@article {4638, title = {Porphyrins incorporating heterocyclic N-oxides: (oxidopyridyl)porphyrins, porphyrin-N-oxides, and a tirapazamine-porphyrin conjugate}, journal = {Canadian Journal of Chemistry-Revue Canadienne De Chimie}, volume = {77}, number = {2}, year = {1999}, note = {ISI Document Delivery No.: 188AZTimes Cited: 9Cited Reference Count: 41}, month = {Feb}, pages = {182-198}, type = {Article}, abstract = {{Porphyrins containing one to four 3-pyridyl groups as meso-substituents were synthesized via a mixed aldehyde condensation, and then "N-oxidized" with m-chloroperbenzoic acid to produce five novel (oxidopyridyl) porphyrins and seven porphyrin-N-oxides which were characterized by analysis and spectroscopic methods, especially NMR; an X-ray crystal structure of 5-(1-oxido-4-pyridyl)-10, 15,20-triphenylporphyrin was also obtained. Crystals of (oxidopyridyl)triphenylporphyrin are tetragonal}, keywords = {(oxidopyridyl)porphyrins, ANTICANCER, BIOREDUCTIVE DRUGS, DESIGN, DRUGS, FUNCTIONAL-GROUPS, NICKEL(II), PHENYL, PHOTODYNAMIC THERAPY, porphyrin-N-oxides, tirapazamine}, isbn = {0008-4042}, url = {://000079823200003}, author = {Posakony, J. J. and Pratt, R. C. and Rettig, S. J. and James, Brian R. and Skov, K. A.} }