@article {1675,
	title = {Enhanced reactivity results in reduced catalytic performance: Unexpected ligand reactivity of a bis(N-2,6-diisopropylphenylperflourophenyl-amidate)titanium-bis(diethyla mido) hydroamination precatalyst},
	journal = {Organometallics},
	volume = {26},
	number = {25},
	year = {2007},
	note = {Bexrud, Jason A. Li, Chunyu Schafer, Laurel L.},
	month = {Dec},
	pages = {6366-6372},
	abstract = {A bis(amidate)titanium-bis(amido) complex incorporating electron withdrawing pentafluorophenyl substituents has been prepared to enhance reactivity in this class of hydroamination precatalyst. This bis(N-2,6-diisopropylphenylperflourophenylamidate)titanium-bis(diethylam ido) titanium complex has been fully characterized, including its X-ray crystal structure. As a precatalyst, the title compound proved to be effective for intermolecular hydroamination of internal and terminal alkynes with primary amines with yields as high as 97\% and modest intramolecular alkene hydroamination. However, the elevated reactivity of this complex also resulted in reduced Markovnikov/anti-Markovnikov selectivity with some terminal alkynes. Substrate scope limitations revealed that this complex is susceptible to decomposition as a direct consequence of nucleophilic addition of the amine substrate to the pentafluorophenyl substituent of the amidate ligand.},
	isbn = {0276-7333},
	url = {<Go to ISI>://000251199900037},
	author = {Bexrud, J. A. and Li, C. Y. and Schafer, L. L.}
}
