@article {4305,
	title = {Optimization and immunological characterization of a photochemically coupled lysergic acid diethylamide (LSD) immunogen},
	journal = {Bioconjugate Chemistry},
	volume = {9},
	number = {5},
	year = {1998},
	note = {ISI Document Delivery No.: 125MYTimes Cited: 2Cited Reference Count: 41},
	month = {Sep-Oct},
	pages = {596-603},
	type = {Article},
	abstract = {A photoreactive heterobifunctional linker was used to prepare an immunogen in which lysergic acid diethylamide was indirectly coupled to keyhole limpet hemocyanin at multiple sites on the drug. It was possible to attach approximately 35 drug molecules to each protein using approximately equal amounts of both species during the reaction. The presence of buffer components or water severely compromised reaction efficiency, as estimated from the molar substitution ratio. Factors such as excess linker, pH, irradiation of dry matrix in the absence of buffer, and the drug/protein ratio used during photolysis were shown to have pronounced effects on reaction efficiency. Structural insights regarding immunogen coupling were obtained by determining the specificities of antibodies which were raised against the immunogen. Cross-reactivity data indicated that haptenation of protein likely occurred at positions N1 and N6 of lysergic acid diethylamide, which is plausible given the electrophilicity of the photogenerated aryl nitrene.},
	keywords = {BINDING, CROSS-LINKING REAGENTS, EPITOPE, FUNCTIONALIZED PERFLUOROPHENYL AZIDES, IMMUNOASSAY, IONIZATION MASS-SPECTROMETRY, photolysis, PROTEIN, RADIOIMMUNOASSAY, SERUM-ALBUMIN},
	isbn = {1043-1802},
	url = {<Go to ISI>://000076242400008},
	author = {Kerrigan, S. and Brooks, D. E.}
}
@article {7100,
	title = {PHOTOCHEMISTRY OF MACROCYCLIC KETONES WITHIN ZEOLITES - COMPETITION BETWEEN NORRISH TYPE-I AND TYPE-II REACTIVITY},
	journal = {Tetrahedron Letters},
	volume = {32},
	number = {52},
	year = {1991},
	note = {ISI Document Delivery No.: GX962Times Cited: 9Cited Reference Count: 32},
	month = {Dec},
	pages = {7675-7678},
	type = {Article},
	abstract = {Photolysis of macrocyclic mono- and diketones (1 and 2) included in X and Y zeolites gives Norrish type I products in addition to the products obtained via the Norrish type II process, the only observed process in isotropic media. Enhancement of the type I over the type II process is cation-dependent and especially large enhancements are obtained with Li and Na as cations. The zeolite effect is attributed to a reduction in the rate of the Norrish type II gamma-hydrogen abstraction process.},
	keywords = {ALKANONES, ALKYL, ALPHA-CLEAVAGE, DIBENZYL KETONES, FAUJASITES, KETONES, photolysis, TEMPERATURE-DEPENDENCE},
	isbn = {0040-4039},
	url = {<Go to ISI>://A1991GX96200012},
	author = {Ramamurthy, V. and Lei, X. G. and Turro, N. J. and Lewis, T. J. and Scheffer, J. R.}
}
