H moiety to generate the imide-nitride derivative. In the presence of excess 9-BBN, the Lewis acid - base adduct of the imide-nitride ([NP mu-N]Ta(=NBC8H14)(mu-NB(H)C8H14)Ta[NPN]) is formed. A similar set of reactions is observed for dicyclohexylborane (Cy2BH), which hydroborates the dinitrogen complex to generate [NPN]Ta(H)(mu-eta(1):eta(2)-NNBCy2)(mu-H)(2)Ta[NPN], followed by loss of H-2 and silicon group migration to yield the imide-nitride [NP mu-N]Ta(=NBCy2)(mu-N)(Ta[NPN]. With thexyl borane (H2BCMe2CHMe2), a similar sequence of reactions is suggested starting with hydroboration to generate [NPN]Ta(H)(mu-eta(1):eta(2)-NNB(H)C6H13)(mu-H)(2)Ta[NPN], followed by loss of H-2 and ancillary ligand rearrangement. When bis(pentafluorophenyl)borane (HB(C6F5)(2)) is used, no hydroboration of coordinated N-2 is observed, rather simple adduct formation to give ([NPN]Ta)(2)(mu-eta(1):eta(2)-NN-B(H)(C6F5)(2))(mu-H)(2) occurs.},
	keywords = {ACTIVATION, ammonia, CHEMISTRY, DINITROGEN, END-ON, FIXATION, hydroboration, METAL-COMPLEXES, MOLECULAR NITROGEN, MOLYBDENUM, N-2, N-N bond cleavage, SIDE-ON, tantalum},
	isbn = {0008-4042},
	url = {<Go to ISI>://000228744300008},
	author = {MacKay, B. A. and Johnson, S. A. and Patrick, B. O. and Fryzuk,Michael D.}
}
@article {1208,
	title = {Group 13 and lanthanide complexes with mixed O,S anionic ligands derived from maltol},
	journal = {Inorganic Chemistry},
	volume = {44},
	number = {8},
	year = {2005},
	note = {ISI Document Delivery No.: 916GWTimes Cited: 23Cited Reference Count: 61},
	month = {Apr},
	pages = {2666-2677},
	type = {Article},
	abstract = {Four mixed O,S binding ligand precursors derived from maltol (3-hydroxy-2-methyl-4-pyrone) have been chelated to gallium(III), indium(III), and lanthanide(III) ions to yield a series of metal complexes. The four ligand precursors include two pyranthiones, 3-hydroxy-2-methyl-4-pyranthione, commonly known as thiomaltol (Htma), and 2-ethyl-3-hydroxy-4-pyranthione, commonly known as ethylthiornaltol (Hetma), and two pyridinethiones, 3-hydroxy-2-methyl-4(H)-pyridinethione (Hmppt) and 3-hydroxy-1,2-dimethyl-4-pyridinethione (Hdppt). Dimeric forms of the pyridinethiones, Hmppt dimer and Hdppt dimer, were also isolated and characterized. Complete characterization of the monomeric organic compounds is reported including acidity constants and crystal structures of Htma, Hetma, and Hdppt dimer. Reacting the four monomeric ligand precursors with Ga3+ and In3+ ions yielded new tris(bidentate ligand) complexes. X-ray-quality crystals of the fac isomer of Ga(tma)(3) were also obtained. New complexes with a range of anthanicles (Ln(3+)) were also synthesized with the two pyranthiones, Htma and Hetma. The synthesis reactions yielded complexes of the type LnL(3)center dot xH(2)O and LnL(2)(OH)center dot xH(2)O, as indicated by elemental analysis and spectroscopic evidence such as mass spectral data and IR and NMR spectra.},
	keywords = {ACID, aluminum, CHELATE COMPLEXES, CHEMISTRY, CRYSTAL-STRUCTURE, DIAGNOSTIC-TOOLS, gallium, indium, METAL-COMPLEXES, RADIOPHARMACEUTICALS},
	isbn = {0020-1669},
	url = {<Go to ISI>://000228374400017},
	author = {Monga, V. and Patrick, B. O. and Orvig, Chris}
}
@article {1208,
	title = {Group 13 and lanthanide complexes with mixed O,S anionic ligands derived from maltol},
	journal = {Inorganic Chemistry},
	volume = {44},
	number = {8},
	year = {2005},
	note = {ISI Document Delivery No.: 916GWTimes Cited: 23Cited Reference Count: 61},
	month = {Apr},
	pages = {2666-2677},
	type = {Article},
	abstract = {Four mixed O,S binding ligand precursors derived from maltol (3-hydroxy-2-methyl-4-pyrone) have been chelated to gallium(III), indium(III), and lanthanide(III) ions to yield a series of metal complexes. The four ligand precursors include two pyranthiones, 3-hydroxy-2-methyl-4-pyranthione, commonly known as thiomaltol (Htma), and 2-ethyl-3-hydroxy-4-pyranthione, commonly known as ethylthiornaltol (Hetma), and two pyridinethiones, 3-hydroxy-2-methyl-4(H)-pyridinethione (Hmppt) and 3-hydroxy-1,2-dimethyl-4-pyridinethione (Hdppt). Dimeric forms of the pyridinethiones, Hmppt dimer and Hdppt dimer, were also isolated and characterized. Complete characterization of the monomeric organic compounds is reported including acidity constants and crystal structures of Htma, Hetma, and Hdppt dimer. Reacting the four monomeric ligand precursors with Ga3+ and In3+ ions yielded new tris(bidentate ligand) complexes. X-ray-quality crystals of the fac isomer of Ga(tma)(3) were also obtained. New complexes with a range of anthanicles (Ln(3+)) were also synthesized with the two pyranthiones, Htma and Hetma. The synthesis reactions yielded complexes of the type LnL(3)center dot xH(2)O and LnL(2)(OH)center dot xH(2)O, as indicated by elemental analysis and spectroscopic evidence such as mass spectral data and IR and NMR spectra.},
