@article {4102,
	title = {Liquid chromatography and mass spectrometry for the speciation of arsenic animal feed additives},
	journal = {Journal of Chromatography A},
	volume = {764},
	number = {2},
	year = {1997},
	note = {ISI Document Delivery No.: WZ035Times Cited: 12Cited Reference Count: 29},
	month = {Mar},
	pages = {211-222},
	type = {Article},
	abstract = {A number of analytical techniques have been investigated for the determination of arsenic animal feed additive compounds. More specifically, liquid chromatography methods have been developed for the separation of these arsenicals. Micro liquid chromatography, which is a relatively new technique, shows a number of advantages for these analyses, especially when interfaced to mass spectrometers. Improved limits of detection, low solvent consumption, reduced amounts of stationary phase, as well as flow-rates easily accommodated by continuous-flow liquid secondary ion mass spectrometry and direct liquid introduction mass spectrometry, are some of the advantages we have observed when fabricating and using these columns. The off-line combination of micro liquid chromatography and electrothermal atomic absorption spectrometry improves the limit of detection for arsenic and shows potential for on-line coupling. Further use of the methods developed here may allow for a more detailed understanding of the fate and interactions of arylarsenicals in biological and environmental systems.},
	keywords = {3-NITRO-4-HYDROXYPHENYLARSONIC ACID, ARSENIC COMPOUNDS, ATOMIC-ABSORPTION SPECTROMETRY, BOMBARDMENT, detection, GROWTH PROMOTER, LC, PIGS, SEPARATION, ULTRAVIOLET DETECTION},
	isbn = {0021-9673},
	url = {<Go to ISI>://A1997WZ03500005},
	author = {Pergantis, S. A. and Cullen, W. R. and Chow, D. T. and Eigendor, G. K.}
}
@article {3001,
	title = {EMPLOYING PERMEABILITY COEFFICIENTS TO UNDERSTAND THE BIOMOBILITY AND BIOACCUMULATION OF COMPOUNDS SENSITIVE TO THE ENVIRONMENT},
	journal = {Bulletin of Environmental Contamination and Toxicology},
	volume = {52},
	number = {2},
	year = {1994},
	note = {ISI Document Delivery No.: ML036Times Cited: 5Cited Reference Count: 14},
	month = {Feb},
	pages = {171-175},
	type = {Article},
	keywords = {ARSENIC COMPOUNDS, CANDIDA-HUMICOLA},
	isbn = {0007-4861},
	url = {<Go to ISI>://A1994ML03600001},
	author = {Cullen, W. R. and Herring, F. G. and Nelson, J. C.}
}
@article {3091,
	title = {SPECIATION OF ARSENIC COMPOUNDS IN SOME MARINE ORGANISMS},
	journal = {Environmental Science \& Technology},
	volume = {28},
	number = {9},
	year = {1994},
	note = {ISI Document Delivery No.: PE258Times Cited: 43Cited Reference Count: 49},
	month = {Sep},
	pages = {1598-1604},
	type = {Article},
	abstract = {Speciation of arsenic compounds in some marine algae, bivalves, and crustaceans was studied by using two techniques: (i) high-performance liquid chromatography with inductively coupled plasma mass spectrometry detection and (ii) hydride generation atomic absorption spectrometry following microwave-assisted digestion. Arsenosugars were identified as the major arsenic compounds present in marine algae, whereas arsenobetaine was the dominant arsenic species present in crab and shrimp. In contrast to most previous reports, which claimed arsenobetaine as the only major arsenic species present in marine bivalves, this study revealed the presence of arsenosugars in addition to arsenobetaine in the bivalves. The speciation of arsenic in sample extracts and {\textquoteright}{\textquoteright}defrost liquid{\textquoteright}{\textquoteright} from previously frozen marine animal samples revealed that up to 48\% of the total arsenic in the sample can be released in the defrost liquid. Arsenic species found in the defrost liquid were identical with those in the sample extracts. Changes in arsenic speciation were observed in the sample extracts that were stored for a long term. Arsenobetaine in sample extracts that were stored at 4 degrees C for 9 months was decomposed to trimethylarsine oxide and two other unidentified arsenic species.},
