@article {2575,
	title = {An electropneumatic-heated nebulizer for enhancing spray ionization in PhotoSpray atmospheric pressure photoionization sources for liquid chromatography/mass spectrometry},
	journal = {Rapid Communications in Mass Spectrometry},
	volume = {23},
	number = {21},
	year = {2009},
	note = {ISI Document Delivery No.: 514YATimes Cited: 1Cited Reference Count: 30Robb, Damon B. Blades, Michael W.},
	month = {Nov},
	pages = {3394-3400},
	type = {Article},
	abstract = {We introduce a novel electropneumatic-heated nebulizer (EPn-HN), incorporating an electrified internal pneumatic nebulizer, to enhance the yield of sprayed ions from PhotoSpray (TM) atmospheric pressure photoionization (APPI) sources for liquid chromatography/mass spectrometry (LC/MS). Spray ionization from the pneumatic-heated nebulizers used in APPI sources provides a supplemental, complementary ionization method to be used for involatile and thermally labile compounds, otherwise intractable to APPI. Details of the construction and operation of the EPn-HN device are provided. The performance of the EPn-HN is demonstrated using two model compounds: substance P, a peptide used as a standard in studies of ion fragmentation mechanisms, and aztreonam, a thermally labile antibiotic. At the optimum voltage for spray ionization, improvements in sensitivity of two orders of magnitude are obtained relative to when the sprayer is grounded, the conventional case. Since both substance P and aztreonam cannot be detected using the APPI method alone, the results demonstrate how spray ionization from the EPn-HN may be used to extend the range of compounds amenable to PhotoSpray sources. Copyright (C) 2009 John Wiley \& Sons, Ltd.},
	keywords = {CHEMICAL-IONIZATION, ELECTROSPRAY, PEPTIDES, RESIDUES, TANDEM MASS-SPECTROMETRY},
	isbn = {0951-4198},
	url = {<Go to ISI>://000271431500006},
	author = {Robb, D. B. and Blades, M. W.}
}
@article {3936,
	title = {An extended mass range quadrupole for electrospray mass spectrometry},
	journal = {International Journal of Mass Spectrometry and Ion Processes},
	volume = {162},
	number = {1-3},
	year = {1997},
	note = {ISI Document Delivery No.: XD007Times Cited: 10Cited Reference Count: 39},
	month = {Mar},
	pages = {121-127},
	type = {Article},
	abstract = {The mass range of a quadrupole mass spectrometer with an electrospray source has been increased from m/z 4000 to m/z 8585 by lowering the radio frequency of the quadrupole power supply from 1.00 MHz to 683 kHz. Unit mass resolution at m/z 5030 can be achieved. The sensitivity below m/z 3000 shows only small changes as expected from phase space arguments. Spectra of poly propylene glycol and soybean agglutinin with peaks in the range m/z 4000-7000 are described. (C) 1997 Elsevier Science B.V.},
	keywords = {CLUSTERS, COMPLEXES, CONFORMATIONAL-CHANGES, DISSOCIATION, ELECTROSPRAY, high mass, IONIZATION-POTENTIALS, IONS, non-covalent, NONCOVALENT INTERACTIONS, PROTEINS, quadrupole mass spectrometer, SOYBEAN AGGLUTININ},
	isbn = {0168-1176},
	url = {<Go to ISI>://A1997XD00700011},
	author = {Collings, B. A. and Douglas, D. J.}
}