	keywords = {ACID, aluminum, CHELATE COMPLEXES, CHEMISTRY, CRYSTAL-STRUCTURE, DIAGNOSTIC-TOOLS, gallium, indium, METAL-COMPLEXES, RADIOPHARMACEUTICALS},
	isbn = {0020-1669},
	url = {<Go to ISI>://000228374400017},
	author = {Monga, V. and Patrick, B. O. and Orvig, Chris}
}
@article {1186,
	title = {Hydroalumination of a dinuclear tantalum dinitrogen complex: N-N bond cleavage and ancillary ligand rearrangement},
	journal = {Organometallics},
	volume = {24},
	number = {16},
	year = {2005},
	note = {ISI Document Delivery No.: 949ZKTimes Cited: 15Cited Reference Count: 32},
	month = {Aug},
	pages = {3836-3841},
	type = {Article},
	abstract = {The addition of diisobutylaluminum hydride (DIBAL) to the side-on end-on dinitrogen complex ([NPN]Ta)(2)(mu-eta(1):eta(2)-N-2)(mu-H)(2), 1 (where [NPN] = (PhNSiMe2CH2)(2)PPh), is described. The two end products are diastereomeric rotational isomers in which N-N bond cleavage has occurred with an Al(Bu-i)H group attached to one of the nitride atoms. The reaction proceeds through addition of DIBAL to 1 to generate a thermally sensitive intermediate that has been characterized in solution as the result of Al-H addition across the TaN2 moiety, namely, ([NPN]TaH)(mu-eta(1):eta(2)-NNA1(i)Bu(2))(mu-H)(2)(Ta[NPN), 2. This material subsequently rearranges via a second thermally labile intermediate to ultimately generate two diastereomeric end products that show N-N bond cleavage, loss of H-2, loss of an aluminum isobutyl group, and NPN ligand migration from tantalum to aluminum. Both of these complexes have been isolated in crystalline form and analyzed by single-crystal X-ray diffraction. The second thermally sensitive intermediate has been characterized on the basis of multinuclear NMR spectroscopy as ([NPN]TaH)(mu-eta(1):eta(2)-(NNAlBu)-Bu-i(mu-H))(mu-H)(2)(Ta[NPN), 3.},
	keywords = {ACTIVATION, ATMOSPHERIC NITROGEN, CHEMISTRY, COORDINATED DINITROGEN, END-ON, FUNCTIONALIZATION, METAL-COMPLEXES, MOLECULAR NITROGEN, N-2, SIDE-ON},
	isbn = {0276-7333},
	url = {<Go to ISI>://000230827200007},
	author = {MacKay, B. A. and Patrick, B. O. and Fryzuk,Michael D.}
}
@article {1187,
	title = {A new arene-bridged diamidophosphine ligand and its coordination chemistry with zirconium(IV)},
	journal = {Organometallics},
	volume = {24},
	number = {6},
	year = {2005},
	note = {ISI Document Delivery No.: 904YFTimes Cited: 15Cited Reference Count: 48},
	month = {Mar},
	pages = {1112-1118},
	type = {Article},
	abstract = {The arene-bridged dilithium diamidophosphine ligand, [(2,4,6-Me3C6H2)NLi-2-(5-MeC6H3)](2)PPh, [NPN]*Li-2, was prepared from (2,4,6-Me3C6H2)(2-Br-4-MeC6H3)NH, (BuLi)-Bu-n, and PhPCl2 in Et2O and isolated as a dioxane adduct in similar to 85\% yield. The solid-state structure of [NPN]*Li-2(THF)2 as determined by X-ray diffraction shows both lithiums bridged by the amido nitrogens with one Li ion coordinated to the phosphine donor. The reaction of [NPN]*H-2 and Zr(NMe2)(4) in toluene produced [NPN]*Zr(NMe2)(2) in 90\% isolated yield. Addition of excess Me3SiCl to [NPN]*Zr(NMe2)(2) converts it to [NPN]*ZrCl2 in high yield. The solid-state structure of [NPN] *ZrCl2 as determined by X-ray diffraction shows the Zr center is a distorted trigonal bipyramid with the phosphine and the chloride apical. The ortho-Me{\textquoteright}s on the N-mesityl moiety are inequivalent in both the Li and Zr complexes of [NPN]* by NMR spectroscopy, while in [NPN]*H-2 MesN ortho-Me{\textquoteright}s appear as broad singlets. VT-NMR of [NPN]*H-2 indicated that Delta G(rot)(double dagger) of MesC(ipso)-N is approximately 15.5 +/- 0.3 kcal mol(-1). The thermally labile and light-sensitive zirconium dimethyl complex [NPN]*ZrMe2 was prepared from [NPN]*ZrCl2 and MeMgCl in Et2O in 80\% yield.},
	keywords = {CLEAVAGE, COMPLEX, COUPLING REACTIONS, DINITROGEN LIGAND, END-ON, METAL-COMPLEXES, MOLECULAR NITROGEN, N-2 UNIT, palladium, SIDE-ON, tantalum},
	isbn = {0276-7333},
	url = {<Go to ISI>://000227533800014},
	author = {MacLachlan, E. A. and Fryzuk,Michael D.}
}
@article {1116,
	title = {Synthesis, structure, and computational studies of soluble conjugated multidentate macrocycles},
	journal = {J. Org. Chem.},
	volume = {70},
	number = {20},
	year = {2005},
	note = {ISI Document Delivery No.: 968MOTimes Cited: 47Cited Reference Count: 67},
	month = {Sep},
	pages = {7936-7946},
	type = {Article},
