@article {3289,
	title = {ARSENIC BIOMETHYLATION BY THE MICROORGANISM APIOTRICHUM HUMICOLA IN THE PRESENCE OF L-METHIONINE-METHYL-D(3)},
	journal = {Applied Organometallic Chemistry},
	volume = {9},
	number = {7},
	year = {1995},
	note = {ISI Document Delivery No.: TG189Times Cited: 15Cited Reference Count: 273rd International Conference on Environmental and Biological Aspects of Main Group Organometals (ICEBAMO 94)SEP, 1994BORDEAUX, FRANCESoc Francaise Chim, Royal Soc Chem, CNRS, EC Measurement \& Testing Program, French Minist Environm, French Minist Res \& Technol, Univ Bordeaux I, Univ Bordeaux II, IFREMER, INRA, Conseil Reg Aquitaine, Lyonnaise Eaux Dumez Water Co., Thermo Jarell Ash, John Wiley \& Sons, Freund Publ, Elsevier Sci Publ},
	month = {Nov},
	pages = {507-515},
	type = {Proceedings Paper},
	abstract = {The microorganism Apiotrichum humicola (previously known as Candida humicola) grown in the presence of either arsenate, arsenite, methyl-arsonic acid or dimethylarsinic acid, produces arsenic-containing metabolites in the growth medium. When L-methionine-methyl-d(3) is added to the cultures, the CD3 label is incorporated intact into the metabolites to a considerable extent to form deuterated dimethylarsenic and trimethylarsenic species, indicating that S-adenosylmethionine, or some related sulphonium compound, is involved in the biological methylation. Conclusive evidence of CD3 incorporation in the arsenicals found in the growth medium was provided by using a specially developed hydride generation-gas chromatography-mass spectrometry system (HG-GC-MS).},
	keywords = {ARSENATE, ARSENITE, CHROMATOGRAPHY MASS SPECTROMETRY, DIMETHYLARSINIC ACID, EXTRACELLULAR, GAS, HYDRIDE GENERATION, HYDRIDE GENERATION GAS, L-METHIONINE-METHYL-D(3), methylarsonic acid, METHYLATION, MICROORGANISM, REDUCTION, S-ADENOSYLMETHIONINE, THIOLS, TRIMETHYLARSINE OXIDE},
	isbn = {0268-2605},
	url = {<Go to ISI>://A1995TG18900002},
	author = {Cullen, W. R. and Li, H. and Pergantis, S. A. and Eigendorf, G. K. and Mosi, A. A.}
}
@article {2973,
	title = {METHYLATION OF ARSENIC BY ANAEROBIC MICROBIAL CONSORTIA ISOLATED FROM LAKE SEDIMENT},
	journal = {Applied Organometallic Chemistry},
	volume = {8},
	number = {4},
	year = {1994},
	note = {ISI Document Delivery No.: PD643Times Cited: 20Cited Reference Count: 16},
	month = {Jul},
	pages = {415-422},
	type = {Article},
	abstract = {Anaerobic enrichment cultures, isolated from arsenic-contaminated lake sediment in the Canadian sub-arctic and grown in five selective media, methylated arsenate/arsenite to produce mono-, di- and tri-methyl arsenicals. The extent of methylation and methylarsenic species produced varied with the type of enrichment. Iron-reducing, manganese-reducing, sulfate-reducing and broad-spectrum anaerobic heterotrophic mixed cultures all produced methylarsenicals. Sulfate-reducing cultures produced higher concentrations of methylarsenicals (especially trimethyl species) than iron-or manganese-reducers. There is evidence that several of the methylarsenicals, which were hydride-reactive at pH 6, were methylarsenic(III) thiols. The organoarsenicals produced by enrichment cultures were the same as those detected in the porewater of the lake sediments used to initiate the enrichment cultures. Overall, this study demonstrates that microbes from anaerobic lake sediments can methylate (and demethylate) arsenic, a capability shared by manganese-, iron-, and sulfate-reducing microbial consortia.},
	keywords = {ANAEROBE, arsenic, MERCURY METHYLATION, MICROBIAL, ORGANOARSENICALS, SEDIMENT, THIOLS},
	isbn = {0268-2605},
	url = {<Go to ISI>://A1994PD64300014},
	author = {Bright, D. A. and Brock, S. and Cullen, W. R. and Hewitt, G. M. and Jafaar, J. and Reimer, K. J.}
}
