@article {2231,
	title = {State-of-the-art in atmospheric pressure photoionization for LC/MS},
	journal = {Analytica Chimica Acta},
	volume = {627},
	number = {1},
	year = {2008},
	note = {ISI Document Delivery No.: 358IYTimes Cited: 23Cited Reference Count: 147Robb, Damon B. Blades, Michael W.Sp. Iss. SI},
	month = {Oct},
	pages = {34-49},
	type = {Review},
	abstract = {This review presents our perspective on the state-of-the-art of atmospheric pressure photoionization (APPI) for LC/MS. Its focus is on APPI{\textquoteright}s capabilities and how to utilize them fully. The introduction includes a brief recounting of the history of APPI{\textquoteright}s development, as well as a summary of its operating principles and current position in the field. The primary ionization mechanisms in APPI are then addressed, including direct analyte photoionization (PI), dopant/solvent PI, and thermospray. Next a summary of the ion-molecule reaction pathways available for analyte ionization is presented, along with the conditions required for activating them. APPI{\textquoteright}s performance characteristics are then examined. in effect, this review is an interim report on progress made since Rafaelli and Saba concluded that "The ability... to direct the preferential ion formation towards one particular type...can be extremely useful for qualitative and quantitative determinations. For this purpose, a better insight in the processes involved in the ionization step is strongly needed" [A. Raffaelli, A. Saba, Mass Spectrom. Rev. 22 (2003) 318]. In the conclusion, we focus on areas of APPI technology identified as being either unoptimized or largely unexplored, and having the potential to be improved upon-the crux being that with further research and development improvements in the performance, capabilities, and ease-of-use of APPI may reasonably be anticipated. (C) 2008 Elsevier B.V. All rights reserved.},
	keywords = {ACTIVATED CHEMICAL-IONIZATION, AROMATIC-HYDROCARBONS, atmospheric pressure, BROMINATED FLAME RETARDANTS, CARBON, ELECTROSPRAY-IONIZATION, HUMAN PLASMA, LC-MS/MS, liquid chromatography/mass, LIQUID-CHROMATOGRAPHY, PHOTOIONIZATION, POLYCYCLIC, POROUS GRAPHITIC, PROTON-TRANSFER, review, SPECTROMETRY, TANDEM-MASS-SPECTROMETRY},
	isbn = {0003-2670},
	url = {<Go to ISI>://000259911600004},
	author = {Robb, D. B. and Blades, M. W.}
}
@article {2276,
	title = {Utility of formaldehyde cross-linking and mass spectrometry in the study of protein-protein interactions},
	journal = {Journal of Mass Spectrometry},
	volume = {43},
	number = {6},
	year = {2008},
	note = {ISI Document Delivery No.: 319PPTimes Cited: 22Cited Reference Count: 54Sutherland, Brent W. Toews, Judy Kast, Juergen},
	month = {Jun},
	pages = {699-715},
	type = {Article},
	abstract = {For decades, formaldehyde has been routinely used to cross-link proteins in cells, tissue, and in some instances, even entire organisms. Due to its small size, formaldehyde can readily permeate cell walls and membranes, resulting in efficient cross-linking, i.e. the formation of covalent bonds between proteins, DNA, and other reactive molecules. Indeed, formaldehyde cross-linking is an instrumental component of many mainstream analytical/cell biology techniques including chromatin immunoprecipitation (ChIP) of protein-DNA complexes found in nuclei; immunohistological analysis of protein expression and localization within cells, tissues, and organs; and mass spectrometry (MS)-compatible silver-staining methodologies used to visualize low abundance proteins in polyacrylamide gels. However, despite its exquisite suitability for use in the analysis of protein environments within cells, formaldehyde has yet to be commonly employed in the directed analysis of protein-protein interactions and cellular networks. The general purpose of this article is to discuss recent advancements in the use of formaldehyde cross-linking in combination with MS-based methodologies. Key advantages and limitations to the use of formaldehyde over other cross-linkers and technologies currently used to study protein-protein interactions are highlighted, and formaldehyde-based experimental approaches that are proving very promising in their ability to accurately and efficiently identify novel protein-protein and multiprotein interaction complexes are presented. Copyright (c) 2008 John Wiley \& Sons, Ltd.},
	keywords = {ANTIGEN-RETRIEVAL, CHROMATIN IMMUNOPRECIPITATION, COMPLEXES, CROSS-LINKING, FORMALDEHYDE, IDENTIFICATION, IMMUNOHISTOCHEMISTRY, INTERACTION NETWORKS, MASS SPECTROMETRY, PARAFFIN-EMBEDDED TISSUE, protein interactions, PROTEOMICS, review, SURFACE-TOPOLOGY, THROUGHPUT},