	abstract = {<p>Conjugated, shape-persistent macrocycles based on [3 + 3] Schiff-base condensation are of interest for supramolecular materials. In an effort to develop new discotic liquid crystals based on these compounds, a series of macrocycles with peripheral alkoxy groups of varying length have been prepared. The synthesis and mechanism of formation have been probed by isolation of oligomeric intermediates. A single-crystal X-ray diffraction study of one macrocycle revealed a nonplanar, strongly hydrogen-bonded structure. To our surprise, even with very long substituents, the macrocycles were not liquid crystalline. This has been rationalized by ab initio calculations that indicate the macrocycles are undergoing rotation of the dibydroxydiiminobenzene rings that may not allow a stable discotic liquid crystalline phase. These results provide new insight into the formation and properties of these large macrocycles and may provide guidance to developing stable liquid crystalline materials in the future.</p>},
	keywords = {CHEMISTRY, CRYSTAL-STRUCTURE, cyclodextrin, LIGANDS, LIQUID-CRYSTAL, METAL-COMPLEXES, porphyrins, RECEPTORS, SCHIFF-BASE MACROCYCLES, SHAPE-PERSISTENT MACROCYCLES, supramolecular},
	isbn = {0022-3263},
	url = {<Go to ISI>://000232166800015},
	author = {Gallant, A. J. and J. K.-H. Hui and Zahariev, F. E. and Y. A. Wang* and M. J. MacLachlan*}
}
@article {947,
	title = {Carbon-nitrogen bond formation via the reaction of terminal alkynes with a dinuclear side-on dinitrogen complex},
	journal = {Journal of the American Chemical Society},
	volume = {126},
	number = {31},
	year = {2004},
	note = {ISI Document Delivery No.: 843TSTimes Cited: 27Cited Reference Count: 21},
	month = {Aug},
	pages = {9480-9481},
	type = {Article},
	keywords = {ACTIVATION, COORDINATION, FIXATION, FUNCTIONALIZATION, HETEROCYCLES, HYDROAMINATION, METAL-COMPLEXES, MOLECULAR NITROGEN, MOLYBDENUM, N-2},
	isbn = {0002-7863},
	url = {<Go to ISI>://000223110100007},
	author = {Morello, L. and Love, J. B. and Patrick, B. O. and Fryzuk,Michael D.}
}
@article {1014,
	title = {Mechanisms of Staudinger reactions within density functional theory},
	journal = {J. Org. Chem.},
	volume = {69},
	number = {13},
	year = {2004},
	note = {ISI Document Delivery No.: 831IDTimes Cited: 25Cited Reference Count: 96},
	month = {Jun},
	pages = {4299-4308},
	type = {Article},
	abstract = {<p>The Staudinger reactions of substituted phosphanes and azides have been investigated by using density functional theory. Four different initial reaction mechanisms have been found. All systems studied go through a cis-transition state rather than a trans-transition state or a one-step transition state. The one-step pathway of the phosphorus atom attacking the substituted nitrogen atom is always unfavorable energetically. Depending on the substituents on the azide and the phosphane, the reaction mechanism with the lowest initial reaction barrier can be classified into three categories: (1) like the parent reaction, PH3 + N3H, the reaction goes through a cis-transition state, approaches a cis-intermediate, overcomes a PN-bond-shifting transition state, reaches a four-membered ring intermediate, dissociates N-2 by overcoming a small barrier, and results in the final products: N-2 and a phosphazene; (2) once reaching the cis-intermediate, the reaction goes through the N-2-eliminating transition state and produces the final products; (3) the reaction has a concerted initial cis-transition state, in which the phosphorus atom attacks the first and the third nitrogen atoms of the azide simultaneously and reaches an intermediate, and then the reaction goes through similar steps of the first reaction mechanism. In contrast to the previous predictions on the relative stability of the unsubstituted cis-configured phosphazide intermediate and the unsubstituted trans-configured phosphazide intermediate, the total energy of the substituted trans-configured phosphazide intermediate is close to that of the substituted cis-configured phosphazide intermediate. The preference of the initial cis-transition state reaction pathway is thoroughly discussed. The relative stability of the cis- and the trans-intermediates is explored and analyzed with the aid of molecular orbitals. The effects of substituents and solvent effects on the reaction mechanisms of the Staudinger reactions are discussed in detail.</p>},
	keywords = {AB-INITIO, GAS-PHASE, GAUSSIAN-TYPE BASIS, GOLD(I) COMPLEXES, METAL-COMPLEXES, MOLECULAR-ORBITAL METHODS, ORGANIC-MOLECULES, PHOSPHINIMIDE COMPLEXES, TRIAZADIENYL FLUORIDE, X-RAY CRYSTAL},
	isbn = {0022-3263},
	url = {<Go to ISI>://000222187200003},
	author = {Tian, W. Q. and Y. A. Wang*}
}
@article {684,
	title = {Amine products and catalyst poisoning in the homogeneous H-2 hydrogenation of Imines catalyzed by the [Rh(COD)(PPh3)(2)]PF6 precursor},
	journal = {Organometallics},
	volume = {22},
	number = {6},
	year = {2003},
	note = {ISI Document Delivery No.: 654QJTimes Cited: 23Cited Reference Count: 14},
