@article {4964,
	title = {Novel natural products from soil DNA libraries in a streptomycete host},
	journal = {Organic Letters},
	volume = {2},
	number = {16},
	year = {2000},
	note = {ISI Document Delivery No.: 341TGTimes Cited: 82Cited Reference Count: 7},
	month = {Aug},
	pages = {2401-2404},
	type = {Article},
	abstract = {[GRAPHICS] As a route to accessing the potential chemical diversity of uncultivable microbes from the soil, combinatorial biosynthetic libraries were constructed by cloning large fragments of DNA isolated from soil into a Streptomyces lividans host. Four novel compounds, terragines A (1), B (2), C (3), and D (4), were isolated from recombinant 436-s4-5b1, and another novel compound, terragine E (5), was isolated from 446-s3-102g1. The structures were determined by a combination of spectroscopic techniques, primarily 2D NMR.},
	isbn = {1523-7060},
	url = {<Go to ISI>://000088605200003},
	author = {Wang, G. Y. S. and Graziani, E. and Waters, B. and Pan, W. B. and Li, X. and McDermott, J. and Meurer, G. and Saxena, G. and Andersen, R. J. and Davies, J.}
}