	isbn = {1076-5174},
	url = {<Go to ISI>://000257176400001},
	author = {Sutherland, B. W. and Toews, J. and Kast, J.}
}
@article {397,
	title = {Applications of on-line weak affinity interactions in free solution capillary electrophoresis},
	journal = {Electrophoresis},
	volume = {23},
	number = {6},
	year = {2002},
	note = {ISI Document Delivery No.: 536KNTimes Cited: 26Cited Reference Count: 109},
	month = {Mar},
	pages = {815-822},
	type = {Review},
	abstract = {The impressive selectivity offered by capillary electrophoresis can in some cases be further increased when ligands or additives that engage in weak affinity interactions with one or more of the separated analytes are added to the electrophoresis buffer. This on-line affinity capillary electrophoresis approach is feasible when the migration of complexed molecules is different from the migration of free molecules and when separation conditions are nondenaturing. In this review, we focus on applying weak interactions as tools to enhance the separation of closely related molecules, e.g., drug enantiomers and on using capillary electrophoresis to characterize such interactions quantitatively. We describe the equations for binding isotherms, illustrate how selectivity can be manipulated by varying the additive concentrations, and show how the methods may be used to estimate binding constants. On-line affinity capillary electrophoresis methods are especially valuable for enantiomeric separations and for functional characterization of the contents of biological samples that are only available in minute quantities.},
	keywords = {affinity capillary electrophoresis, ALPHA(1)-ACID, AMYLOID-P COMPONENT, biomolecular interactions, capillary electrophoresis, CHIRAL SEPARATION, CHROMATOGRAPHY, CONSTANTS, ELECTROKINETIC, enantiomer separation, ENANTIOSELECTIVE PROTEIN, FRONTAL ANALYSIS, GLYCOPROTEIN, isotherms, MEASURE BINDING, PARTIAL-FILLING TECHNIQUE, PROTEIN-BINDING, review, separation methods, ZONE-ELECTROPHORESIS},
	isbn = {0173-0835},
	url = {<Go to ISI>://000174699400002},
	author = {Heegaard, N. H. H. and Nissen, M. H. and Chen, D. D. Y.}
}
@article {ISI:A1996VT05300002,
	title = {Structural and Functional Aspects of Metal Sites in Biology},
	journal = {Chem. Rev.},
	volume = {96},
	number = {7},
	year = {1996},
	month = {jan},
	pages = {2239{\textendash}2314},
	keywords = {PhD, review},
	issn = {0009-2665},
	doi = {10.1021/cr9500390},
	url = {http://pubs.acs.org/doi/abs/10.1021/cr9500390},
	author = {Holm, Richard H and Kennepohl, Pierre and Solomon, Edward I}
}
@article {3691,
	title = {The use of high-performance liquid chromatography for the speciation of organotin compounds},
	journal = {Applied Organometallic Chemistry},
	volume = {10},
	number = {5},
	year = {1996},
	note = {ISI Document Delivery No.: UW081Times Cited: 24Cited Reference Count: 89},
	month = {Jun},
	pages = {339-362},
	type = {Review},
	abstract = {This review of the use of high-performance liquid chromatography (HPLC) for the speciation of organotin compounds which are primarily of significance in the marine environment, is divided into sections on the basis of the different HPLC modes of separation. However, it should be noted that such a classification does not exist in reality. For instance, in an ion-pair reversed-phase system the separation mechanism for the ionic solutes may be ion-pair partitioning, or ion exchange, or both. The relevant practical information (e.g. column type, mobile phase, method of detection and detection limit) is presented in tabular form. MET A brief overview of the reported detection MIP methods is included, because the delay in development of an easily interfaced, specific and sensitive detector has hindered the use of HPLC for organotin speciation studies. The literature reviewed covers publications from 1977, the year of the first application of HPLC to organotin speciation, to April 1995.},
	keywords = {antifouling paints, ATOMIC-ABSORPTION SPECTROMETRY, BUTYLTIN COMPOUNDS, DIALKYLTIN HOMOLOGS, ELEMENTAL SPECIATION, environmental pollution, ENVIRONMENTAL-SAMPLES, FLUID CHROMATOGRAPHY, high-performance liquid chromatography, HPLC, marine environment, ORGANOMETALLIC COMPOUNDS, organotin, PHOTOMETRIC DETECTION, PLASMA-MASS-SPECTROMETRY, review, SIZE-EXCLUSION CHROMATOGRAPHY, SPECIATION, SUPERCRITICAL, tributyltin},
	isbn = {0268-2605},
	url = {<Go to ISI>://A1996UW08100002},
	author = {Harrington, C. F. and Eigendorf, G. K. and Cullen, W. R.}
}