	month = {Mar},
	pages = {1177-1179},
	type = {Article},
	abstract = {The H-2 hydrogenations of PhN=CHPh and PhCH2N=CHPh are catalyzed by the precursor [Rh(COD)(PPh3)(2)]PF6. However, the amine product PhNHCH2Ph poisons the catalyst by coordination to the Rh through an arene moiety, while the other amine product, (PhCH2)(2)NH, forms a labile N-bonded species that does not poison the catalyst system.},
	keywords = {LIGANDS, METAL-COMPLEXES, rhodium},
	isbn = {0276-7333},
	url = {<Go to ISI>://000181507300003},
	author = {Marcazzan, P. and Patrick, B. O. and James, Brian R.}
}
@article {537,
	title = {Parallel modes of C-H bond activation initiated by Cp*Mo(NO)(CH2CMe3)(C6H5) at ambient temperatures},
	journal = {Journal of the American Chemical Society},
	volume = {124},
	number = {33},
	year = {2002},
	note = {ISI Document Delivery No.: 584EVTimes Cited: 15Cited Reference Count: 32},
	month = {Aug},
	pages = {9680-9681},
	type = {Article},
	keywords = {ALKANES, ARYNE COMPLEXES, CHEMISTRY, HYDROCARBONS, INTERMEDIATE, METAL-COMPLEXES, MOLYBDENUM, REACTIVITY, THERMOLYSIS, TUNGSTEN ALKYLIDENE COMPLEXES},
	isbn = {0002-7863},
	url = {<Go to ISI>://000177455000012},
	author = {Wada, K. and Pamplin, C. B. and Legzdins,Peter}
}
@article {440,
	title = {Synthesis and structure of dimeric Rh-bis(tertiary phosphine) complexes, exceptionally useful synthetic precursors},
	journal = {Comptes Rendus Chimie},
	volume = {5},
	number = {5},
	year = {2002},
	note = {ISI Document Delivery No.: 617WPTimes Cited: 12Cited Reference Count: 35},
	month = {May},
	pages = {373-378},
	type = {Article},
	abstract = {Removal of the MeOH and hydrogen from the known cis, trans, cis-Rh-111-dihydrido complexes [Rh(H)(2)(PR3)(2)(MeOH)(2)]PF6 (R= Ph, p-tolyl) results in formation of the dimeric species [Rh-2(PR3)(4)][PF6](2); X-ray analysis shows the complexes to be [(Ph3P)Rh(mu-PhPPh2)](2)(PF6](2) (and the p-tolyl analogue) containing bridged eta(6)-arene moieties, while H-1 and C-13 NMR data in CD2Cl2 provide evidence for Teta(4)-coordination of the arene within the dimer. In more strongly coordinating solvents, formation of cis-{Rh(PR3)(2)(solvent)(2)}PF6 is observed, while formation of [(PR3)(2)Rh(eta(6)-toluene)]PF6 is evident in toluene solution, and this exists in equilibrium with the bis(solvent) species in the presence, for example, of acetone or MeOH. At ambient conditions, none of the arene-containing complexes effected catalytic H-2-hydrogenation of toluene.},
	keywords = {arene complexes, CATIONIC RHODIUM COMPLEXES, EXCHANGE, imines, LIGANDS, METAL-COMPLEXES, OLEFINS, PHOSPHINE COMPLEXES, Rh complexes, SELECTIVE HYDROGENATION, X-ray structures},
	isbn = {1631-0748},
	url = {<Go to ISI>://000179384300004},
	author = {Marcazzan, P. and Ezhova, M. B. and Patrick, B. O. and James, Brian R.}
}
@article {5034,
	title = {A highly efficient preparation of N-confused cyclodecapyrroles},
	journal = {Tetrahedron Letters},
	volume = {42},
	number = {19},
	year = {2001},
	note = {ISI Document Delivery No.: 427KUTimes Cited: 4Cited Reference Count: 33},
	month = {May},
	pages = {3263-3265},
	type = {Article},
	abstract = {Cyclodecapyrroles, potential novel host systems, were synthesized in 78-88\% yields by condensation of tripyrrane dialdehyde with bis(5-carboxyl-2,4-dimethyl-pyrrole-3-yl)-methane, ethane, and -propane in the presence of HBr and TFA. (C) 2001 Elsevier Science Ltd. All rights reserved.},
	keywords = {3, 3 {\textquoteright}-dipyrromethane, ANION SENSORS, CALIXPYRROLES, CYCLOOCTAPYRROLES, cyclopolypyrrole, EXPANDED PORPHYRINS, HOST, macrocycle, macrocycles, METAL-COMPLEXES, TRIPYRRANE},
	isbn = {0040-4039},
	url = {<Go to ISI>://000168404000006},
	author = {Chen, Q. Q. and Dolphin, D.}
}
@article {5201,
	title = {Proton- and lanthanide-coordinating properties of the tetraaza macrocycle (EDDA-KA)(2) in aqueous solution},
	journal = {Canadian Journal of Chemistry-Revue Canadienne De Chimie},
	volume = {79},
	number = {5-6},
	year = {2001},
	note = {ISI Document Delivery No.: 456EVTimes Cited: 4Cited Reference Count: 36},
	month = {May},
	pages = {1058-1067},
	type = {Article},
	abstract = {{The new potentially multidentate ligand (EDDA-KA)(2) has been prepared and its acid-base properties determined. Its coordination properties with three lanthanide ions (La3+, Gd3+, and Lu3+) and Fe3+ have been studied in aqueous solution (I = 0.16 M NaCl, 25degreesC) by potentiometric pH, spectrophotometric, and H-1 NMR titrations. In total, eight pK(a) values could be determined by these diverse methods. From the H-1 NMR titrations, all the deprotonation steps could be determined and assigned (in groups). Strong hydrogen bonding among two nitrogen atoms and one oxygen atom on the pyrone ring was observed, and the corresponding pK(a) values were estimated to be 13.2 and 14.0. By comparison with similar systems, an equilibrium constant for the formation of the hydrogen bond was estimated},