	keywords = {ARSENIC COMPOUNDS, arsenobetaine, ATOMIC-ABSORPTION SPECTROMETRY, BOMBARDMENT MASS-SPECTROMETRY, ECKLONIA-RADIATA, HOMARUS-AMERICANUS, IDENTIFICATION, KELP, ORGANOARSENIC COMPOUNDS, TRACE-ELEMENTS, TRIMETHYLARSINE OXIDE},
	isbn = {0013-936X},
	url = {<Go to ISI>://A1994PE25800015},
	author = {Le, S. X. C. and Cullen, W. R. and Reimer, K. J.}
}
@article {2769,
	title = {THE BIOTRANSFORMATION OF MONOMETHYLARSONATE AND DIMETHYLARSINATE INTO ARSENOBETAINE IN SEAWATER AND MUSSELS},
	journal = {Applied Organometallic Chemistry},
	volume = {7},
	number = {5},
	year = {1993},
	note = {ISI Document Delivery No.: LV681Times Cited: 19Cited Reference Count: 12},
	month = {Sep},
	pages = {319-327},
	type = {Article},
	abstract = {Water-soluble H-3-labeled arsenic compounds were phenol-extracted from mussels (Mytilus edulis) and seawater after exposure to [H-3]monomethylarsonate (MMAA) and [H-3]dimethylarsinate (DMAA). Varying amounts of [H-3] arsenobetaine were found in mussels and seawater, depending upon the experimental conditions. The results indicate that arsenobetaine is principally biosynthesized by microscopic organisms in the seawater and that it is bioaccumulated by mussels. Total arsenic concentrations in mussel flesh, byssal threads and shells were also determined, showing concentration increases in all three compartments.},
	keywords = {ARSENIC COMPOUNDS, arsenobetaine, DIMETHYLARSINATE, ENVIRONMENT, MONOMETHYLARSONATE, MUSSELS, SEAWATER},
	isbn = {0268-2605},
	url = {<Go to ISI>://A1993LV68100004},
	author = {Cullen, W. R. and Nelson, J. C.}
}
@article {2768,
	title = {THE EFFECT OF ARSENICALS ON ALKALOID PRODUCTION BY CELL-SUSPENSION CULTURES OF CATHARANTHUS-ROSEUS},
	journal = {Applied Organometallic Chemistry},
	volume = {7},
	number = {7},
	year = {1993},
	note = {ISI Document Delivery No.: MQ500Times Cited: 1Cited Reference Count: 24},
	month = {Nov},
	pages = {477-486},
	type = {Article},
	abstract = {The effect of arsenic compounds on indole alkaloid production by cell suspension cultures of Catharanthus roseus was investigated. The analysis of indole alkaloids was achieved by using thermospray liquid chromatography-mass spectrometry (LC MS) which facilitated the rapid screening of alkaloid composition in cultures treated with different arsenicals at different times in their growth cycle. Treatment with dimethylarsinate (DMA), a non-selective herbicide, has a drastic inhibitory effect on alkaloid production although it is the least toxic arsenical to growth. Tryptamine, an early precursor in the biosynthesis of indole alkaloids, accumulates in cells treated with DMA, indicating that the initial step of condensation of tryptamine with secologanin is inhibited. Treatment with DMA during the early stationary phase of culture growth enhances the accumulation of some alkaloids, although some, such as catharanthine, are suppressed. The arsenicals arsenate and methylarsonate (MMA) have an inhibitory effect on alkaloid production when applied during the early growth stages. In contrast to MMA and DMA, arsenate has a stimulatory effect on catharanthine production when introduced to the culture during its early stationary phase. Thus the changes in the pattern of alkaloid accumulation on addition of arsenicals are dependent on the arsenic species and its concentration, as well as the time of application. This variable response indicates that each arsenical has a distinct mode of action on the secondary metabolic pathways of C. roseus.},
	keywords = {ALKALOID PRODUCTION, ARSENIC COMPOUNDS, CELLS, THERMOSPRAY LC MS},
	isbn = {0268-2605},
	url = {<Go to ISI>://A1993MQ50000005},
	author = {Cullen, W. R. and Hettipathirana, D. I.}
}
