@inbook {1679, title = {New Tools for Life Science Research Based on Fiber-Optic-Linked Raman and Resonance Raman Spectroscopy}, booktitle = {New Approaches in Biomedical Spectroscopy}, series = {Acs Symposium Series}, volume = {963}, year = {2007}, note = {ISI Document Delivery No.: BKS87Times Cited: 2Cited Reference Count: 17Blades, M. W. Schulze, H. G. Konorov, S. O. Addison, C. J. Jirasek, A. I. Turner, R. F. B.Proceedings PaperSymposium on Approaches in Biomedical Spectroscopy2005Honolulu, HIAmer Chem Soc1155 SIXTEENTH ST NW, WASHINGTON, DC 20036 USA}, pages = {1-13}, publisher = {Amer Chemical Soc}, organization = {Amer Chemical Soc}, address = {Washington}, abstract = {Fiber-optic probes can exploit a favorable excitation radiation distribution within the sample that allows the use of higher laser power levels which, in turn, can yield a higher signal-to-noise ratio (SNR) for a given experiment without increasing the risk of analyte photo-damage. We have developed specialized fiber-optic probes for ultraviolet resonance Raman spectroscopy (UVRRS) that offer several advantages over conventional excitation/collection methods used for UVRRS. These probes are ideally suited for UVRRS studies involving biopolymers and small bio-molecules, in both native (e.g. physiological) and non-native (e.g. anoxic) solution environments. We have also developed novel probes based on hollow-core photonic band-gap fibers that virtually eliminate the generation of silica Raman scattering within the excitation fiber which often limits the utility of fiber-optic Raman probes in turbid media or near surfaces. These probes may offer advantages for some biomedical applications.}, keywords = {1, 2-DIOXYGENASE, PHOTONIC-CRYSTAL FIBER, PICOSECOND PULSES}, isbn = {0097-6156978-0-8412-7437-2}, url = {://000269122900001}, author = {Blades, M. W. and Schulze, H. G. and Konorov, S. O. and Addison, C. J. and Jirasek, A. I. and Turner, R. F. B.}, editor = {Kneipp, K. and Aroca, R. and Kneipp, H. and Wen trupByrne, E.} } @inbook {1679, title = {New Tools for Life Science Research Based on Fiber-Optic-Linked Raman and Resonance Raman Spectroscopy}, booktitle = {New Approaches in Biomedical Spectroscopy}, series = {Acs Symposium Series}, volume = {963}, year = {2007}, note = {ISI Document Delivery No.: BKS87Times Cited: 2Cited Reference Count: 17Blades, M. W. Schulze, H. G. Konorov, S. O. Addison, C. J. Jirasek, A. I. Turner, R. F. B.Proceedings PaperSymposium on Approaches in Biomedical Spectroscopy2005Honolulu, HIAmer Chem Soc1155 SIXTEENTH ST NW, WASHINGTON, DC 20036 USA}, pages = {1-13}, publisher = {Amer Chemical Soc}, organization = {Amer Chemical Soc}, address = {Washington}, abstract = {Fiber-optic probes can exploit a favorable excitation radiation distribution within the sample that allows the use of higher laser power levels which, in turn, can yield a higher signal-to-noise ratio (SNR) for a given experiment without increasing the risk of analyte photo-damage. We have developed specialized fiber-optic probes for ultraviolet resonance Raman spectroscopy (UVRRS) that offer several advantages over conventional excitation/collection methods used for UVRRS. These probes are ideally suited for UVRRS studies involving biopolymers and small bio-molecules, in both native (e.g. physiological) and non-native (e.g. anoxic) solution environments. We have also developed novel probes based on hollow-core photonic band-gap fibers that virtually eliminate the generation of silica Raman scattering within the excitation fiber which often limits the utility of fiber-optic Raman probes in turbid media or near surfaces. These probes may offer advantages for some biomedical applications.}, keywords = {1, 2-DIOXYGENASE, PHOTONIC-CRYSTAL FIBER, PICOSECOND PULSES}, isbn = {0097-6156978-0-8412-7437-2}, url = {://000269122900001}, author = {Blades, M. W. and Schulze, H. G. and Konorov, S. O. and Addison, C. J. and Jirasek, A. I. and Turner, R. F. B.}, editor = {Kneipp, K. and Aroca, R. and Kneipp, H. and Wen trupByrne, E.} } @article {1442, title = {Hollow-core photonic crystal fiber-optic probes for Raman spectroscopy}, journal = {Optics Letters}, volume = {31}, number = {12}, year = {2006}, note = {ISI Document Delivery No.: 051JGTimes Cited: 20Cited Reference Count: 21}, month = {Jun}, pages = {1911-1913}, type = {Article}, abstract = {We have implemented a new Raman fiber-optic probe design based on a hollow-core photonic-crystal excitation fiber surrounded by silica-core collection fibers. The photonic-crystal fiber offers low attenuation at the pump radiation wavelength, mechanical flexibility, high radiation stability, and low background noise. Because the excitation beam is transmitted through air inside the hollow-core fiber, silica Raman scattering is much reduced, improving the quality of the spectra obtained using probes of this design. Preliminary results show that the new probe design decreases the Raman background from the silica by approximately an order of magnitude compared to solid-core silica Raman probes. (c) 2006 Optical Society of America}, keywords = {FIBERS, PICOSECOND PULSES}, isbn = {0146-9592}, url = {://000238156800045}, author = {Konorov, S. O. and Addison, C. J. and Schulze, H. G. and Turner, R. F. B. and Blades, M. W.} } @article {1442, title = {Hollow-core photonic crystal fiber-optic probes for Raman spectroscopy}, journal = {Optics Letters}, volume = {31}, number = {12}, year = {2006}, note = {ISI Document Delivery No.: 051JGTimes Cited: 20Cited Reference Count: 21}, month = {Jun}, pages = {1911-1913}, type = {Article}, abstract = {We have implemented a new Raman fiber-optic probe design based on a hollow-core photonic-crystal excitation fiber surrounded by silica-core collection fibers. The photonic-crystal fiber offers low attenuation at the pump radiation wavelength, mechanical flexibility, high radiation stability, and low background noise. Because the excitation beam is transmitted through air inside the hollow-core fiber, silica Raman scattering is much reduced, improving the quality of the spectra obtained using probes of this design. Preliminary results show that the new probe design decreases the Raman background from the silica by approximately an order of magnitude compared to solid-core silica Raman probes. (c) 2006 Optical Society of America}, keywords = {FIBERS, PICOSECOND PULSES}, isbn = {0146-9592}, url = {://000238156800045}, author = {Konorov, S. O. and Addison, C. J. and Schulze, H. G. and Turner, R. F. B. and Blades, M. W.} }