	keywords = {ACID-BASE, acidity constants, ALKALINE-EARTH, amino, BINDING-PROPERTIES, carboxylate chelator, CHEMISTRY, CONTRAST AGENTS, DERIVATIVES, DYNAMICS, Fe3+, GADOLINIUM, Gd3+, La3+, Lu3+, METAL-COMPLEXES, STABILITIES, stability constants},
	isbn = {0008-4042},
	url = {<Go to ISI>://000170070900078},
	author = {Song, B. and Kurokawa, G. S. and Liu, S. and Orvig, Chris}
}
@article {4927,
	title = {Homotrinuclear lanthanide(III) arrays: Assembly of and conversion from mononuclear and dinuclear units},
	journal = {Inorganic Chemistry},
	volume = {39},
	number = {3},
	year = {2000},
	note = {ISI Document Delivery No.: 283FQTimes Cited: 48Cited Reference Count: 54},
	month = {Feb},
	pages = {496-507},
	type = {Article},
	abstract = {The reactions of potentially hexadentate H(2)bbpen (N,N{\textquoteright}-bis(2-hydroxybenzyl)-N,N{\textquoteright}-bis(2-pyridylmethyl)ethylenediamine, H(2)L1), H-2(Cl)bbpen (N,N{\textquoteright}-bis(5-chloro-2-hydroxybenzyl)-N,N{\textquoteright}-bis(2-pyridylmethyl)ethylene-di amine. H(2)L2), and H-2(Br)bbpen (N,N{\textquoteright}-bis(5-bromo-2-hydroxybenzyl)-N,N{\textquoteright}-bis(2-pyridylmethyl)ethylenediam ine H(2)L3) with Ln(III) ions in the presence of a base in methanol resulted in three types of complexes: neutral mononuclear ([LnL(NO3)]), monocationic dinuclear ([Ln(2)Ln(2)(NO3)](+)), and monocationic trinuclear ([Ln(3)L(2)(X)(n)-(CH3OH)](+)) when X = bridging (CH3COO-) and bidentate ligands (NO3-, CH3COO-, ClO4-) and n is 4. The formation of a complex depends on the bose (hydroxide or acetate) and the size of the respective Ln(III) ion. All complexes were characterized by infrared spectroscopy, mass spectrometry, and elemental analyses; in some cases, X-ray diffraction studies were also performed. The structures of the neutral mononuclear [Yb(L1)(NO3)], dinuclear [Pr-2(L1)(2)(NO3)(H2O)]NO3.CH3OH and [Gd-2(L1)(2)(NO3)]NO3.CH3OH.3H(2)O, and trinuclear [Gd-3(L3)(2)(CH3- COO)(4)(CH3OH)]ClO4.5CH(3)OH and [Sm-3(L1)(2)(CH3COO)(2)(NO3)(2)(CH3OH)]NO3.CH3OH.3.65H(2)O were solved by X-ray crystallography. The [LnL(NO3)] or [Ln(2)L(2)(NO3)](+) complexes could be converted to [Ln(3)L(2)(X)(n)(CH3-OH)](+) complexes by the addition of 1 equiv of a Ln(III) salt and 2-3 equiv of sodium acetate in methanol. The trinuclear complexes were found to be the most stable of the three types, which was evident from the presence of the intact monocationic high molecular weight parent peaks ([Ln(3)L(2)(X)(n)](+)) in the mass spectra of all the trinuclear complexes and from the ease of conversion from the mononuclear or dinuclear to the trinuclear species. The incompatibility of the ligand denticity with the coordination requirements of the Ln(III) ions was proven to be a useful tool in the construction of multinuclear Ln(III) metal ion arrays.},
	keywords = {AMINE PHENOL LIGANDS, ANTIBODY, COORDINATION, CRYSTAL-STRUCTURE, GADOLINIUM, IONS, METAL-COMPLEXES, MOLECULAR-STRUCTURE, SAMARIUM(III), Schiff-base},
	isbn = {0020-1669},
	url = {<Go to ISI>://000085266100017},
	author = {Setyawati, I. A. and Liu, S. and Rettig, S. J. and Orvig, Chris}
}
@article {4850,
	title = {Structural studies of organoboron compounds, Part 72 - Nitrones and oximes of bifunctional carbonyl compounds and their reaction products with diarylborinic acids. Crystal and molecular structure of examples of five-, six-, and seven-membered boron chelat},
	journal = {Canadian Journal of Chemistry-Revue Canadienne De Chimie},
	volume = {78},
	number = {10},
	year = {2000},
	note = {ISI Document Delivery No.: 366QGTimes Cited: 9Cited Reference Count: 74},
	month = {Oct},
	pages = {1325-1344},
	type = {Article},
	abstract = {{Synthesis has been carried out of diarylboron chelates of 2- and 3-hydroxynitrones, of 2- and 3-hydroxyoximes, and of 2-carboxynitrones and a 2-carboxyoxime. The structures have been determined from spectroscopic data and from X-ray analyses of 5d, 9a, 11b, and 19. Crystals (at 180 K) of 5d are monoclinic},
	keywords = {carboxynitrones, carboxyoximes, CHEMISTRY, COBALT(III), crystal structure, DERIVATIVES, diarylboron chelates, DIPHENYLBORINIC ACID, hydroxynitrones, HYDROXYOXIME STRUCTURE, hydroxyoximes, LIGAND, METAL-COMPLEXES, N-(2-HYDROXYALKYL)NITRONES, ORGANOBORON COMPOUNDS, RING-CHAIN ISOMERISM},
	isbn = {0008-4042},
	url = {<Go to ISI>://000090015600009},
	author = {Kliegel, W. and Lubkowitz, G. and Pokriefke, J. O. and Rettig, S. J. and Trotter, J.}
}
@article {4517,
	title = {Hydrocarbon C-H bond activation by a tungsten acetylene complex},
