@article {1407,
	title = {Sulfated meroterpenoids from the Brazilian sponge Callyspongia sp. are inhibitors of the antileishmaniasis target adenosine phosphoribosyl transferase},
	journal = {Journal of Organic Chemistry},
	volume = {71},
	number = {23},
	year = {2006},
	note = {ISI Document Delivery No.: 101QKTimes Cited: 14Cited Reference Count: 23Gray, Christopher A. de Lira, Simone P. Silva, Marcio Pimenta, Eli F. Thiemann, Otavio H. Oliva, Glaucius Hajdu, Eduardo Andersen, Raymond J. Berlinck, Roberto G. S.},
	month = {Nov},
	pages = {8685-8690},
	type = {Article},
	abstract = {Three new disulfated meroterpenoids, ilhabelanol (1), ilhabrene (2), and isoakaterpin (3), have been isolated from extracts of the Brazilian marine sponge Callyspongia sp. Isoakaterpin (3) inhibits Leishmania spp. adenosine phosphoribosyl transferase with an IC50 of 1.05 mu M. The structures of 1, 2, and 3 were elucidated by analysis of one- and two-dimensional NMR data. Ilhabelanol (1) and ilhabrene (2) both have unprecedented meroterpenoid carbon skeletons.},
	keywords = {AKA ADOCIA SP, AKATERPIN, chemotherapy, DRUGS, HEXAPRENOID HYDROQUINONES, LEISHMANIASIS, NATURAL-PRODUCTS, TOXICLONA-TOXIUS},
	isbn = {0022-3263},
	url = {<Go to ISI>://000241755300001},
	author = {Gray, C. A. and de Lira, S. P. and Silva, M. and Pimenta, E. F. and Thiemann, O. H. and Oliva, G. and Hajdu, E. and Andersen, R. J. and Berlinck, R. G. S.}
}
