@article {9841,
	title = {Bafilomycins Produced in Culture by Streptomyces spp. Isolated from Marine Habitats Are Potent Inhibitors of Autophagy.},
	journal = {Journal of Natural Products},
	volume = {73},
	year = {2010},
	note = {CAPLUS AN 2010:22388(Journal)},
	month = {2010///},
	pages = {422 - 427},
	publisher = {American Chemical Society-American Society of Pharmacognosy},
	abstract = {Five new bafilomycins, F (1) to J (5), have been isolated from lab. cultures of two Streptomyces spp. obtained from marine sediments collected in British Columbia, and their structures have been elucidated by detailed anal. of spectroscopic data and the synthesis of model compds. The new bafilomycins F (1), G (2), H (3), and J (5) along with several co-occurring known analogs showed potent inhibition of autophagy in microscopy and biochem. assays. The thiomorpholinone fragment present in bafilomycin F (1) has not previously been found in a natural product. [on SciFinder(R)]},
	keywords = {Streptomyces bafilomycin isolation autophagy inhibitor},
	isbn = {0163-3864},
	author = {Carr,Gavin and Williams,David E. and Diaz-Marrero,Ana R. and Patrick,Brian O. and Bottriell,Helen and Balgi,Aruna D. and Donohue,Elizabeth and Roberge,Michel and Andersen, R. J.}
}