	journal = {Organometallics},
	volume = {18},
	number = {17},
	year = {1999},
	note = {ISI Document Delivery No.: 230KBTimes Cited: 13Cited Reference Count: 60},
	month = {Aug},
	pages = {3414-3428},
	type = {Article},
	abstract = {Thermal activation of Cp*W(NO)(eta(2)-CPhCH2)(CH2SiMe3) (1) in neat hydrocarbon solutions transiently generates Cp*W(NO)(eta(2)-PhC=CH) (A), which subsequently activates solvent C-H bonds. For example, the thermolysis of 1 in benzene solution generates quantitatively Cp*W(NO)(eta(2)-CPhCH2)(Ph) (2) The thermolysis of 1 in solutions of methyl-substituted arenes such as toluene or p-, m-, or o-xylene provides mixtures of aryl and benzyl vinyl complexes of the general formulas Cp*W(NO)(eta(2)-CPhCH2)(aryl), Cp*W(NO)(eta(2)-CPhCH2)(eta(1)-benzyl), or Cp*W(NO)(eta(2)-benzyl)(eta(1)-CPh=CH2). Similarly, the thermolysis of 1 in (Me3Si)(2)O affords Cp*W(NO)(eta(2)-CPhCH2)(CH2SiMe2OSiMe3) (10). Mechanistic and kinetic studies support the proposal that the formation of A from 1 by elimination of silane is the rate-controlling process in these reactions. Intra- and intermolecular selectivity studies reveal that the strongest C-H bond (yielding the stronger M-C bond) is the preferred site of reactivity, as expected. Dual C-H bond activation of aliphatic hydrocarbons occurs during the thermal activation ;of I in solutions of these substrates. Consequently, metallacycles of the form Cp*W(NO)(eta(2)-CH(eta(2)-Ph)CH2CH(R)CH2) [(11)R = Pr-n; (12)R = Bu-n; (13)R = Bu-t; and (14)R = OEt] result from the dehydrogenation of n-pentane, n-hexane, 2,2-dimethylbutane, and diethyl ether, respectively. This dual C-H activation process displays a selectivity for substrates that contain an ethyl substituent. Dual C-H bond activation of 2,3-dimethyl-2-butene in the presence of 1 under thermolysis conditions regioselectively affords Cp*W(NO)(eta(3)-endo-CH2C(Me)C(Me)CH2(eta(1)-CPhMe)) (15), Attempts to trap acetylene complex A with PNMe3 result in the formation of the metallacyclopropane complex Cp*W(NO)(CH2SiMe3)(eta(2)-CH2CPh(PMe3)) (16). All new complexes have been characterized by conventional spectroscopic methods, and the solid-state molecular structures of compounds 11, 15, and 16 have been established by X-ray diffraction methods.},
	keywords = {ELIMINATION, HYDROGEN-TRANSFER, ISOMERIZATION, LIGAND, METAL-COMPLEXES, MOLECULAR-STRUCTURE, ORGANIC-SYNTHESIS, ORGANOMETALLIC NITROSYL CHEMISTRY, OXIDATIVE ADDITION, REDUCTIVE, R{\textquoteright} =},
	isbn = {0276-7333},
	url = {<Go to ISI>://000082249400023},
	author = {Debad, D. and Legzdins,Peter and Lumb, S. A. and Rettig, S. J. and Batchelor, R. J. and Einstein, F. W. B.}
}
@article {4694,
	title = {An iron-based molecular redox switch as a model for iron release from enterobactin via the salicylate binding mode},
	journal = {Inorganic Chemistry},
	volume = {38},
	number = {22},
	year = {1999},
	note = {ISI Document Delivery No.: 255LLTimes Cited: 18Cited Reference Count: 51},
	month = {Nov},
	pages = {5007-5017},
	type = {Article},
	abstract = {The iron release mechanism from protonated ferric enterobactin [Fe-III(enterobactinH(3))] via the salicylate binding mode was probed. For this purpose, a tripodal dodecadentate Ligand incorporating three salicylamide (OO) and three bipyridine (NN) binding sites was synthesized as well as iron complexes thereof. It was shown that a ferric ion coordinates selectively to the hard salicylamides and a ferrous ion binds to the softer bipyridines. Upon reduction or oxidation, the iron translocates reversibly and intramolecularly from one site to the other, thus displaying switchlike properties. Both states were characterized by cyclic voltammetry and visible and Mossbauer spectroscopy. The Mossbauer spectrum for the ferric complex is fully consistent with that obtained by Pecoraro et al. upon lowering the pH of [Fe-III(enterobactin)](3-) solutions (Pecoraro, V. L., et al. J. Am. Chern. Sec. 1983, 105, 4617), thus supporting the alternative iron release mechanism from enterobactin via the salicylate binding mode.},
	keywords = {COORDINATION CHEMISTRY, ESCHERICHIA-COLI, FERRIC ENTEROBACTIN, IRON(III) COORDINATION, LIGAND, METAL-COMPLEXES, SEQUESTERING AGENTS, SYNTHETIC ANALOGS, TRANSLOCATION, TRANSPORT COMPOUNDS},
	isbn = {0020-1669},
	url = {<Go to ISI>://000083670200015},
	author = {Ward, T. R. and Lutz, A. and Parel, S. P. and Ensling, J. and Gutlich, P. and Buglyo, P. and Orvig, Chris}
}
@article {4520,
	title = {Synthesis and characterization of [RuCl3(P-P)(H2O)] complexes; P-P = achiral or chiral, chelating ditertiary phosphine ligands},
	journal = {Inorganic Chemistry},
	volume = {38},
	number = {23},
	year = {1999},
	note = {ISI Document Delivery No.: 256ZATimes Cited: 29Cited Reference Count: 65},
	month = {Nov},
	pages = {5341-5345},
	type = {Article},
	abstract = {The reaction of the dinuclear [RuCl2(dppb)](2)(mu-dppb) (dppb = 1,4-bis(diphenylphosphino)butane) with Cl-2 in MeOH for similar to 30 min at room temperature gives the bright-red solid mer-RuCl3(dppb)(H2O) (1); Cl-2 treatment for similar to 10 min affords the red-brown, mixed valence complex [RuCl(dppb)](2)(mu-Cl)(3) (2). Controlled bulk coulometric reduction of 50\% of the content of a CH2Cl2 solution of 1 also produces 2, formed by the reaction of 1 with "RuCl2(dppb)" produced in situ during the electrolysis. Complexes 1 and 2 were characterized by spectroscopic techniques [including electron spin resonance (ESR)], magnetic moments and cyclic voltammetry, and the structure of 1 was determined by X-ray diffraction. The structure shows that the aquo ligand forms hydrogen bonds with two cis-chlorine ligands of the neighboring molecule of the complex; this interaction gives rise to exchange coupling between two Ru(III) centers that is reflected in the ESR spectrum. A species 3 analogous to 1 has been obtained with the diop ligand [diop = (2R,3R)- or (2S,3S)-O-isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane] , on using RuCl2(diop)(PPh3) or [RuCl(diop)](2)(mu-Cl)(3) as precursors. The RuCl3(P-P)L complexes (P-P = dppb, diop; L = dimethyl sulfoxide, MeOH) are readily synthesized from 1 or 3.},
	keywords = {ASYMMETRIC HYDROGENATION, BINAP, CATALYSTS, COMPLEXES, CRYSTAL-STRUCTURE, DICARBOXYLATE COMPLEXES, GENERAL-SYNTHESIS, METAL-COMPLEXES, ruthenium, STRUCTURAL CHARACTERIZATION, UNSATURATED CARBOXYLIC-ACIDS},
	isbn = {0020-1669},
	url = {<Go to ISI>://000083755300020},
	author = {Dinelli, L. R. and Batista, A. A. and Wohnrath, K. and de Araujo, M. P. and Queiroz, S. L. and Bonfadini, M. R. and Oliva, G. and Nascimento, O. R. and Cyr, P. W. and Macfarlane, K. S. and James, Brian R.}
}
@article {4280,
	title = {Chelate ring-opening ruthenium complexes: X-ray crystal structure and solution studies of cis,trans-bis(2-dimethyl-aminoethyl)diphenylphosphino(dichloro)ruthenium (II)},
	journal = {Inorganica Chimica Acta},
	volume = {273},
	number = {1-2},
	year = {1998},
	note = {ISI Document Delivery No.: ZP204Times Cited: 13Cited Reference Count: 34XXXIII International Conference on Coordination ChemistryAUG 30-SEP 04, 1998FLORENCE, ITALY},
	month = {May},
	pages = {1-7},
	type = {Proceedings Paper},
	abstract = {{The Ru(II) complex cis,trans-[Ru(Me(2)NCH(2)Ch(2)PPh(2)-P,N)(2)Cl-2] (1) has been characterized in the solid state and in solution. X-ray crystallography showed that complex 1 is monoclinic, space group C-2/c; a = 36.0421},
	keywords = {aminophosphine complexes, chelate ring complexes, crystal structures, DERIVATIVES, IMIDAZOLE, METAL-COMPLEXES, PHOSPHINE-LIGANDS, ruthenium complexes, SERIES},
	isbn = {0020-1693},
	url = {<Go to ISI>://000073728200002},
	author = {Guo, Z. J. and Habtemariam, A. and Sadler, P. J. and James, Brian R.}
}
@article {4325,
	title = {Ligand elaboration mediated by a Cp*W(NO) template: Stepwise incorporation of small molecules into a tungsten vinyl fragment},
	journal = {Organometallics},
	volume = {17},
	number = {5},
	year = {1998},
	note = {ISI Document Delivery No.: ZC012Times Cited: 21Cited Reference Count: 81},
	month = {Mar},
	pages = {854-871},
	type = {Article},
	abstract = {{Thermolysis of the alkyl vinyl complex Cp*W(NO)(CH2SiMe3)(CPh=CH2) (1) in the presence of unsaturated, heteroatom-containing compounds such as esters and nitriles quantitatively affords metallacyclic products of reductive coupling. These are trapped as 18e complexes via either intramolecular rearrangement or intermolecular reaction with added trapping reagents. The nature of these metallacycles is consistent with the intermediacy of the acetylene complex Cp*W(NO)(eta(2)-CPh=CH) (A) derived in situ from the reductive elimination of SiMe4 from 1. With esters ROAc (R = Me, Et), reductive coupling and C-O bond cleavage yields the alkoxide-containing oxametallacyclopentadiene complexes Cp*W-(No)(eta(2)-O=C(Me)CH=CPh)(OR) (2},
	keywords = {ACTIVATION, ALKYNE COMPLEXES, BOND-CLEAVAGE, C-H, INSERTION, KETONE COMPLEXES, METAL-COMPLEXES, ORGANIC-SYNTHESIS, ORGANOMETALLIC NITROSYL CHEMISTRY, RAY CRYSTAL-STRUCTURE, SEQUENTIAL, ZIRCONOCENE COMPLEXES},
	isbn = {0276-7333},
	url = {<Go to ISI>://000072530700014},
	author = {Legzdins,Peter and Lumb, S. A. and Young, V. G.}
}
@article {4143,
	title = {Thermal alkane C-H bond activation by a tungsten alkylidene complex: The reversal of alpha-hydrogen elimination},
	journal = {Journal of the American Chemical Society},
	volume = {119},
	number = {21},
	year = {1997},
	note = {ISI Document Delivery No.: XB674Times Cited: 52Cited Reference Count: 36},
	month = {May},
	pages = {5071-5072},
	type = {Article},
	keywords = {ABSTRACTION, ADDUCTS, ARYL, BINDING, CHEMISTRY, DERIVATIVES, LIGANDS, METAL-COMPLEXES, REACTIVITY, tantalum},
	isbn = {0002-7863},
	url = {<Go to ISI>://A1997XB67400046},
	author = {Tran, E. and Legzdins,Peter}
}
@article {3264,
	title = {THE ONE-STEP SYNTHESIS OF CHIRAL AMINO PHOSPHINO FERROCENES},
	journal = {Journal of Organometallic Chemistry},
	volume = {492},
	number = {2},
	year = {1995},
	note = {ISI Document Delivery No.: QV350Times Cited: 10Cited Reference Count: 24},
	month = {May},
	pages = {157-164},
	type = {Article},
	abstract = {Reaction of the chiral lithium reagent-2-lithio-(alpha-N,N-dimethyl)aminoethylbenzene with 1,1{\textquoteright}-ferrocenediylphenylphosphine gives chiral aminophosphinoferrocenes that contain both chiral carbon and phosphorus centres. Treatment of the ferroceno-phane with 2-lithio-N,N-dimethylaminomethylferrocene followed by hydrolysis gives the product ferrocenyl 2-(dimethylaminomethylferrocenyl) phenylphosphine as a pair of diastereomers. The single crystal structures of compound 3a PdCl2 and compound 4. PdCl2.2CH(2)Cl(2) have been determined. The compounds, 2-(ferrocenylphenylphosphino)-1-(alpha-N, N{\textquoteright}-dimethylaminoethylbenzene)ferrocene, 5 and 1-[2-(alpha-N,N{\textquoteright}-dimethyraminoethylbenzene)phenylphospphino]-1{\textquoteright}-diphenyl phosphinoferrocene, 6a, have also been prepared by minor modifications of the methodology developed.},
	keywords = {<1>FERROCENOPHANES, ASYMMETRIC-SYNTHESIS, CATALYST, chirality, crystal structure, FERROCENE, GRIGNARD, HALIDES, HYDROGENATION, iron, METAL-COMPLEXES, ORGANIC, palladium, PHOSPHORUS, PLANAR CHIRALITY, REAGENTS, SECONDARY},
	isbn = {0022-328X},
	url = {<Go to ISI>://A1995QV35000005},
	author = {Butler, I. R. and Cullen, W. R. and Rettig, S. J. and White, A. S. C.}
}
@article {2736,
	title = {THE REGIOSPECIFIC REACTION OF DIPHENYLACETYLENE WITH BIS(CYCLOPENTADIENYL)(O-FLUOROBENZYNE)TITANIUM - THE CRYSTAL-STRUCTURE OF THE CR(CO)(3), DERIVATIVE OF L,L-BIS(CYCLOPENTADIENYL)2,3-DIPHENYL-7-FLUOROTITANOLE},
	journal = {Journal of Organometallic Chemistry},
	volume = {462},
	number = {1-2},
	year = {1993},
	note = {ISI Document Delivery No.: MM535Times Cited: 0Cited Reference Count: 14},
	month = {Dec},
	pages = {C6-C9},
	type = {Note},
	abstract = {{Diphenylacetylene reacts with the pyrolysis product of bis(cyclopentadienyl)-bis(o-fluorophenyl)titanium to afford predominantly one isomer of the expected titanole. The crystal structure of the Cr(CO)(3) derivative 4 of the titanole shows that the fluorine is in the 7-position indicating that attack of the acetylene on the benzyne intermediate occurs along the less sterically hindered path. Compound 4: monoclinic, Cc},
	keywords = {CYCLOALKYNES, METAL-COMPLEXES},
	isbn = {0022-328X},
	url = {<Go to ISI>://A1993MM53500050},
	author = {Butler, I. R. and Cullen, W. R. and Einstein, F. W. B. and Jones, R. H.}
}
@article {7212,
	title = {REACTION OF FE(ETA-C5H4)2S3 WITH M3(CO)12 (M = RU, OS) - STRUCTURE OF FE(ETA-C5H4S)2RU2(CO)6 AND FE(ETA-C5H4S)2(MU-3-S)OS4(CO)11},
	journal = {Organometallics},
	volume = {11},
	number = {9},
	year = {1992},
	note = {ISI Document Delivery No.: JN066Times Cited: 15Cited Reference Count: 37},
	month = {Sep},
	pages = {3152-3156},
	type = {Note},
	abstract = {{The thermal reaction of 1,2,3-trithia[3]ferrocenophane (1) with Ru3(CO)12 in refluxing hexanes affords the complex Fe(eta-C5H4S)2Ru2(CO)6 (4) in moderate yield. The reaction of 1 with Os3(CO)12 yields Fe(eta-C5H4S)2(S)Os2(CO)6 (5) in low yield in refluxing cyclohexane and four products in moderate to low yields in refluxing toluene. These compounds were identified as the diosmium species Fe(eta-C5H4S)2Os2(CO)8 (6), the triosmium species Fe(eta-C5H4S)2Os3(CO)10 (7), and the tetraosmium species Fe(eta-C5H4S)2(mu-3-S)Os4(CO)11 (8) and Fe(eta-C5H4S)2(mu-3-S)2Os4(CO)10 (9). Only complexes 4 and 8 were characterized by using X-ray crystallography. The common sawhorse geometry is found for 4, with the Fe(eta-C5H4S)2 group bridging the two Ru(CO)3 moieties. The osmium cluster 8 consists of a mu-3-S ligand bridging a spiked triangle of osmium atoms with the Fe(eta-C5H4S)2 ligand bridging the spike Os-Os bond. Both structures have eclipsed and nearly parallel cyclopentadienyl rings. Crystals of 4 are monoclinic, with a = 7.685 (3) angstrom},
	keywords = {BINUCLEAR RUTHENIUM(I), BRIDGED COMPLEXES, CHEMISTRY, CLUSTER, COMPLEXES, CRYSTAL-STRUCTURE, DATIVE BOND, LIGANDS, METAL-COMPLEXES, MOLECULAR-STRUCTURE, SYMMETRICALLY DISUBSTITUTED FERROCENES},
	isbn = {0276-7333},
	url = {<Go to ISI>://A1992JN06600037},
	author = {Cullen, W. R. and Talaba, A. and Rettig, S. J.}
}
